Peiffer-Smadja, Nathan Poda, Armel Ouedraogo, Abdoul-Salam Guiard-Schmid, Jean-Baptiste Delory, Tristan Le Bel, Josselin Bouvet, Elisabeth Lariven, Sylvie Jeanmougin, Pauline Ahmad, Raheelah
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Published in
Journal of Medical Internet Research
Background Suboptimal use of antibiotics is a driver of antimicrobial resistance (AMR). Clinical decision support systems (CDSS) can assist prescribers with rapid access to up-to-date information. In low- and middle-income countries (LMIC), the introduction of CDSS for antibiotic prescribing could have a measurable impact. However, interventions to...
Ngo, Tony Stephens, Bryan S Gustavsson, Martin Holden, Lauren G Abagyan, Ruben Handel, Tracy M Kufareva, Irina
Chemokines and their receptors are orchestrators of cell migration in humans. Because dysregulation of the receptor-chemokine system leads to inflammation and cancer, both chemokines and receptors are highly sought therapeutic targets. Yet one of the barriers for their therapeutic targeting is the limited understanding of the structural principles ...
Amman, Brian R Bird, Brian H Bakarr, Ibrahim A Bangura, James Schuh, Amy J Johnny, Jonathan Sealy, Tara K Conteh, Immah Koroma, Alusine H Foday, Ibrahim
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Marburg virus (MARV) causes sporadic outbreaks of severe Marburg virus disease (MVD). Most MVD outbreaks originated in East Africa and field studies in East Africa, South Africa, Zambia, and Gabon identified the Egyptian rousette bat (ERB; Rousettus aegyptiacus) as a natural reservoir. However, the largest recorded MVD outbreak with the highest cas...
Noda, Orion
Abstract The field of International Relations (IR) is barely ‘international’. Scholars have voiced their concerns and as a result, we have witnessed calls for diversity and inclusion in IR, be it in publication or in syllabi. Notwithstanding, the misrepresentation of non-Western scholars in the production of knowledge is significant. This article s...
Antúnez Moreno, Juan Carlos
The DAESH has been particularly successful in recruiting Western women. There are differences in their profile and motivation with their male counterparts.The DAESH offered an alternative to Western secularist feminism, substituting salvation for emancipation (empowerment without genderequality). DAESH ́s Western women played different roles. They ...
Dastugue, Gérard
Western. West. The western is the American cinematic genre, the only one to exist in itself,defined by its geographical location (west of the United States) to turn the land in a real character.In history, since the pilgrim fathers, this wild and far west may have been condemned to beconquered by this « Manifest Destiny », this American Profress wh...
Tomasovic, Dick
Miyoshi, So Krishnaswami, Sriram Toyoizumi, Shigeyuki Nakamura, Hiroyuki Zwillich, Samuel H.
Published in
Clinical Pharmacology in Drug Development
The aim of the study was to characterize the pharmacokinetics, safety, and tolerability of tofacitinib, an oral Janus kinase inhibitor for the treatment of rheumatoid arthritis, psoriatic arthritis, and ulcerative colitis in healthy Japanese volunteers, and to compare these outcomes with those of healthy Western volunteers. Twenty‐five volunteers (...
Clancy, Kathryn B.H. Davis, Jenny L.
WEIRD populations, or those categorized as Western, educated, industrialized, rich, and democratic, are sampled in the majority of quantitative human subjects research. Although this oversampling is criticized in some corners of social science research, it is not always clear what we are critiquing. In this article, we make three interventions into...
Kent, AJ Mayer, N Inman, JL Hochman-Mendez, C Bissell, MJ Robertson, C
Laminin-111 (Ln-1), an extracellular matrix (ECM) glycoprotein found in the basement membrane of mammary gland epithelia, is essential for lactation. In mammary epithelial cells (MECs), dystroglycan (Dg) is believed to be necessary for polymerization of laminin-111 into networks., thus we asked whether correct polymerization could compensate for Dg...