Matsushima, Asako Kuroki, Yuichi Nakajima, Shinji Kojima, Hiroki Seki, Tadahiko Ueyama, Masashi
Published in
Burns : journal of the International Society for Burn Injuries
Among adult and pediatric patients, concern is growing in regard to toxic shock syndrome (TSS) resulting from methicillin-resistant Staphylococcus aureus (MRSA) nosocomial infection. We investigated the incidence and characteristics of this form of TSS in patients with burn injury who were admitted to our burn care units from January 2008 to Decemb...
Pinilla, Carlos A. López, Ángela M. Gálvez, Andrés F. Corpas, Eduardo J. Rosero-Moreano, Milton Stashenko, Elena E.
Novel and miniaturized technique, a dynamic sonication-assisted solvent extraction before the analysis by high performance liquid chromatography-ultraviolet visible (HPLC-UV-Vis) for isolation, identification and quantification of rutin and quercetin metabolites in alcoholic extracts from Bidens pilosa Linné, was developed. The results showed that ...
Abotsi, Regina E. Nicol, Mark P. McHugh, Grace Simms, Victoria Rehman, Andrea M. Barthus, Charmaine Mbhele, Slindile Moyo, Brewster W. Ngwira, Lucky G. Mujuru, Hilda
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Published in
BMC Infectious Diseases
Background HIV-associated chronic lung disease (CLD) is common among children living with HIV (CLWH) in sub-Saharan Africa, including those on antiretroviral therapy (ART). However, the pathogenesis of CLD and its possible association with microbial determinants remain poorly understood. We investigated the prevalence, and antibiotic susceptibility...
Song, Jun Ruan, Hongri Chen, Li Jin, Yuqi Zheng, Jiasan Wu, Rui Sun, Dongbo
Published in
BMC Microbiology
Background Staphylococcus aureus is the causative agent of chronic mastitis, and can form a biofilm that is difficult to completely remove once formed. Disinfectants are effective against S. aureus , but their activity is easily affected by environmental factors and they are corrosive to equipment and chemically toxic to livestock and humans. There...
Liu, Aibo Yo, Chia-Hung Nie, Lu Yu, Hua Wu, Kuihai Tong, Hoi Sin Hsu, Tzu-Chun Hsu, Wan-Ting Lee, Chien-Chang
Published in
BMC Infectious Diseases
Background The association between blood culture status and mortality among sepsis patients remains controversial hence we conducted a tri-center retrospective cohort study to compare the early and late mortality of culture-negative versus culture-positive sepsis using the inverse probability of treatment weighting (IPTW) method. Methods Adult pati...
Huemer, Markus Mairpady Shambat, Srikanth Bergada-Pijuan, Judith Söderholm, Sandra Boumasmoud, Mathilde Vulin, Clément Gómez-Mejia, Alejandro Antelo Varela, Minia Tripathi, Vishwachi Götschi, Sandra
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Published in
Proceedings of the National Academy of Sciences of the United States of America
Staphylococcus aureus causes invasive infections and easily acquires antibiotic resistance. Even antibiotic-susceptible S. aureus can survive antibiotic therapy and persist, requiring prolonged treatment and surgical interventions. These so-called persisters display an arrested-growth phenotype, tolerate high antibiotic concentrations, and are asso...
Reddy, Kessendri Whitelaw, Andrew
Published in
BMC Infectious Diseases
Background Positive blood cultures showing Gram positive cocci in clusters signifies either Staphylococcus aureus or the less-virulent coagulase-negative staphylococci. Rapid identification and methicillin susceptibility determination with the Xpert MRSA/SA BC assay can improve management of S. aureus bloodstream infection and reduce inappropriate ...
Gimza, Brittney D. Cassat, James E.
Published in
Frontiers in Immunology
Staphylococcus aureus is a highly successful Gram-positive pathogen capable of causing both superficial and invasive, life-threatening diseases. Of the invasive disease manifestations, osteomyelitis or infection of bone, is one of the most prevalent, with S. aureus serving as the most common etiologic agent. Treatment of osteomyelitis is arduous, a...
McClure, Jo-Ann Lakhundi, Sahreena Niazy, Amani Dong, George Obasuyi, Osahon Gordon, Paul Chen, Sidong Conly, John M. Zhang, Kunyan
Published in
Frontiers in Microbiology
Despite initially being described in North America, Staphylococcus aureus (SA) sequence type ST59 is the most commonly isolated sequence type in Eastern Asia. The origins and evolution of this strain type remains unclear and therefore we gathered a collection of ST59 isolates from Canada and mainland China for a detailed genetic analysis of the lin...
Cruz, Ana Rita den Boer, Maurits A. Strasser, Jürgen Zwarthoff, Seline A. Beurskens, Frank J. de Haas, Carla J. C. Aerts, Piet C. Wang, Guanbo de Jong, Rob N. Bagnoli, Fabio
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Published in
Proceedings of the National Academy of Sciences of the United States of America
Immunoglobulin (Ig) G molecules are essential players in the human immune response against bacterial infections. An important effector of IgG-dependent immunity is the induction of complement activation, a reaction that triggers a variety of responses that help kill bacteria. Antibody-dependent complement activation is promoted by the organization ...