Yamada, Chiaki Maeda, Aiko Matsushita, Katsuyuki Nakayama, Shoko Shirozu, Kazuhiro Yamaura, Ken
Published in
JA Clinical Reports
BackgroundPatients with spinal cord injury (SCI) frequently complain of intractable pain that is resistant to conservative treatments. Here, we report the successful application of 1-kHz high-frequency spinal cord stimulation (SCS) in a patient with refractory neuropathic pain secondary to SCI.Case presentationA 69-year-old male diagnosed with SCI ...
Morio, Atsushi Miyoshi, Hirotsugu Saeki, Noboru Toyota, Yukari Tsutsumi, Yasuo M.
Published in
JA Clinical Reports
BackgroundAcute onset paraplegia after endovascular aneurysm repair (EVAR) is a rare but well-known complication. We here show a 79-year-old woman with paraplegia caused by static and dynamic spinal cord insult not by ischemia after EVAR.Case presentationThe patient underwent EVAR for abdominal aortic aneurism under general anesthesia in the supine...
Naga, Ashraf N El Tavolaro, Celeste Agel, Julie Zhou, Haitao Bellabarba, Carlo Bransford, Richard J
Published in
The spine journal : official journal of the North American Spine Society
Thoracic costotransversectomies (TCT) are amongst the most invasive spine procedures performed. Of greatest concern to the patient and surgeon is the risk of iatrogenic neurologic injury associated with these procedures. Most available studies limit their assessment of neurologic function to nonspecific scales such as the broader ASIA scoring syste...
Li, Yao Zhang, Jing Zhou, Kailiang Xie, Ling Xiang, Guangheng Fang, Mingqiao Han, Wen Wang, Xiangyang Xiao, Jian
Published in
Cell biology and toxicology
Spinal cord injury (SCI) is a devastating neurological trauma that causes losses of motor and sensory function. Sestrin2, also known as hypoxia inducible gene 95, is emerging as a critical determinant of cell homeostasis in response to cellular stress. However, the role of sestrin2 in the neuronal response to endoplasmic reticulum (ER) stress and t...
He, Yu-Qi Shi, Xue-Xing Chen, Li Zhao, Wen-Bo Shan, Jing Lin, Zong-Long Yang, Lei-Luo Li, Qing
Published in
The International journal of neuroscience
To explore the relationship between cerebrospinal fluid-contacting neurons (CSF-cNs) and endogenous neural progenitor cells (ENPCs) and whether CSF-cNs are involved in nerve repair after spinal cord injury (SCI). Cholera toxin B-horseradish peroxidase complex (CB-HRP) and cholera toxin B conjugated with saporin (CB-SAP) were injected into the later...
Krhut, Jan Wohlfahrt, Peter Pudich, Jiří Kufová, Eliška Borovička, Vladimír Bílková, Karolína Sýkora, Radek Mokriš, Jan Cífková, Renata Zachoval, Roman
...
Published in
International urology and nephrology
To analyze cardiovascular safety of mirabegron in patients with spinal cord injury (SCI)- and multiple sclerosis (MS)-induced neurogenic detrusor overactivity (NDO) in a prospective, randomized, double-blind, placebo-controlled study. Seventy-eight patients were enrolled into the study, and 66 of them were included into the final analysis. In 49 (7...
Xue, Weiwei Zhang, Haipeng Fan, Yongheng Xiao, Zhifeng Zhao, Yannan Liu, Weiyuan Xu, Bai Yin, Yanyun Chen, Bing Li, Jiayin
...
Published in
Stem Cell Research & Therapy
BackgroundMicrotubule-stabilizing agents have been demonstrated to modulate axonal sprouting during neuronal disease. One such agent, Epothilone D, has been used to treat spinal cord injury (SCI) by promoting axonal sprouting at the lesion site after SCI. However, the role of Epothilone D in the differentiation of neural stem cells (NSCs) in SCI re...
Buxbaum, Rina E. Shani, Adi Mulla, Hani Rod, Alon Rahamimov, Nimrod
Published in
Journal of Orthopaedic Surgery and Research
IntroductionFractures in the ankylotic spine may have an insidious presentation but are prone to displace with devastating consequences. The long lever arm of ankylosed spine fragments may lead to pulmonary and great vessel injury and is difficult to adequately immobilize. Conservative treatment will produce in many cases poor outcomes with high mo...
Li, Jing Li, Heyangzi Cai, Simin Bai, Shi Cai, Huabo Zhang, Xiaoming
Published in
Stem Cell Research & Therapy
BackgroundRecent studies demonstrated that autologous mitochondria derived from bone marrow mesenchymal stem cells (BMSCs) might be valuable in the treatment of spinal cord injury (SCI). However, the mechanisms of mitochondrial transfer from BMSCs to injured neurons are not fully understood.MethodsWe modified BMSCs by CD157, a cell surface molecule...
All, Angelo H Luo, Shiyu Liu, Xiaogang Al-Nashash, Hasan
Published in
Brain research bulletin
In this paper, we investigate the forelimbs somatosensory evoked potential (SSEP) signals, which are representative of the integrity of ascending sensory pathways and their stability as well as function, recorded from corresponding cortices, post thoracic spinal cord injury (SCI). We designed a series of distinctive transection SCI to investigate w...
