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Gao, Kai Niu, Jianbing Dang, Xiaoqian
Published in
Neuroscience letters
Little is known about the effect of wnt-3a on motor nerve function and its specific molecular mechanisms after spinal cord injury (SCI). This study demonstrates that the downregulated expression levels of caspases-3, caspases-9 and chondroitin sulfate proteoglycan (CSPG) proteins and number of proportion of transferase UTP nick end labeling (TUNEL)...
Li, Jinquan Chen, Gong Gao, Xinjie Shen, Chao Zhou, Ping Wu, Xing Che, Xiaoming Xie, Rong
Published in
Neuroscience letters
Spinal cord ischemia-reperfusion (I/R) injury is a severe clinical condition, while the mechanism is still not clarified and the therapeutic approach is limited. Ischemia post-conditioning (PC) has been found to have the protective effects against I/R injury in brain. Recently p53 has been reported to take part in the regulation and protection of I...
Zhang, L Hsu, F-C Mojsilovic-Petrovic, J Jablonski, A M Zhai, J Coulter, D A Kalb, R G
Published in
Molecular and cellular neurosciences
Activation of AMPA receptors assembled with the GluA1 subunit can promote dendrite growth in a manner that depends on its direct binding partner, SAP97. SAP97 is a modular scaffolding protein that has at least seven recognizable protein-protein interaction domains. Several complementary approaches were employed to show that the dendrite branching p...
Jiang, Frank Xue Lin, David C. Horkay, Ferenc Langrana, Noshir A.
Published in
Annals of Biomedical Engineering
In this study, we describe the design and initial results of probing mechanical adaptation of neurite growth of lightly fixed neurons on a hydrogel substrate by using atomic force microscopy (AFM). It has been shown previously that cells are responsive to the physical conditions of their micro-environment, and that certain cells can adjust their ow...
