Huang, Rui Zhu, Li Xue, Leyang Yan, Xuebing Wang, Jian Huang, Songping Zhang, Biao Xu, Tianmin Ji, Fang Li, Chunyang
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Published in
Virology Journal
BackgroundThe clinical and virological course of patients with coronavirus disease 2019 (COVID-19) are lacking. We aimed to describe the clinical and virological characteristics of COVID-19 patients from 10 designated hospitals in 10 cities of Jiangsu province, China. The factors associated with the clearance of SARS-CoV-2 were investigated.Methods...
Randremanana, Rindra Vatosoa Andriamandimby, Soa-Fy Rakotondramanga, Jean Marius Razanajatovo, Norosoa Harline Mangahasimbola, Reziky Tiandraza Randriambolamanantsoa, Tsiry Hasina Ranaivoson, Hafaliana Christian Rabemananjara, Harinirina Aina Razanajatovo, Iony Razafindratsimandresy, Richter
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BackgroundFollowing the first detection of SARS-CoV-2 in passengers arriving from Europe on 19 March 2020, Madagascar took several mitigation measures to limit the spread of the virus in the country.MethodsNasopharyngeal and/or oropharyngeal swabs were collected from travellers to Madagascar, suspected SARS-CoV-2 cases and contact of confirmed case...
de Araújo, Leonardo José Tadeu Gonzalez, Lorenzo Lang Buss, Lewis Fletcher Guerra, Juliana Mariotti Gomez, David Salas Ferreira, Camila Santos da Silva Cirqueira, Cinthya Santos Ghillardi, Fábio Witkin, Steven S. Sabino, Ester Cerdeira
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Published in
Revista de Saúde Pública
OBJECTIVE To evaluate the performance of post mortem laboratory analysis in identifying the causes of hemorrhagic fever and/or neuroinvasive disease in deaths by arbovirus infection. METHODS Retrospective cross-sectional study based on the differential analysis and final outcome obtained in patients whose samples underwent laboratory testing for ar...
Kieft, Kristopher Zhou, Zhichao Anderson, Rika E Buchan, Alison Campbell, Barbara J Hallam, Steven J Hess, Matthias Sullivan, Matthew B Walsh, David A Roux, Simon
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Microbial sulfur metabolism contributes to biogeochemical cycling on global scales. Sulfur metabolizing microbes are infected by phages that can encode auxiliary metabolic genes (AMGs) to alter sulfur metabolism within host cells but remain poorly characterized. Here we identified 191 phages derived from twelve environments that encoded 227 AMGs fo...
Marotz, Clarisse Belda-Ferre, Pedro Ali, Farhana Das, Promi Huang, Shi Cantrell, Kalen Jiang, Lingjing Martino, Cameron Diner, Rachel E Rahman, Gibraan
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BackgroundSARS-CoV-2 is an RNA virus responsible for the coronavirus disease 2019 (COVID-19) pandemic. Viruses exist in complex microbial environments, and recent studies have revealed both synergistic and antagonistic effects of specific bacterial taxa on viral prevalence and infectivity. We set out to test whether specific bacterial communities p...
Kwon, Soo Bin Ernst, Jason
Given the global impact and severity of COVID-19, there is a pressing need for a better understanding of the SARS-CoV-2 genome and mutations. Multi-strain sequence alignments of coronaviruses (CoV) provide important information for interpreting the genome and its variation. We apply a comparative genomics method, ConsHMM, to the multi-strain alignm...
Telwatte, Sushama Kumar, Nitasha Vallejo-Gracia, Albert Kumar, G Renuka Lu, Chuanyi M Ott, Melanie Wong, Joseph K Yukl, Steven A
A hallmark of coronavirus transcription is the generation of negative-sense RNA intermediates that serve as the templates for the synthesis of positive-sense genomic RNA (gRNA) and an array of subgenomic mRNAs (sgRNAs) encompassing sequences arising from discontinuous transcription. Existing PCR-based diagnostic assays for SAR-CoV-2 are qualitative...
Weber, Stefanie Ramirez, Christina M Weiser, Barbara Burger, Harold Doerfler, Walter
Scientists and the public were alarmed at the first large viral variant of SARS-CoV-2 reported in December 2020. We have followed the time course of emerging viral mutants and variants during the SARS-CoV-2 pandemic in ten countries on four continents. We examined > 383,500 complete SARS-CoV-2 nucleotide sequences in GISAID (Global Initiative of Sh...
Cardobi, Nicolò Benetti, Giulio Cardano, Giuseppe Arena, Cinzia Micheletto, Claudio Cavedon, Carlo Montemezzi, Stefania
Published in
La Radiologia Medica
Purpose To classify COVID-19, COVID-19-like and non-COVID-19 interstitial pneumonia using lung CT radiomic features. Material and Methods CT data of 115 patients with respiratory symptoms suspected for COVID-19 disease were retrospectively analyzed. Based on the results of nasopharyngeal swab, patients were divided into two main groups, COVID-19 po...
Dellicour, Simon Hong, Samuel L Vrancken, Bram Chaillon, Antoine Gill, Mandev S Maurano, Matthew T Ramaswami, Sitharam Zappile, Paul Marier, Christian Harkins, Gordon W
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During the first phase of the COVID-19 epidemic, New York City rapidly became the epicenter of the pandemic in the United States. While molecular phylogenetic analyses have previously highlighted multiple introductions and a period of cryptic community transmission within New York City, little is known about the circulation of SARS-CoV-2 within and...
