Current methods for disease detection, such as traditional tissue and liquid biopsies, often face challenges related to invasiveness, limited sensitivity, and lengthy procedures, which can impede early diagnosis and effective treatment. Surface-Enhanced Raman Spectroscopy (SERS) offers a promising alternative due to its non-invasive nature, high se...
Published in Asian journal of surgery
Perianal fistulising Crohn's disease (PFCD) is different from the characteristics and outcomes of traditional non-inflammatory bowel disease (IBD) anal fistulas. The presence of perianal disease was a poor prognostic indicator for Crohn's disease (CD) patients and PFCD patients were more likely to bear an increased risk of recurrence. However, the ...
Published in Talanta
Since there is no effective Alzheimer's disease (AD)-modifying therapy available currently, early analysis of AD core biomarkers has become one of great significance and common concern in clinical diagnosis. Herein, we designed an Au-plasmonic shell attached polystyrene (PS) microsphere in a microfluidic chip for simultaneous detection of Aβ1-42 an...
La spectroscopie Raman est une technique d'analyse rapide, spécifique et non destructive qui permet d'analyser un grand nombre de molécules par la mesure de leurs énergies de vibration. Cependant, la faible proportion de photons diffusés en diffusion Raman (1 sur 108) limite son usage à l'analyse de molécules dont les concentrations sont de l'ordre...
Published in Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
This study aimed to develop and validate a simple and efficient surface-enhanced Raman spectroscopy (SERS) method to determine flunixin meglumine (FM) residues in animal tissues through using core-shell Au@MIL-100 (Fe) as enhanced substrate. Au@MIL-100 (Fe) composite material was synthesized by coating metal-organic framework materials (MOFs) on th...
Published in Heliyon
Corneal cross-linking (CXL) with riboflavin and ultraviolet A light is a therapeutic procedure to restore the mechanical stability of corneal tissue. The treatment method is applied to pathological tissue, such as keratoconus and induces the formation of new cross-links. At present, the molecular mechanisms of induced cross-linking are still not kno...
Published in Applied spectroscopy
Surface enhanced Raman spectroscopy (SERS) has evolved into a powerful analytical method in food and environmental analytical sciences due to its high sensitivity. Pesticide analysis is a major discipline therein. Using sustainable materials has become increasingly important to adhere to Green Chemistry principles. Hence, the green textiles poly-(L...
Published in Nano letters
Surface-enhanced coherent anti-Stokes Raman scattering (SE-CARS) takes advantage of surface plasmon resonances supported on metallic nanostructures to amplify the coherent Raman response of target molecules. While these metallic antennas have found significant success in SE-CARS studies, photoinduced morphological changes to the nanoantenna under u...
The design of smart hydrogel particles doped with plasmonic nanoparticles has attracted great in-terest in recent years due to their promising outlook in nanomedicine as therapeutic systems and bioimag-ing agents. Nanocomposite microgels were found particularly interesting as contrast agents for photoacoustic imaging (PAI), an emerging noninvasive ...
Published in Biosensors & bioelectronics
The detection of cancer cells at the single-cell level enables many novel functionalities such as next-generation cancer prognosis and accurate cellular analysis. While surface-enhanced Raman spectroscopy (SERS) has been widely considered as an effective tool in a low-cost and label-free manner, however, it is challenging to discriminate single can...
