Ding, Lin-Fen Hu, Guo-Xian Liu, Yu-Yao Wang, Qiu-Hua Li, Zhang-Juan Shen, Meng-Xia Zhu, Gui-Fa Wu, Xing-De Su, Jia
Published in
Phytochemistry
Five undescribed eudesmane sesquiterpenoids, artemilavanins A-E, and one undescribed rearranged eudesmane sesquiterpenoid, artemilavanin F, were isolated from the 95% ethanol extract of the aerial parts of Artemisia lavandulaefolia DC., along with ten known compounds. The structures and configurations of undescribed compounds were mainly elucidated...
Yao, Zongwen Chen, Lin Hu, Min Meng, Fancheng Chen, Min Wang, Guowei
Published in
Bioorganic chemistry
FXR agonistic activity screening was conducted based on natural product resources containing 38 structurally diverse sesquiterpenoids isolated from Xylopia vielana. Among them, 34 undescribed sesquiterpenoids with 5 different skeleton types were first characterized by HRESIMS, NMR data, ECD calculations and X-ray crystallographic analysis. High-con...
Vaillant, Fabrice Llano, Sandra Ángel Martín, Alberto Moreno-Castellanos, Natalia
Published in
Food research international (Ottawa, Ont.)
The metabolites entering the bloodstream and being excreted in urine as a result of consuming golden berries are currently unidentified. However, these metabolites potentially underlie the health benefits observed in various in vitro, animal, and human models. A nutritional intervention with 18 healthy human volunteers was performed, and urine was ...
Li, De-Sen Shi, Lin-Lin Guo, Kai Luo, Shi-Hong Liu, Yan-Chun Chen, Yue-Gui Liu, Yan Li, Sheng-Hong
Published in
Phytochemistry
The sesquiterpene β-bisabolene possessing R and S configurations is commonly found in plant essential oils with antimicrobial and antioxidant activities. Here, we report the cloning and functional characterization of a (R)-β-bisabolene synthase gene (CcTPS2) from a Lamiaceae medicinal plant Colquhounia coccinea var. mollis. The biochemical function...
Zhang, Juan Yang, Fang-Yu Zhu, Qi-Meng Zhang, Wen-Hao Zhang, Min Yi, Jing Wang, Yan Zhang, Hou-Li Yan, Jian-Kun Liang, Guo-Biao
...
Published in
International journal of biological macromolecules
Soluble epoxide hydrolase (sEH) serves as a potential target in inflammation-related diseases. Based on the bioactivity-guided separation, a new sesquiterpenoid inulajaponoid A (1) was isolated from Inula japonica with a sEH inhibitory effect, together with five known compounds, such as 1-O-acetyl-6-O-isobutyrylbritannilactone (2), 6β-hydroxytoment...
Joshi, Rajesh K
Published in
Natural product research
The hydro-distillation essential oil was obtained from the leaf, stem, and flower of Blumea paniculata (Willd.) M.R.Almeida (Asteraceae) and analysed using gas chromatography equipped with a flame ionisation detector (GC-FID) and gas chromatography coupled with mass spectrometry (GC-MS). Fifty-eight, sixty-nine and, fifty-seven constituents were id...
Chen, Zhenhao Sun, Yunpeng Wang, Yongyue Kong, Lingyi Luo, Jun
Published in
Natural product research
Two new sesquiterpenoids, sarglanoids G and H (1 and 2), together with two known analogues (3-4) were isolated from the roots of Sarcandra glabra. Compound 2 was a rare elemene-type sesquiterpenoid with a furan ring fragment, which is mostly lactone ring in its analogues. The structures of new compounds were determined on the basis of extensive spe...
Kashkooli, Arman Beyraghdar van Dijk, Aalt D.J. Bouwmeester, Harro van der Krol, Alexander
Key message: A highly specialized function for individual LTPs for different products from the same terpenoid biosynthesis pathway is described and the function of an LTP GPI anchor is studied. Abstract: Sequiterpenes produced in glandular trichomes of the medicinal plant Tanacetum parthenium (feverfew) accumulate in the subcuticular extracellular ...
Liu, Tao Chen, Xiangyu Hu, Yuze Li, Menghe Wu, Yanting Dai, Minghui Huang, ZhiLin Sun, Pinghua Zheng, Junxia Ren, Zhe
...
Published in
Phytochemistry
In this study, eight undescribed sesquiterpenoids (artemvulactone A-G and artemvulemdiol A), and two undescribed triterpenoids, (3S)-dammar-20,25-diene-3-hydroxy-24-one and (3S,23E)-dammar-20,23-diene-25- methoxy-3-ol were isolated from the leaves of Artemisia vulgaris L., together with ten known sesquiterpenoids and three known triterpenoids. The ...
Yang, Yong-Cheng Liu, Lu-Qi Wang, Kun-Jun Zhang, Xue-Qing Fan, San-Peng Gao, Xiao-Xu Wang, An-Hua Jia, Jing-Ming Fu, Chun-Wang
Published in
Natural product research
Four sesquiterpenoids A-D (1-4) were isolated from the ethanol extracts of the leaves and stems from Schisandra chinensis. Their structures and absolute configurations were elucidated by a combination of NMR, MS and ECD. Compounds 1-4 (10 μM) exhibited moderate hepatoprotective activities against APAP-induced LO2 cell damage with increasing cell vi...