De Pretto-Lazarova, Angela Brancati-Badarau, Domnita Oana Burri, Christian
Published in
BMC Public Health
BackgroundStandardised checklists of items to be addressed in clinical study protocols and publications are promoting transparency in research. However, particular specifications for exceptional cases, such as children with minor parents are missing. This study aimed to examine the level of transparency regarding recruitment and informed consent ap...
Nambafu, Jamila Achakolong, Mary Mwendwa, Fridah Bwika, Jumaa Riunga, Felix Gitau, Samuel Patel, Hanika Adam, Rodney D.
Published in
BMC Infectious Diseases
BackgroundLower respiratory tract infections continue to contribute significantly to morbidity and mortality across all age groups globally. In sub-Saharan Africa, many studies of community acquired pneumonia in adults have focused on HIV-infected patients and little attention has been given to risk factors and etiologic agents in an urban area wit...
Ifeanyichi, Martilord Broekhuizen, Henk Cheelo, Mweene Juma, Adinan Mwapasa, Gerald Borgstein, Eric Kachimba, John Gajewski, Jakub Brugha, Ruairi Pittalis, Chiara
...
Published in
BMC Health Services Research
BackgroundAn estimated nine out of ten persons in sub-Saharan Africa (SSA) are unable to access timely, safe and affordable surgery. District hospitals (DHs) which are strategically located to provide basic (non-specialist) surgical care for rural populations have in many instances been compromised by resource inadequacies, resulting in unduly freq...
Esterhuizen, Tonya M. Li, Guowei Young, Taryn Zeng, Jie Machekano, Rhoderick Thabane, Lehana
Published in
Trials
BackgroundSub-Saharan Africa continues to carry a high burden of communicable diseases such as TB and HIV and non-communicable diseases such as hypertension and other cardiovascular conditions. Although investment in research has led to advances in improvements in outcomes, a lot still remains to be done to build research capacity in health. Like m...
Reed, Domonique M. Esber, Allahna L. Crowell, Trevor A. Ganesan, Kavitha Kibuuka, Hannah Maswai, Jonah Owuoth, John Bahemana, Emmanuel Iroezindu, Michael Ake, Julie A.
...
Published in
AIDS Research and Therapy
BackgroundPersons living with HIV (PLWH) who are members of sero-discordant and sero-concordant relationships may experience psychological stressors or motivators that affect HIV care. We assessed the association between sero-discordance status, antiretroviral therapy (ART) uptake, and viral suppression in the African Cohort Study (AFRICOS).Methods...
Edem, Bassey Onwuchekwa, Chukwuemeka Wariri, Oghenebrume Nkereuwem, Esin Nkereuwem, Oluwatosin O. Williams, Victor
Published in
Trials
ObjectiveProspective registration of clinical trials is an ethical, scientific, and legal requirement that serves several functions, including minimising research wastage and publication bias. Sub-Saharan Africa (SSA) is increasingly hosting clinical trials over the past few years, and there is limited literature on trends in clinical trial registr...
Villegas, Ana C. Saylor, Deanna Kvalsund, Michelle Atadzhanov, Masharip Chiluba, Clarence Chishimba, Lorraine Zimba, Stanley Chomba, Mashina Siddiqi, Omar K.
Published in
Human Resources for Health
ObjectiveTo investigate opportunities for task shifting to decongest an outpatient neurology clinic in Zambia by describing current patient flow through the clinic and potential nodes for intervention using process mapping.BackgroundZambia has a population of approximately 18 million people with 4 full-time adult neurologists, as of 2018, who all p...
Schue, Jessica L. van Dijk, Janneke H. Hamangaba, Francis Hamahuwa, Mutinta Moyo, Nkumbula Thuma, Philip E. Moss, William J. Sutcliffe, Catherine G.
Published in
BMC Pediatrics
BackgroundHIV testing and treatment guidelines for children in sub-Saharan Africa have evolved over time, such that children are now treated at younger ages. The objective of this study was to describe the treatment experience for immunologic, virologic, and growth outcomes among HIV-infected Zambian children younger than 5 years of age from 2008 t...
Akena, Dickens Kiguba, Ronald Muhwezi, Wilson W. Kwesiga, Brendan Kigozi, Gwendolyne Nakasujja, Noeline Lukwata, Hafsa
Published in
Trials
BackgroundLiterature shows a high prevalence of psychological distress (PD) as well as common mental disorders (CMD) such as major depressive disorders (MDD), generalized anxiety disorders (GAD), post-traumatic stress disorders (PTSD), and substance misuse disorders (SUD) among people exposed to disasters and pandemics like the COVID-19. Moreover, ...
Beckham, S. Wilson Stockton, Melissa Galai, Noya Davis, Wendy Mwambo, Jessie Likindikoki, Samuel Kerrigan, Deanna
Published in
BMC Public Health
BackgroundFemale sex workers in sub-Saharan Africa face high unmet need for family planning and higher risk for unintended pregnancy. Community empowerment HIV prevention approaches have the potential to increase family planning uptake and present an opportunity to integrate HIV, reproductive health, and contraception. This article describes family...
