Hamidou, Mohamed Néel, Antoine Poupon, Joel Amoura, Zahir Ebbo, Mikael Sibilia, Jean Viallard, Jean-Francois Gaborit, Benjamin Volteau, Christelle Hardouin, Jean Benoit
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Published in
Arthritis Research & Therapy
BackgroundLupus animal model has shown that arsenic trioxide (ATO), a treatment of acute promyelocytic leukaemia, could be effective in SLE. This is the first clinical study to determine the safety and efficacy of a short course of intravenous ATO in patients with active SLE.MethodsThis phase IIa, open-label, dose-escalating study enrolled 11 adult...
Bay, Pierre Lebreton, Guillaume Mathian, Alexis Demondion, Pierre Desnos, Cyrielle Chommeloux, Juliette Hékimian, Guillaume Bréchot, Nicolas Nieszkowska, Ania Schmidt, Matthieu
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Published in
Annals of Intensive Care
BackgroundSystemic rheumatic diseases (SRDs) are a group of inflammatory disorders that can require intensive care unit (ICU) admission because of multiorgan involvement with end-organ failure(s). Critically ill SRD patients requiring extracorporeal membrane oxygenation (ECMO) were studied to gain insight into their characteristics and outcomes.Met...
Kharbanda, Rajat Mehndiratta, Anurag Chatterjee, Rudrarpan Marak, Rungmei S. K. Aggarwal, Amita
Published in
Clinical Rheumatology
Pulmonary mucormycosis is rare in systemic lupus erythematosus. A 20-year-old lady with lupus nephritis and neuropsychiatric lupus was treated with injection methylprednisolone and cyclophosphamide. After few days, she developed fever, breathlessness, and hoarseness of voice. After neck and chest imaging, possibility of mucormycosis was considered ...
Bashiri, Hamidreza Karimi, Nooshin Mostafaei, Shayan Baghdadi, Azarakhsh Nejadhosseinian, Mohammad Faezi, Seyedeh Tahereh
Published in
BMC Rheumatology
Background Ocular manifestations are common in systemic lupus erythematosus (SLE). Retinopathy has previously been linked to disease severity and might have a significant impact on the patient’s quality of life and has also been associated with a poor prognosis in SLE. This study aimed to determine the prevalence of retinopathy among patients who a...
Nasr, Sandy Khalil, Sara Poiesz, Bernard J. Banki, Katalin Perl, Andras
Published in
Clinical Immunology Communications
We describe a 64-year-old Caucasian female with a history of Raynaud's disease, hand arthritis, photosensitivity, Sjogren's syndrome and leukocytoclastic vasculitis who presented with progressively worsening fingertip necrosis that began three days after receiving a first dose of Pfizer–BioNTech COVID-19 RNA vaccine. Our workup revealed cryoglobuli...
Chen, Long He, Qin Luo, Man Gou, Yuxiao Jiang, Dan Zheng, Xiaoqin Yan, Gaowu He, Fang
Published in
Orphanet Journal of Rare Diseases
Background Lupus enteritis (LEn) is a rare complication of systemic lupus erythematosus (SLE). Timely diagnosis and treatment of LEn are necessary to prevent the most serious consequences — intestinal perforation, gastrointestinal bleeding, and death. We compared the clinical features of SLE patients with and without LEn. Methods The clinical data ...
Li, Xian-Bao Cao, Nv-Wei Chu, Xiu-Jie Zhou, Hao-Yue Wang, Hua Yu, Si-Jie Ye, Dong-Qing Li, Bao-Zhu
Published in
Annals of Medicine
Objective To investigate the effect of antimalarials on cancer risk in patients with systemic lupus erythematosus (SLE). Methods PubMed, EMBASE, Web of Science, and the Cochrane Library were searched from their inception to October 3, 2020. Relative risk (RR) with 95% confidence intervals (CI) was used to evaluate the results. Subgroup analyses wer...
Chiruvolu, Neha V. Safarpour, Yasaman Sandhu, Vaneet K.
Published in
Journal of Community Hospital Internal Medicine Perspectives
The aim of this study is to identify rheumatology practice care gaps in evaluating for vitamin D deficiency in systemic lupus erythematosus (SLE), as well as adherence to vitamin D replacement in SLE patients currently on corticosteroid therapy. Data for this study were collected from the Southern California Lupus Registry in addition to data extra...
Guillaume, Debellemanière Magalie, Bouvet Sina, Elahi Imène, Salah-Mabed Frédéric, Vayr Mathieu, Dubois Aurore, Muselier Yoni, Gozlan Emma, Elbaz Charlotte, Badatcheff
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Published in
Rheumatology and Therapy
Introduction We aimed to study the prevalence of a history of COVID-19 infection among patients suffering from systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), Sjögren’s syndrome (SjS) or psoriatic arthritis (PsA), and the potential influence of long-term hydroxychloroquine (HCQ) intake. Methods We performed an observational monocentr...
Marklein, Bianka Jenning, Madeleine Konthur, Zoltán Häupl, Thomas Welzel, Franziska Nonhoff, Ute Krobitsch, Sylvia Mulder, Debbie M. Koenders, Marije I. Joshua, Vijay
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Published in
Arthritis Research & Therapy
Background There is a need for biomarker to identify patients “at risk” for rheumatoid arthritis (risk-RA) and to better predict the therapeutic response and in this study we tested the hypothesis that novel native and citrullinated heterogeneous nuclear ribonucleoprotein (hnRNP)-DL autoantibodies could be possible biomarkers. Methods Using protein...
