McMillan, David W Kressler, Jochen Jacobs, Kevin A Nash, Mark S
Published in
European journal of applied physiology
Whole body energy expenditure and lipid oxidation (Lox) are upregulated during and after exercise. Persons with spinal cord injury (SCI) generally have a blunted ability to utilize fat during exercise, but it is unknown if their substrate partitioning is affected during recovery from exercise. To determine the effect of a single session of upper bo...
Lienkämper, Robin Dyck, Susanne Saif-ur-Rehman, Muhammad Metzler, Marita Ali, Omair Klaes, Christian
Published in
Scientific Reports
Invasive brain–computer-interfaces (BCIs) aim to improve severely paralyzed patient’s (e.g. tetraplegics) quality of life by using decoded movement intentions to let them interact with robotic limbs. We argue that the performance in controlling an end-effector using a BCI depends on three major factors: decoding error, missing somatosensory feedbac...
Zulauf-Czaja, Anna Al-Taleb, Manaf K. H. Purcell, Mariel Petric-Gray, Nina Cloughley, Jennifer Vuckovic, Aleksandra
Published in
Journal of NeuroEngineering and Rehabilitation
Background Regaining hand function is the top priority for people with tetraplegia, however access to specialised therapy outwith clinics is limited. Here we present a system for hand therapy based on brain-computer interface (BCI) which uses a consumer grade electroencephalography (EEG) device combined with functional electrical stimulation (FES),...
Wang, Chenjian Xu, Tianzhen Lachance, Brittany Bolduc Zhong, Xiqiang Shen, Guangjie Xu, Tao Tang, Chengxuan Jia, Xiaofeng
Published in
Journal of Neuroinflammation
Background The pathological process of traumatic spinal cord injury (SCI) involves excessive activation of microglia leading to the overproduction of proinflammatory cytokines and causing neuronal injury. Sphingosine kinase 1 (Sphk1), a key enzyme responsible for phosphorylating sphingosine into sphingosine-1-phosphate (S1P), plays an important rol...
Wang, Juncheng Zhao, Yin Tang, Yifan Li, Fengning Chen, Xiongsheng
Published in
American Journal of Translational Research
Spinal cord injury (SCI) is an insult to the spinal cord resulting in a change, either temporary or permanent, in its normal motor or sensory function, but the mechanism of neuron loss after spinal cord injury is still unclear. Long non-coding RNAs (lncRNAs) can play an important role in regulating cell physiological activities through competitivel...
Yoshida, Ryo Tomita, Kazuhide Kawamura, Kenta Setaka, Yukako Ishii, Nobuhisa Monma, Masahiko Mutsuzaki, Hirotaka Mizukami, Masafumi Ohse, Hirotaka Imura, Shigeyuki
...
Published in
Journal of Physical Therapy Science
[Purpose] The respiratory function in patients with cervical spinal cord injury is influenced by inspiratory intercostal muscle function. However, inspiratory intercostal muscle activity has not been conclusively evaluated. We evaluated the inspiratory intercostal muscle activity in patients with cervical spinal cord injury by using inspiratory int...
Wang, Yang Lai, Xunwei Wu, Depeng Liu, Bin Wang, Nanxiang Rong, Limin
Published in
Stem Cell Research & Therapy
Background Although exosomes, as byproducts of human umbilical cord mesenchymal stem cells (hUC-MSCs), have been demonstrated to be an effective therapy for traumatic spinal cord injury (SCI), their mechanism of action remains unclear. Methods We designed and performed this study to determine whether exosomes attenuate the lesion size of SCI by ame...
Maki, Satoshi Kitamura, Mitsuhiro Furuya, Takeo Miyamoto, Takuya Okimatsu, Sho Shiga, Yasuhiro Inage, Kazuhide Orita, Sumihisa Eguchi, Yawara Ohtori, Seiji
...
Published in
BMC musculoskeletal disorders
According to most of the commonly used classification systems for subaxial spine injuries, unilateral and minimally displaced facet fractures without any sign of a spinal cord injury would be directed to non-operative management. However, the failure rate of non-operative treatment varies from 20 to 80%, and no consensus exists with regard to predi...
Liu, Wen-zhao Ma, Zhan-jun Li, Jie-ru Kang, Xue-wen
Published in
Stem Cell Research & Therapy
Spinal cord injury (SCI) often leads to serious motor and sensory dysfunction of the limbs below the injured segment. SCI not only results in physical and psychological harm to patients but can also cause a huge economic burden on their families and society. As there is no effective treatment method, the prevention, treatment, and rehabilitation of...
Triplet, Erin M. Scarisbrick, Isobel A.
Published in
Spinal Cord Series and Cases
Study designWe completed retrospective analysis of statin use in individuals with neurologically significant spinal cord injury in a historical cohort study.ObjectiveOur objective was to establish the prevalence of cholesterol-lowering agent use following spinal cord injury (SCI) and to determine the impact on recovery of motor function.SettingPati...
