Background: A strong body of research has established stigma as a barrier to care for patients with substance use disorders (SUDs), which can lead to poorer patient outcomes. Prior qualitative research on healthcare practitioners’ perceptions is limited. This study aimed to describe healthcare professional students’ perceived roles in decreasing SU...
Published in Health and quality of life outcomes
Haemophilia is a rare bleeding disorder caused by a deficient or absent clotting factor, leading to frequent bleeding. Multiple intravenous (IV) infusions have been the standard prophylactic treatment; however, newer treatment options involve less frequent subcutaneous (SC) injections. To inform future health economic evaluations, this study applie...
Bacterial meningoencephalitis in newborns is a severe and life-threatening pathology, which results from meningeal infection and the subsequent involvement of the brain parenchyma. The severity of the acute onset of symptoms and the risk of neurodevelopmental adverse sequelae in children strongly depend on the timing of the infection, the immunolog...
Published in Frontiers in Oncology
Background and objective Extrathyroidal extension (ETE) is the term used to describe the growth of the primary thyroid tumor beyond the thyroid capsule. ETE is a critical prognostic marker for thyroid tumors, necessitating accurate preoperative assessment. This study aims to evaluate the diagnostic performance of computed tomography (CT)-based grad...
Thoracic outlet syndrome (TOS) is a group of symptoms caused by the compression of neurovascular structures of the superior thoracic outlet. The knowledge of its clinical presentation with specific symptoms, as well as proper imaging examinations, ranging from plain radiographs to ultrasound, computed tomography and magnetic resonance imaging, may ...
Published in Frontiers in Pharmacology
Background: Pembrolizumab is a potentially valuable treatment. However, patients, doctors, and healthcare decision-makers are uncertain about its cost-effectiveness and an appropriate pricing for this new therapy. This study aims to appraise the cost-effectiveness of pembrolizumab as a first-line treatment for advanced biliary tract cancer (BTC) pa...
Climate change is a significant challenge in today’s world. The construction industry is one of the most energy-intensive and raw material-depleting sectors worldwide. Legal regulations, such as laws, building codes, and alternative governance, are effective ways to help mitigate climate change risks. Most of the research focuses on either one coun...
Parathyroid pathologies are suspected based on the biochemical alterations and clinical manifestations, and the predominant roles of imaging in primary hyperparathyroidism are localisation of tumour within parathyroid glands, surgical planning, and to look for any ectopic parathyroid tissue in the setting of recurrent disease. This article provides...
Europe should avoid entangling in America’s Indo-Pacific strategy and instead focus on the Euro-Atlantic region. Europe does not view China as an equivalent threat to Russia. Europe's primary concerns lie with Ukraine, while the US manages Indo-Pacific security through other alliances. China’s de facto support for Russia in Ukraine poses a greater ...
The proliferation of fake synthetic media has grown exponentially in the past several years. The democratization of artificial intelligence tools propelled the use of deepfake technologies for both progressive and regressive purposes. Similar to fake news, the malicious use of deepfakes is a real threat to the democracy of nations because it can si...
