Xian, Tew Hui Sinniah, Kurunathan Yean, Chan Yean Krishnamoorthy, Venkateskumar Bahari, Mohd Baidi Ravichandran, Manickam Prabhakaran, Guruswamy
Published in
BMC Immunology
BackgroundCholera, an acute watery diarrhoeal disease caused by Vibrio cholerae serogroup O1 and O139 across the continents. Replacing the existing WHO licensed killed multiple-dose oral cholera vaccines that demand ‘cold chain supply’ at 2–8 °C with a live, single-dose and cold chain-free vaccine would relieve the significant bottlenecks and cost ...
Dorman, Matthew Domman, Daryl Uddin, Muhammad Ikhtear Sharmin, Salma Afrad, Mokibul Hassan Begum, Yasmin Ara Qadri, Firdausi Thomson, Nicholas R
Anandan, Shalini Devanga Ragupathi, Naveen Kumar Muthuirulandi Sethuvel, Dhiviya Prabaa Thangamani, Suji Veeraraghavan, Balaji
Published in
Gut Pathogens
Vibrio cholerae is responsible for the cause of severe life-threatening infection known as cholera. The study aimed to analyze the genetic make-up of V. cholerae O139 isolates from India and compare its phylogeny with the global strains. The genome data revealed that all isolates were of same sequence type (ST69) which belongs to seventh pandemic c...
Labbate, Maurizio Orata, Fabini D Petty, Nicola K Jayatilleke, Nathasha D King, William L Kirchberger, Paul C Allen, Chris Mann, Gulay Mutreja, Ankur Thomson, Nicholas R
...
Labbate, M Orata, FD Petty, NK Jayatilleke, ND King, WL Kirchberger, PC Allen, C Mann, G Mutreja, A Thomson, NR
...
© 2016 The Author(s). Cholera is a devastating diarrhoeal disease caused by certain strains of serogroup O1/O139 Vibrio cholerae. Mobile genetic elements such as genomic islands (GIs) have been pivotal in the evolution of O1/O139 V. cholerae. Perhaps the most important GI involved in cholera disease is the V. cholerae pathogenicity island 1 (VPI-1)...
Li, Xiujun Wang, Duochun Li, Baisheng Zhou, Haijian Liang, Song Ke, Changwen Deng, Xiaoling Kan, Biao Morris, J Glenn Jr Cao, Wuchun
...
Published in
Canadian journal of microbiology
Toxigenic isolates of Vibrio cholerae serogroups O1 and O139 from aquatic reservoirs are a key source for recurrent epidemics of cholera in human populations. However, we do not have an optimal understanding of the microbiology of the strains within these reservoirs, particularly outside of the time periods when there are active cholera cases in th...
Islam, Md Saiful Shahik, Shah Md Sohel, Md Patwary, Noman I A Hasan, Md Anayet
Published in
Genomics & informatics
In developing countries threat of cholera is a significant health concern whenever water purification and sewage disposal systems are inadequate. Vibrio cholerae is one of the responsible bacteria involved in cholera disease. The complete genome sequence of V. cholerae deciphers the presence of various genes and hypothetical proteins whose function...
Fouts, Derrick E Klumpp, Jochen Bishop-Lilly, Kimberly A Rajavel, Mathumathi Willner, Kristin M Butani, Amy Henry, Matthew Biswas, Biswajit Li, Manrong Albert, M John
...
Published in
Virology Journal
BackgroundVibrio cholerae O139 Bengal is the only serogroup other than O1 implicated in cholera epidemics. We describe the isolation and characterization of an O139 serogroup-specific phage, vB_VchP_VchO139-I (ϕVchO139-I) that has similar host range and virion morphology as phage vB_VchP_JA1 (ϕJA1) described previously. We aimed at a complete molec...
Tu Nguyen, Dong Cuong Ngo, Tuan Hoang Tran, Huy Huong Le, Thanh Thu Nguyen, Hoai Minh Nguyen, Binh Duong Tran, Nhu Yamashiro, Tetsu Ehara, Masahiko
During the cholera survey in Namdinh province (northern Vietnam) in July, 2010, one strain of Vibrio cholerae O139 was isolated from 7 environmental water samples positive for ctxA, toxR, VCO139 genes and named as V. cholerae O139, ND1 strain. This strain was lysogenic harbouring a genome similar to the filamentous phage fs1. The replicative form D...
Valdespino, J.L. García-García, L.
Published in
Encyclopedia of Environmental Health, Five-Volume Set
Cholera is one of the main causes of morbidity and mortality in some countries in Asia and Africa and represents a key indicator of social development. Recent evidence showing how the flexibility of the genome of Vibrio cholerae allows its survival in the aquatic environment and in the human host is reviewed. Available evidence is suggestive that h...
