Garfein, Richard Golub, Elizabeth T Greenberg, Alan E Hagan, Holly Hanson, Debra L Hudson, Sharon M Kapadia, Farzana Latka, Mary H Ouellet, Lawrence J Purcell, David W
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Objectives: To evaluate whether a behavioral intervention, which taught peer education skills, could reduce injection and sexual risk behaviors associated with primary HIV and hepatitis C virus infection (HCV) among young injection drug users (IDU). Design: We conducted a randomized controlled trial involving HIV and HCV antibodynegative IDU, aged ...
DeGutis, Joseph M. Van Vleet, Thomas M.
Published in
Frontiers in Human Neuroscience
Hemispatial neglect is a debilitating disorder marked by a constellation of spatial and non-spatial attention deficits. Patients’ alertness deficits have shown to interact with lateralized attention processes and correspondingly, improving tonic/general alertness as well as phasic/moment-to-moment alertness has shown to ameliorate spatial bias. How...
Wenzek, Christina Steinbach, Philine Wirsdörfer, Florian Sutter, Kathrin Boehme, Julia D Geffers, Robert Klopfleisch, Robert Bruder, Dunja Jendrossek, Verena Buer, Jan
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Published in
iScience
CD47 is an ubiquitously expressed surface molecule with significant impact on immune responses. However, its role for antiviral immunity is not fully understood. Here, we revealed that the expression of CD47 on immune cells seemed to disturb the antiviral immune response as CD47-deficient mice (CD47-/-) showed an augmented clearance of influenza A ...
Kim, Taewoo Min, Kyoung Il Yang, Jeong-Sun Kim, Jun Won Cho, Junhyung Kim, Yun Ho Lee, Jeong Seok Kim, Young Tae Kim, Kyung-Chang Kim, Jeong Yeon
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Published in
iScience
With the continuous emergence of highly transmissible SARS-CoV-2 variants, the comparison of their infectivity has become a critical issue for public health. However, a direct assessment of the viral characteristic has been challenging because of the lack of appropriate experimental models and efficient methods. Here, we integrated human alveolar o...
Gao, Shan-Shan Shi, Run Sun, Jing Tang, Yanhong Zheng, Zhenhua Li, Jing-Feng Li, Huan Zhang, Jie Leng, Qibin Xu, Jiang
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Published in
iScience
Identification of host factors facilitating pathogen entry is critical for preventing infectious diseases. Here, we report a tagging system consisting of a viral receptor-binding protein (RBP) linked to BioID2, which is expressed on the cell surface via a GPI anchor. Using VSV or Zika virus (ZIKV) RBP, the system (BioID2- RBP(V)-GPI; BioID2-RBP(Z)-...
De Clerck, Caroline Josselin, Laurie Vangoethem, Valentine Lassois, Ludivine Fauconnier, Marie-Laure Jijakli, Haissam
peer reviewed / Quorum sensing (QS) is often defined as a mechanism of microbial communication that can regulate microbial behaviors in accordance with population density. Much is known about QS mechanisms in bacteria, but fungal QS research is still in its infancy. In this study, the molecules constituting the volatolomes of the plant pathogenic f...
Delva, Jonas L. Daled, Simon Van Waesberghe, Cliff Almey, Ruben Jansens, Robert J. J. Deforce, Dieter Dhaenens, Maarten Favoreel, Herman W.
Published in
Journal of Virology
Pseudorabies virus (PRV) is a member of the alphaherpesvirus subfamily and the causative agent of Aujeszky’s disease in pigs. Driven by the large economic losses associated with PRV infection, several vaccines and vaccine programs have been developed. To this day, the attenuated Bartha strain, generated by serial passaging, represents the golden st...
Luque-Paz, David Tattevin, Pierre Loubet, Paul Bénézit, François Thibault, Vincent Lainé, Fabrice Vanhems, Philippe Amour, Selilah Lina, Bruno Duval, Xavier
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Published in
Scientific Reports
Inhaled corticosteroids (ICS) have been associated with increased risk of pneumonia. Their impact on respiratory virus infections is unclear. We performed a post-hoc analysis of the FLUVAC cohort, a multicenter prospective cohort study of adults hospitalized with influenza-like illness (ILI) during six consecutive influenza seasons (2012–2018). All...
Morris, Sheldon R Jain, Sonia Blumenthal, Jill Bolan, Robert Dubé, Michael P Henderson, Philip Corado, Katya Sun, Shelly He, Feng Chow, Karen
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BackgroundTransgender and nonbinary individuals at risk for HIV may benefit from adherence support for pre-exposure prophylaxis.MethodsBetween June 2017 and September 2020, 255 transgender and nonbinary individuals received daily oral tenofovir disoproxil fumarate/emtricitabine for 48 weeks randomized 1:1 to receive individualized Texting for Adher...
Lansiaux, Edouard Jain, Nityanand Laivacuma, Sniedze Reinis, Aigars
Published in
Virus research
First described in 1958, the human monkeypox virus (hMPXV) is a neglected zoonotic pathogen closely associated with the smallpox virus. The virus usually spreads via close contact with the infected animal or human and has been endemic mostly in parts of the African continent. However, with the recent increase in trade, tourism, and travel, the viru...