Park, Yong-Eun
Published in
World Journal of Surgical Oncology
Background The interplay between the nervous system and cancer plays an important role in the initiation and progression of gastric cancer. Few studies have presented evidence that the sympathetic nervous system inhibits the occurrence and development of gastric cancer while the parasympathetic nervous system promotes the growth of gastric cancer. ...
Li, Yan-Ting Yuan, Wen-Zhen Jin, Wei-Lin
Published in
Biochimica et biophysica acta. Reviews on cancer
The vagus nerve (VN) is the main parasympathetic nerve of the autonomic nervous system. It is widely distributed in the gastrointestinal tract and maintains gastrointestinal homeostasis with the sympathetic nerve under physiological conditions. The VN communicates with various components of the tumor microenvironment to positively and dynamically a...
Sheikhpour, Elnaz Mard, Seyed Ali Farbood, Yaghoub Bavarsad, Kowsar Sarkaki, Alireza
Published in
Life sciences
The neuropathology of Parkinson's disease (PD) is complex and affects multiple systems of the body beyond the central nervous system. This study examined the effects of gallic acid (GA) and gastrointestinal vagotomy (VG) on motor, cognitive, intestinal transit time, and thalamic nuclei electrical power in an animal model of PD induced by rotenone. ...
Kapralou, Athena N Chrousos, George P
Published in
Metabolism: clinical and experimental
Bariatric-metabolic surgery (BMS) in patients with obesity frequently leads to remission of concurrent type 2 diabetes mellitus (T2DM), even before body weight loss takes place. This is probably based on the correction of a dysmetabolic cycle in the gastrointestinal physiology of T2DM that includes increased vagus-dependent exocrine pancreatic secr...
Wierdak, Mateusz Korbut, Edyta Hubalewska-Mazgaj, Magdalena Surmiak, Marcin Magierowska, Katarzyna Wójcik-Grzybek, Dagmara Pędziwiatr, Michał Brzozowski, Tomasz Magierowski, Marcin
Published in
Obesity surgery
Obesity may be treated by bariatric procedures and is related to enterohormone release modulation. Nevertheless, a majority of commonly used surgical procedures have a significant impact on vagus nerve function by breaking the connections with its gastric branches. In the case of an intragastric balloon (BAL), this interaction is unclear. However, ...
Yan, Jing-Ting Liu, Xiao-Yu Liu, Jing-Hua Li, Guang-Wen Zheng, Li-Fei Zhang, Xiao-Li Zhang, Yue Feng, Xiao-Yan Zhu, Jin-Xia
Published in
Cell and tissue research
Patients with Parkinson's disease (PD) have a higher incidence rate of duodenal ulcers. The mucus barrier provides the first line of defense for duodenal mucosal protection. However, it is unknown whether duodenal mucus secretion is affected in PD. In the present study, we used the rats microinjected 6-hydroxydopamine (6-OHDA) into the bilateral su...
Li, Nana Liu, Lu Sun, Menghan Wang, Ruiliang Jin, Wenjie Liu, Cunming Hu, Youli
Published in
BMC Anesthesiology
BackgroundPostoperative nausea and vomiting (PONV) as a clinically most common postoperative complication requires multimodal antiemetic medications targeting at a wide range of neurotransmitter pathways. Lacking of neurobiological mechanism makes this ‘big little problem’ still unresolved. We aim to investigate whether gut-vagus-brain reflex gener...
Qian, Kai Liu, Jiaqi Cao, Yiqing Yang, Jing Qiu, Shuang
Published in
Molecular Brain
Insular cortex is a critical brain region that participates in the interoceptive sensations. Here, we combined the iDISCO + method and Fos immunostaining to confirm that the middle part of the right-side, but not the left-side, insular cortex in adult male mice is activated by intraperitoneal injection of lithium chloride. Lateralized activation of...
Tibensky, M Mravec, B
Published in
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico
The nervous system plays an important role in cancer initiation and progression. Accumulated evidences clearly show that the sympathetic nervous system exerts stimulatory effects on carcinogenesis and cancer growth. However, the role of the parasympathetic nervous system in cancer has been much less elucidated. Whereas retrospective studies in vago...
Yoshizawa, Tomohiko Funahashi, Makoto
Published in
Journal of oral biosciences
The aim of the present study is to demonstrate the effects of inhaled methyl methacrylate (MMA) on the excitability of neurons in the area postrema (AP). We also investigated the relation between vagal afferent inputs and responding cells in the AP. We set up two groups of experimental animals, such as rats inhaling MMA and rats inhaling room air. ...
