Alkandari, Abdullah Gujral, Unjali P Bennakhi, Abdullah Qabazard, Sarah Al-Wotayan, Rihab Al Duwairi, Qais Al-Kandari, Hessa Narayan, Km Venkat Alarouj, Monira
Published in
Journal of diabetes investigation
To assess the level of glycemic, blood pressure, and cholesterol control (the 'ABCs') nationally amongst adults with diabetes living in Kuwait. Using data from two national cross-sectional surveys, the levels of risk factor control were assessed in 1,801 adults with diabetes, aged 18-82 years. Glycemic control was defined as HbA1c
Wilding, Anna Munford, Luke Guthrie, Bruce Kontopantelis, Evangelos Sutton, Matt
Published in
Journal of health economics
Healthcare providers may game when faced with targets. We examine how family doctors responded to a temporary but substantial increase in the stringency of targets determining payments for controlling blood pressure amongst younger hypertensive patients. We apply difference-in-differences and bunching techniques to data from electronic health recor...
Carter, Alex B Collier, Catherine Coles, Rob Lawrence, Emma Rasheed, Michael A
Published in
Journal of environmental management
Seagrass habitats provide critical ecosystem services, yet there is ongoing concern over mounting pressures and continuing degradation. Defining a desired state for these habitats is a key step in implementing appropriate management but is often difficult given the challenges of available data and an evaluation of where to set benchmarks. We use mo...
Ge, Jiamin Liu, Zhen Zhong, Zhichao Wang, Liwei Zhuo, Xiaotao Li, Junjie Jiang, Xiaoying Ye, Xiang-Yang Xie, Tian Bai, Renren
...
Published in
Bioorganic chemistry
Natural products are mainly secondary metabolites produced by plants, microorganisms, and animals, which are still abundant in modern drug discovery. Terpenoids are the most diverse group of natural products, attracting extensive attention owing to their various biological activities. This manuscript reviewed the chemical structures, anti-inflammat...
Füzi, Barbara Malik-Sheriff, Rahuman S. Manners, Emma J. Hermjakob, Henning Ecker, Gerhard F.
Published in
Journal of Cheminformatics
As an alternative to one drug-one target approaches, systems biology methods can provide a deeper insight into the holistic effects of drugs. Network-based approaches are tools of systems biology, that can represent valuable methods for visualizing and analysing drug-protein and protein–protein interactions. In this study, a KNIME workflow is prese...
Ma, Rui Kwok, Hang Fai
Published in
Seminars in cancer biology
Due to advances in detection and treatment of cancer, especially the rise in the targeted therapy, the five-year relative survival rate of all cancers has increased significantly. However, according to the analysis of the survival rate of cancer patients in 2019, the survival rate of most cancers is still less than five years. Therefore, to combat ...
Bosso, Giorgio De Luca, Mariarosaria Alma, Giovanni Carbone, Vincenzo Ferrara, Ferdinando Fimiani, Biagio Guarnaccia, Franco Iandolo, Alessandro Murolo, Sabato Olivares, Maurizio
...
Published in
Internal and emergency medicine
The association between LDL-c levels and cardiovascular outcomes suggests tailoring lipid-lowering therapies according to total cardiovascular risk. We aimed to evaluate the adherence to guidelines-oriented dyslipidaemia's treatment in an outpatient population referring to ARCA cardiologists, and assess the efficacy of treatment's optimization for ...
Li, Yuanfeng Liu, Jinyang Zhou, Hongzheng Liu, Juntong Xue, Xiaoying Wang, Longfei Ren, Shujun
Published in
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences
The pharmacological effects and therapeutic targets of naringin (NG) against osteoporosis (OP) is still unclear. Liquid chromatography quadrupole time-of-flight mass spectrometry (LC-Q-TOF/MS) based non-targeted metabonomics has been used to explore the differentiated metabolites and potential biological pathways of NG in the pathological process o...
Ma, Lina Ma, Yongsheng Lian, Ailing
Published in
Pharmacology
Introduction: This study aimed to detect the function of retinoic acid receptor responder 1 (RARRES1) and its regulator miR-769-5p in the growth and mobility of osteosarcoma cells. Methods: The Gene Expression Omnibus database was applied to analyze RARRES1 and miR-769-5p expression, and the survival rate of osteosarcoma patients. The target associ...
Xue, Beibei Chen, Xiaopeng Wang, Xiaoli Li, Chunxia Liu, Jing He, Qiaoyu Liu, Erwei
Published in
Journal of ethnopharmacology
Danggui Liuhuang Tang (DGLHT), first recorded in "Lan-Shi-Mi-Cang" (written in 1276 AD), is a famous classical formula. In 2018, it was listed in the Catalogue of Ancient Classic and Famous Prescriptions (First Batch) formulated by the National Administration of Traditional Chinese Medicine and the National Medical Products Administration. Perimeno...