Gates, Allison Pillay, Jennifer Reynolds, Donna Stirling, Rob Traversy, Gregory Korownyk, Christina Moore, Ainsley Thériault, Guylène Thombs, Brett D. Little, Julian
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Published in
Systematic Reviews
PurposeTo inform recommendations by the Canadian Task Force on Preventive Health Care on screening in primary care for the prevention and early detection of cervical cancer by systematically reviewing evidence of (a) effectiveness; (b) test accuracy; (c) individuals’ values and preferences; and (d) strategies aimed at improving screening rates.Meth...
Song, F B Du, H Xiao, A M Wang, C Huang, X Yan, P S Liu, Z H Qu, X F Belinson, J E R O M E L Wu, R F
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Published in
Zhonghua fu chan ke za zhi
目的： 探讨p16INK4a免疫细胞化学染色（p16INK4a染色）作为新一代子宫颈细胞学检查技术在人群子宫颈癌初筛与辅助常规细胞学检查及高危型（HR）-HPV初筛后的二次筛查中的价值。 方法： 募集2016—2018年深圳及周边地区25~65岁有性生活的非妊娠期妇女5 747例，采用HR-HPV联合子宫颈液基细胞学检查（LCT）进行子宫颈癌初筛；并行p16INK4a染色，其中902例在初筛的同时进行p16INK4a染色，其余4 845例为HR-HPV与LCT初筛阳性回叫行阴道镜检查时取样进行p16INK4a染色。将具有完整LCT检查、HR-HPV检测、p16INK4a染色及子宫颈活检后病理诊断结果者纳入本研究。以组织学病理诊断为“金标准”，评价p16INK4a染色作为子宫颈癌初筛、辅助LC...
Wang, Zhiling Gu, Ying Wang, Hui Chen, Junyu Zheng, Yawen Cui, Baoxia Yang, Xingsheng
Published in
Virology Journal
BackgroundTo investigate distributions of cervical lesions and factors associated with the severity of the cervical lesions in high-risk HPV (hr-HPV) positive women with atypical squamous cells of undetermined significance (ASC-US) cytology.MethodsClinical information of 250,000 women who underwent HPV and cytological test was collected from Januar...
Choi, Yae Ji Hwang, Woo Yeon Lee, Nara Kim, Miseon Suh, Dong Hoon Kim, Kidong Kim, Yong Beom No, Jae Hong
Published in
Obstetrics & gynecology science
To investigate clinical features that affect the number of pelvic lymph nodes (PLNs) harvested and prognostic significance of the number of PLNs removed in patients with stage IB1 to IIA2 cervical cancer. Data from patients with cervical cancer whom underwent hysterectomy with PLN dissection between June 2004 and July 2015 were reviewed retrospecti...
Dursun, Polat Dervisoglu, Haluk Daggez, Mine Turan, Taner Kiliç, Fatih Tekin, Özlem M Üreyen, Işin Toptaş, Tayfun Demirayak, Gökhan Önder, Ayşe B
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Published in
International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics
To report the perioperative outcomes of 200 patients with gynecologic cancer who underwent surgery during the Novel Coronavirus Disease (COVID-19) pandemic and the safety of surgical approach. Data of patients operated between March 10 and May 20, 2020, were collected retrospectively. Data were statistically analyzed using IBM Statistical Package f...
Choi, Hyun-Jin Lee, Yoo-Young Choi, Chel Hun Kim, Tae-Joong Lee, Jeong-Won Bae, Ji Hye Bae, Duk-Soo Kim, Byoung-Gie
Published in
Current problems in cancer
The effectiveness of paclitaxel-cisplatin-ifosfamide triplet regimen (TIP) was reported to be superior to that of paclitaxel-cisplatin doublet. However, the efficacy of paclitaxel-cisplatin-bevacizumab triplet (TPA) and TIP has not been compared. Here, we compared the efficacy and safety of TIP and TPA in patients with metastatic, recurrent, or per...
