Pro můj návrh tramvajového obratiště na zastávce Radlická jsem se rozhodl vést tramvajovou smyčku kolem celého bloku. Toto rozhodnutí vychází z úmyslu uvolnit hlavní prostor před budovou ČSOB, která se zde momentálně nachází. Nově uvolněný prostor poblíž metra využívám především k vytvoření parku, který bude ohraničen novou budovou zastávky a podch...
The article presents an analysis of road accidents involving drivers of JSC “GAZEX” vehicles. According to the results of the analysis, the main violations of traffic rules were identified, measures to reduce the number of road accidents were considered. / В статье приведен анализ дорожно-транспортных происшествий с участием водителей транспортных ...
The article discusses the reasons for the occurrence of driver fatigue from vibration that occurs when driving vehicles. The values of permissible resonant frequencies for individual parts of the human body are given. / В статье рассмотрены причины возникновения утомляемости водителей от вибрации, возникающей при движении автотранспортных средств. ...
Published in Inflammation research : official journal of the European Histamine Research Society ... [et al.]
Proper inflammation resolution is crucial to prevent runaway inflammation during sepsis and reduce sepsis-related mortality/morbidity. Previous studies suggest that deleting TRAM, a key TLR4 signaling adaptor, can reprogram the first inflammatory responder cell-neutrophil from an inflammatory state to a resolving state. In this study, we aim to exa...
Published in Journal of plastic, reconstructive & aesthetic surgery : JPRAS
Online resources have become a mainstay for health information, and it is vital that such resources maintain accessible literacy levels to empower informed decision making. Previous studies have shown that the online resources regarding post-mastectomy breast reconstruction are of low readability; however, none have evaluated specific online resour...
Published in Traffic (Copenhagen, Denmark)
Intracellular compartmentalization of ligands, receptors and signaling molecules has been recognized as an important regulator of inflammation. The toll-like receptor (TLR) 2 pathway utilizes the trafficking molecule adaptor protein 3 (AP-3) to activate interleukin (IL)-6 signaling from within phagosomal compartments. To better understand the vesic...
Published in Biology Direct
Toll/Interleukin-1 receptor (TIR) domains are cytoplasmic domain that mediates receptor signalling. These domains are present in proteins like Toll-like receptors (TLR), its signaling adaptors and Interleukins, that form a major part of the immune system. These TIR domain containing signaling adaptors binds to the TLRs and interacts with their TIR ...
Published in Journal of plastic, reconstructive & aesthetic surgery : JPRAS
Published in Aesthetic plastic surgery
Previous data were not conclusive on the safety of gestation in patients whose abdominal flaps were earlier harvested. We performed a meta-analysis to evaluate the abdominal wall complications and birth mode of pregnancy in post-TRAM or post-DIEP harvested individuals. A literature search was performed using the PubMed, Embase, Scopus, and Google s...
Published in Frontiers in Immunology
Pathogenic inflammation and immuno-suppression are cardinal features of exhausted monocytes increasingly recognized in septic patients and murine models of sepsis. However, underlying mechanisms responsible for the generation of exhausted monocytes have not been addressed. In this report, we examined the generation of exhausted primary murine monoc...
