Cp, Gayathry
Published in
Nutrition and health
Background: High Body Mass Index (BMI) has a two times greater risk of developing type II diabetes compared to low BMI. The results showed that general obesity had a risk of 2.24 times while abdominal obesity had a risk of 2.44 times for the occurrence of diabetes. Aim: Based on the background described, the researcher was interested in examining t...
Eto, Kaoru Itagaki, Rina Takamura, Ayumi Eto, Yoshikatsu Nagata, Satoru
Published in
Molecular genetics and metabolism reports
Neuronal ceroid lipofuscinosis type1(CLN1), is a one form of the group of neuronal ceroid lipofuscinoses (NCLs), which is a neurodegenerative disorder characterized by progressive psychomotor deterioration, ataxia, epilepsy, and visual impairment. Neurological manifestations occur at a wide range of ages, from infancy to adulthood, but are most com...
Woo, Seung-Hwa Choi, Joon Hyuk Mo, Yun Jeong Lee, Yun-Il Jeon, Won Bae Lee, Young-Sam
Published in
Heliyon
Impaired cutaneous wound healing is a major complication in patients with diabetes mellitus (DM), leading to increased amputation and mortality rates in affected patients. Adipose-derived stem cells (ASCs) are widely used seed cells for promoted tissue regeneration to improve wound closure under diabetic conditions. However, ASCs-based therapies re...
Masarone, Daniele Pacileo, Roberta Pacileo, Giuseppe
Published in
Heart failure reviews
Type 2 diabetes mellitus and heart failure are closely related, patients with type 2 diabetes mellitus have a higher risk of developing heart failure, and those with heart failure are at increased risk of developing type 2 diabetes. Although no specific randomized clinical trials have been conducted to test the effect of cardiovascular therapies (d...
Roy, Dipanwita Maity, Narayan Chandra Kumar, Sourav Maity, Anupam Ratha, Bhisma N Biswas, Ranjit Maiti, Nakul Chandra Mandal, Atin Kumar Bhunia, Anirban
Published in
International journal of biological macromolecules
Aggregation of the human islets amyloid polypeptide, or hIAPP, is linked to β-cell death in type II diabetes mellitus (T2DM). Different pancreatic β-cell environmental variables such as pH, insulin and metal ions play a key role in controlling the hIAPP aggregation. Since insulin and hIAPP are co-secreted, it is known from numerous studies that ins...
Sebastian, Sneha Annie Co, Edzel Lorraine Mehendale, Meghana Hameed, Maha
Published in
Disease-a-month : DM
The discovery of insulin by Banting and Best marked 100 years in 2021, and it was a life-saving treatment modality for type II diabetes mellitus (T2DM). Insulin is a natural hormone that has been used extensively in T2DM patients since its discovery. Currently, insulin analogs are also available in different formulations for T2DM management, overco...
Jawad, Shan E Zahra Ibrahim, Muhammad Fatima, Batool Chohan, Tahir Ali Hussain, Dilshad Najam-ul-Haq, Muhammad
Published in
Discover Nano
Metformin (MET) is an anti-diabetic drug employed as the first-line therapy for patients of type II diabetes mellitus (T2DM). Overdosage of drugs leads to severe outcomes, and its monitoring in biofluids is vital. The present study develops cobalt-doped yttrium iron garnets and employs them as an electroactive material immobilized on a glassy carbo...
Pharaboz, Alexandre Kimmoun, Antoine Gunst, Jan Duarte, Kevin Merkling, Thomas Gayat, Etienne Mebazaa, Alexandre Glenn-Chousterman, Benjamin
Purpose: Factors associated with adverse outcomes in ICU patients with type II (T2DM) are poorly defined. The main goal of this study is to determine the impact of pre-existing T2DM on 90-day mortality post ICU admission.Material: Post-hoc analysis from the FROG-ICU cohort. All patients admitted to ICU who were ventilated and/or treated by a vasoac...
Pharaboz, Alexandre; Kimmoun, Antoine; Gunst, Jan; 60237; Duarte, Kevin; Merkling, Thomas; Gayat, Etienne; Mebazaa, Alexandre; Glenn-Chousterman, Benjamin;
PURPOSE: Factors associated with adverse outcomes in ICU patients with type II (T2DM) are poorly defined. The main goal of this study is to determine the impact of pre-existing T2DM on 90-day mortality post ICU admission. MATERIAL: Post-hoc analysis from the FROG-ICU cohort. All patients admitted to ICU who were ventilated and/or treated by a vasoa...
de Souza, Marcele Lorentz Mattos Borçoi, Aline Ribeiro Dutra, Bruna Aparecida Borges Dos Santos Vieira, Tamires Mendes, Suzanny Oliveira Moreno, Ivana Alece Arantes Quaioto, Barbara Risse Olinda, Amanda Sgrancio Cunha, Ester Ribeiro Freitas, Flávia Vitorino
...
Published in
Life sciences
the present study aimed to investigate how glucose and insulin levels may be associated with changes in NR3C1 gene methylation levels in adults. 375 volunteers users of the Brazilian Public Unified Health System (SUS) were recruited to assess socioeconomic status, lifestyle, anthropometric data, blood glucose and serum cortisol levels, insulin resi...