Woo, Sungmin Atun, Rifat Ward, Zachary J Scott, Andrew M Hricak, Hedvig Vargas, Hebert Alberto
Published in
European radiology
To review the diagnostic performance of contemporary imaging modalities for determining local disease extent and nodal metastasis in patients with newly diagnosed cervical cancer. Pubmed and Embase databases were searched for studies published from 2000 to 2019 that used ultrasound (US), CT, MRI, and/or PET for evaluating various aspects of local e...
Zhang, Y N Li, B Wang, Y T Liu, S H
Published in
Zhonghua fu chan ke za zhi
目的： 探讨腹腔镜子宫广泛性切除术治疗早期子宫颈腺癌的安全性及有效性。 方法： 回顾性分析2007—2017年在中国医学科学院北京协和医学院肿瘤医院接受腹腔镜（腹腔镜组）和开腹（开腹组）子宫广泛性切除术治疗的Ⅰb1~Ⅱa2期［按照国际妇产科联盟（FIGO）2009年的临床分期标准］子宫颈腺癌（包括腺鳞癌）患者，比较两组患者的临床病理特征、手术相关指标及并发症、预后的差异，并分析影响子宫颈腺癌患者预后的因素。 结果： 本研究共纳入293例子宫颈腺癌患者，其中腹腔镜组88例、开腹组205例。（1）临床病理特征：开腹组深间质浸润的比例高于腹腔镜组（分别为38.5%、25.0%），术后辅助治疗的比例也高于腹腔镜组（分别为68.8%、46.6%），两组分别比较，差异均有统计学意义（P0.05）。（2）...
Chen, C L Kang, S Chen, B L Yang, Y Guo, J X Hao, M Wang, W L Ji, M Sun, L X Wang, L
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Published in
Zhonghua fu chan ke za zhi
目的： 比较不同肿瘤直径的Ⅰa1［淋巴脉管间隙浸润（LVSI）阳性］~Ⅰb1期［按照国际妇产科联盟（FIGO 2009）的分期标准］子宫颈癌患者腹腔镜手术与开腹手术的长期肿瘤学结局的差异。 方法： （1）基于中国子宫颈癌临床诊疗大数据项目，纳入2009年1月1日—2016年12月31日符合入组条件的Ⅰa1（LVSI阳性）~Ⅰb1期子宫颈癌患者行腹腔镜手术（腹腔镜组）与开腹手术（开腹组）的患者，进行1∶1倾向性评分匹配（PSM）方法匹配，比较匹配前、后两组患者的肿瘤学结局。（2）将纳入的Ⅰa1（LVSI阳性）~Ⅰb1期子宫颈癌手术患者，进一步根据肿瘤直径的不同分为4层，即肿瘤直径≤1 cm、>1~2 cm、>2~3 cm、>3~4 cm，并在每个分层中分别对腹腔镜与开腹组进行1∶1 PSM方法...
Xu, Y P Wang, Z Q Liang, X D Wang, Y Wang, J L
Published in
Zhonghua fu chan ke za zhi
目的： 比较Ⅰb2~Ⅱa2期子宫颈癌患者行腹腔镜与开腹子宫广泛性切除术的预后差异。 方法： 收集2009年1月1日—2018年12月31日北京大学人民医院10年间收治的Ⅰb2~Ⅱa2期、行腹腔镜或开腹子宫广泛性切除术患者（分别为腹腔镜组、开腹组）的临床病理资料进行回顾性分析，共有237例纳入本研究，其中腹腔镜组115例、开腹组122例，比较两组患者的临床病理特征、手术相关并发症、复发及死亡情况，并对影响复发及死亡的相关因素进行分析。本院腹腔镜手术采取控制CO2气腹压力，经阴道取出子宫标本时尽量避免阴道内肿瘤组织暴露于腹腔中，取出标本后用灭菌注射用水充分冲洗腹腔的无瘤措施。 结果： （1）临床病理特征：腹腔镜组、开腹组患者的年龄、病理类型、病理分级、临床分期、间质浸润深度、淋巴结转移、宫旁浸润...
