Wilhelmsson, Peter Jaenson, Thomas G. T. Olsen, Björn Waldenström, Jonas Lindgren, Per-Eric
Published in
Parasites & Vectors
BackgroundBirds can act as reservoirs of tick-borne pathogens and can also disperse pathogen-containing ticks to both nearby and remote localities. The aims of this study were to estimate tick infestation patterns on migratory birds and the prevalence of different Borrelia species and tick-borne encephalitis virus (TBEV) in ticks removed from birds...
Fares, Mazigh Cochet-Bernoin, Marielle Gonzalez, Gaëlle Montero-Menei, Claudia N. Blanchet, Odile Benchoua, Alexandra Boissart, Claire Lecollinet, Sylvie Richardson, Jennifer Haddad, Nadia
...
Published in
Journal of Neuroinflammation
BackgroundTick-borne encephalitis virus (TBEV) is a member of the Flaviviridae family, Flavivirus genus, which includes several important human pathogens. It is responsible for neurological symptoms that may cause permanent disability or death, and, from a medical point of view, is the major arbovirus in Central/Northern Europe and North-Eastern As...
Haviernik, Jan Eyer, Ludek Yoshii, Kentaro Kobayashi, Shintaro Cerny, Jiri Nougairède, Antoine Driouich, Jean-Sélim Volf, Jiri Palus, Martin de Lamballerie, Xavier
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Published in
Antiviral research
The flavivirus, tick-borne encephalitis virus (TBEV) is transmitted by Ixodes spp. ticks and may cause severe and potentially lethal neurological tick-borne encephalitis (TBE) in humans. Studying TBEV requires the use of secondary methodologies to detect the virus in infected cells. To overcome this problem, we rationally designed and constructed a...
Lindqvist, Richard Rosendal, Ebba Weber, Elvira Asghar, Naveed Schreier, Sarah Lenman, Annasara Johansson, Magnus Dobler, Gerhard Bestehorn, Malena Kröger, Andrea
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Published in
Journal of Neuroinflammation
BackgroundTick-borne encephalitis virus (TBEV) is considered to be the medically most important arthropod-borne virus in Europe. The symptoms of an infection range from subclinical to mild flu-like disease to lethal encephalitis. The exact determinants of disease severity are not known; however, the virulence of the strain as well as the immune sta...
Cornelius, Angela D. A. Hosseini, Shirin Schreier, Sarah Fritzsch, David Weichert, Loreen Michaelsen-Preusse, Kristin Fendt, Markus Kröger, Andrea
Published in
Journal of Neuroinflammation
BackgroundTick-borne encephalitis virus (TBEV) is an important human pathogen that can cause the serious illness tick-borne encephalitis (TBE). Patients with clinical symptoms can suffer from severe meningoencephalitis with sequelae that include cognitive disorders and paralysis. While less than 30% of patients with clinical symptoms develop mening...
Marvik, Åshild Tveten, Yngvar Pedersen, Anne-Berit Stiasny, Karin Andreassen, Åshild Kristine Grude, Nils
Published in
Infectious diseases (London, England)
Tick-borne encephalitis (TBE) constitutes a public health concern in Europe. Certain coastal municipalities in southern Norway are considered TBE risk areas and in the last two years, there have been increasing numbers of TBE cases. Since the majority of infections are claimed to be asymptomatic, the aim of the current study was to assess the serop...
Esser, Helen Joan Liefting, Yorick Ibáñez-Justicia, Adolfo van der Jeugd, Henk van Turnhout, Chris A. M. Stroo, Arjan Reusken, Chantal B. E. M. Koopmans, Marion P. G. de Boer, Willem Fred
Published in
Parasites & Vectors
BackgroundArboviruses are a growing public health concern in Europe, with both endemic and exotic arboviruses expected to spread further into novel areas in the next decades. Predicting where future outbreaks will occur is a major challenge, particularly for regions where these arboviruses are not endemic. Spatial modelling of ecological risk facto...
Dueva, Evgenia V Tuchynskaya, Ksenia K Kozlovskaya, Liubov I Osolodkin, Dmitry I Sedenkova, Kseniya N Averina, Elena B Palyulin, Vladimir A Karganova, Galina G
Published in
Antiviral Chemistry & Chemotherapy
Tick-borne encephalitis is an important human arbovirus neuroinfection spread across the Northern Eurasia. Inhibitors of tick-borne encephalitis virus (TBEV) strain Absettarov, presumably targeting E protein n -octyl-β- d -glucoside (β-OG) pocket, were reported earlier. In this work, these inhibitors were tested in vitro against seven strains repre...
Wiesner, Laura Schmutte, Carla Steffen, Imke
Published in
The Journal of infectious diseases
Tick-borne encephalitis virus (TBEV) is a single-stranded, positive-sense RNA virus in the family Flaviviridae that is endemic in parts of Europe and Asia and can cause meningitis or encephalitis. Due to the disease severity, TBEV requires handling under heightened biosafety measures. The establishment and validation of inactivation procedures is a...
Matveev, Andrey Matveev, Leonid Stronin, Oleg Baykov, Ivan Emeljanova, Ljudmila Khlusevich, Yana Tikunova, Nina
Published in
Vaccine
Tick-borne encephalitis virus (TBEV) is the most important tick-transmitted pathogen in the family Flaviviridae and causes one of the most severe human neuroinfections. In this study, a neutralizing mouse mAb 14D5, which was previously shown to have cross-reactive binding to several flaviviruses belonging to the TBEV group, was examined for its pro...
