Published in Updates in surgery
Laparoscopic splenectomy in the case of massive or supermassive splenomegaly has been associated with higher conversion rates and morbidity. The purpose of our study is to evaluate the feasibility and safety of laparoscopic splenectomy for massive spleens and to identify if there are limits beyond which the laparoscopic approach is not recommended ...
Published in Journal of vascular surgery
Splenectomy is often performed during open thoracoabdominal aortic aneurysm (TAAA) repair, because capsular tears are common and can be associated with significant bleeding. It is unknown whether splenectomy affects the short- or long-term outcomes after TAAA repair. All open type I to IV TAAA repairs performed from 1987 to June 2015 were evaluated...
Published in The American Journal of Case Reports
Patient: Female, 38-year-old Final Diagnosis: Coagulopathy • splenic marginal zone lymphoma Symptoms: Abdominal swelling • early satiety Medication: — Clinical Procedure: Splenectomy Specialty: Hematology Objective: Rare disease Background: Here, we report the novel presentation of a factor VII inhibitor in association with a new diagnosis of splen...
Published in International journal of surgery case reports
Splenic pseudocysts are extremely uncommon. Most of these cysts are asymptomatic and may result from previous blunt abdominal trauma. We report an interesting uncommon case of large splenic pseudocyst without history of previous abdominal trauma. A 56 year old male patient, presented with symptoms of pain in the left side of middle back and discomf...
Published in The Journal of surgical research
Splenic injury is common in blunt trauma. We sought to evaluate the injury characteristics and outcomes of BSI admitted over a 10-y period to an academic trauma center. A retrospective review of adult blunt splenic injury patients admitted between January 2009 and September 2018. The 423 patients meeting inclusion criteria were divided by managemen...
Published in International journal of surgery case reports
Among the various causes for lower gastrointestinal bleeding, ectopic varices constitute a small chunk. Though rare, these can pose a diagnostic challenge with recurrent bleed leading to multiple admission and blood transfusions. A 41-year-old male presented to our department with multiple episodes of melena. On further evaluation with CT angiograp...
Published in Journal of Ovarian Research
Background To investigate changes in peripheral lymphocyte subsets after splenectomy during cytoreductive surgery for advanced or recurrent ovarian cancers. Methods We enrolled 83 patients with advanced or recurrent ovarian cancer who underwent cytoreductive surgery. Twenty patients who also underwent splenectomy were assigned to the splenectomy co...
Published in Turkish Journal of Hematology
Objective: Primary immune thrombocytopenia (ITP) is an acquired autoimmune disease characterized by isolated thrombocytopenia. While first-line treatments focus on inhibiting autoantibodies and platelet destruction, second- and third-line treatments include splenectomy and thrombopoietin receptor agonists. In this study, we aimed to compare the eff...
Published in American Journal of Blood Research
Background: Immune Thrombocytopenia (ITP) is characterized by low platelet counts. Splenectomy has been in practice for the treatment of ITP since the early 20th century. We aimed to analyze the data of ITP patients from our hospital who underwent splenectomy and further present the long-term outcome and safety profile in these patients. Method: Th...
Published in American Journal of Translational Research
Evidence suggests that immune dysfunction exerts a central role in the morbidity and mortality of sepsis. As the spleen is the largest lymphatic tissue in the body, its influence on immune regulation during sepsis should be explored. In this study, we analysed the immune alterations of the spleen of septic rats and the effects of splenectomy at 6 h...
