Itabashi, Michio Bamba, Yoshiko Aihara, Hisako Tani, Kimitaka Nakagawa, Ryousuke Koshino, Kurodo Ohki, Takeshi Ogawa, Shinpei Inoue, Yuji Yamamoto, Masakazu
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Published in
Surgical Case Reports
BackgroundPouch volvulus after proctocolectomy for ulcerative colitis is a very rare postoperative complication. The common site of pouch volvulus has been reported to be the ileal pouch–anal anastomosis and the middle part of the pouch, but no reports on pouch volvulus in the afferent limb of the pouch have been observed. Here, we report the case ...
Jia, Jia Zheng, Kai Shen, Hong Yu, Jiangyi Zhu, Ping Yan, Shihai Xu, Yi Zhu, Lei Lu, Yuelin Gu, Peiqing
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Published in
BMC Complementary Medicine and Therapies
BackgroundThe balance between T helper 17 (Th17) cells and regulatory T cells (Tregs) is involved in immunological tolerance. Destruction of immunological tolerance by dendritic cell (DC)-mediated T cells is involved in the pathogenesis of ulcerative colitis (UC). Qingchang Huashi granule (QCHS) has been confirmed in the treatment of UC involved by...
Bayoumy, Ahmed B. van Liere, Elsa L. S. A. Simsek, Melek Warner, Ben Loganayagam, Aathavan Sanderson, Jeremy D. Anderson, Simon Nolan, Jonathan de Boer, Nanne K. Mulder, Chris J. J.
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Published in
BMC Gastroenterology
BackgroundThioguanine (TG) is a thiopurine which has been used for patients with inflammatory bowel disease (IBD), who have failed azathioprine (AZA) or mercaptopurine (MP) due to adverse events or suboptimal response. Its widespread use has been hampered due to concerns about nodular regenerative hyperplasia (NRH) of the liver. The aim of this stu...
Kostoff, Ronald Neil Briggs, Michael Brandon Shores, Darla Roye
Published in
World Journal of Gastroenterology
Inflammatory bowel disease (IBD) incidence has been increasing steadily, most dramatically in the Western developed countries. Treatment often includes lifelong immunosuppressive therapy and surgery. There is a critical need to reduce the burden of IBD and to discover medical therapies with better efficacy and fewer potential side-effects. Repurpos...
Nøhr, Ellen A Nielsen, Jan Nørgård, Bente M Friedman, Sonia
Published in
Journal of Crohn's & colitis
Previous studies indicate an increased risk of sexual dysfunction in women with inflammatory bowel disease [IBD] but none have examined sexual function in a large population-based cohort. To investigate the risk of sexual dysfunction in women with IBD, we used data from the Danish National Birth Cohort, a nationwide study of 92 274 pregnant women r...
Randall, Jason A. Guobyte, Aiste Delbecque, Laure Newton, Louise Symonds, Tara Hunter, Theresa
Published in
Journal of Patient-Reported Outcomes
BackgroundUlcerative Colitis (UC) is a chronic gastrointestinal disease that often presents during one’s most productive years and is characterized by colon inflammation. Key symptoms and impacts in adults are well-known, however, experiences among pediatric populations have not been well documented. The purpose of this study was to understand the ...
Pan, Hang-Hai Zhou, Xin-Xin Ma, Ying-Yu Pan, Wen-Sheng Zhao, Fei Yu, Mo-Sang Liu, Jing-Quan
Published in
World Journal of Gastroenterology
BACKGROUND Intestinal mucosal barrier dysfunction plays an important role in the pathogenesis of ulcerative colitis (UC). Recent studies have revealed that impaired autophagy is associated with intestinal mucosal dysfunction in the mucosa of colitis mice. Resveratrol exerts anti-inflammatory functions by regulating autophagy. AIM To investigate the...
Yang, Ye Li, Chun-Qiang Chen, Wu-Jie Ma, Zhen-Hua Liu, Gang
Published in
World Journal of Clinical Cases
BACKGROUND Ulcerative colitis (UC) is defined as a chronic inflammatory bowel disease that can occur in any part of the large bowel. In addition, UC affects only the large bowel except for backwash ileitis and pouchitis, whereas Crohn's disease (CD) affects the entire digestive tract. Inflammatory bowel disease (IBD) patients tend to be diagnosed w...
Yang, Hong Wu, Kaichun Zhang, Hongjie Owyang, Qin Miao, Yinglei Gu, Fang Hu, Naizhong Zou, Kaifang Sheng, Jianqiu Li, Jin
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Published in
BMC Gastroenterology
BackgroundCytomegalovirus (CMV) infection can significantly complicate and worsen the condition of acute severe ulcerative colitis (UC) patients. We aimed to explore the predictive risk factors to prevent and identify CMV infection at an early stage in acute UC patients.MethodsA total of 115 moderate-to-severe active UC patients from 17 hospitals t...
Hunt, Melissa G Loftus, Paddy Accardo, Michael Keenan, Mary Cohen, Lauren Osterman, Mark T
Published in
Journal of clinical psychology in medical settings
Patients with inflammatory bowel disease (IBD) often have poor health-related quality of life (HRQL) and are at risk for anxiety and depression. Cognitive behavioral therapy (CBT) can help patients with IBD cope with their disease. Unfortunately, barriers to care include expense and availability of qualified therapists. Stand-alone, self-help CBT c...
