Interleukin-6 contributes to initiation of neuronal regeneration program in the remote dorsal root ganglia neurons after...
Published in Histochemistry and cell biology
To assess the potential role of IL-6 in sciatic nerve injury-induced activation of a pro-regenerative state in remote dorsal root ganglia (DRG) neurons, we compared protein levels of SCG-10 and activated STAT3, as well as axon regeneration in IL-6 knockout (IL-6ko) mice and their wild-type (WT) counterparts. Unilateral sciatic nerve compression and...