La tuberculose continue d’être une cause majeure de morbidité et de mortalité dans le monde, principalement dans les pays en voie de développement, bien qu’elle soit une maladie curable. Le diagnostic rapide et précis de la TB active est essentiel pour l’initiation rapide du traitement et le contrôle de la maladie. Le développement de nouveaux test...
ObjectivesBiomarkers for tuberculosis (TB) diagnosis and clinical management are needed to defeat TB. In chronic hepatitis, patients not responding to interferon/ribavirin treatment had high levels of an antagonist form of IP-10. Recently, antagonist IP-10 has been showed to be involved also in TB pathogenesis. Here, we investigated IP-10 agonist/a...
ObjectivesBiomarkers for tuberculosis (TB) diagnosis and clinical management are needed to defeat TB. In chronic hepatitis, patients not responding to interferon/ribavirin treatment had high levels of an antagonist form of IP-10. Recently, antagonist IP-10 has been showed to be involved also in TB pathogenesis. Here, we investigated IP-10 agonist/a...
Biomarkers are increasingly utilised in biological research and clinical practice for diagnosis of disease, monitoring of therapeutic prognosis, or as end points in clinical studies. Cytokines are small molecules that orchestrate immune responses and as such have great potential as biomarkers for both human and veterinary fields. Given the ease of ...
Abstract Background Alcohol and illicit drugs are associated with the discontinuation of tuberculosis (TB) treatment and can compromise the immune system. We estimated the impact of alcohol disorder and the use of illicit drug on TB treatment outcomes, considering the interaction of both substances in patients from São Paulo state, Brazil. Methods ...
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This work was supported by National Council for Scientific and Technological Development (CNPq) from Brazil (141998/2013-0, 202310/2015-9 to JMP and 309647/2015-0 to EAW).
This work was supported by National Council for Scientific and Technological Development (CNPq) from Brazil (141998/2013-0, 202310/2015-9 to JMP and 309647/2015-0 to EAW).
This work was supported by National Council for Scientific and Technological Development (CNPq) from Brazil (141998/2013-0, 202310/2015-9 to JMP and 309647/2015-0 to EAW).
