Molenaar, Nina Maren Lambregtse-van den Berg, Mijke Pietertje... Bonsel, Gouke Jacobus
Published in
Archives of women's mental health
Management of mental illness in the perinatal period with antidepressants is controversial, since evidence emerged on potential harmful effects to the unborn child. However, over time, the dispensing of antidepressants in the perinatal period has increased. We examined perinatal dispensing patterns over time and the role of a recently issued guidel...
Sharma, Pallavi Sharma, Supriya Singh, Damanpreet
Published in
Nutritional neuroscience
Objectives: Apigenin is the most common bioflavonoid known to be biologically active after systemic administration and show multiple pharmacological effects. The present study was designed to explore the role of apigenin in pentylenetetrazole (PTZ) kindling associated cognitive and behavioural impairments in the mouse model. Methods: The animals we...
van Donkelaar, Marjolein M J Hoogman, Martine Shumskaya, Elena Buitelaar, Jan K Bralten, Janita Franke, Barbara
Published in
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology
Investigating phenotypic heterogeneity in aggression and understanding the molecular biological basis of aggression subtypes may lead to new prevention and treatment options. In the current study, we evaluated the taxonomy of aggression and examined specific genetic mechanisms underlying aggression subtypes in healthy males and females. Confirmator...
Dos Santos, Rafael Guimarães Hallak, Jaime Eduardo Cecilio
Published in
Neuroscience and biobehavioral reviews
Serotoninergic hallucinogens include drugs such as lysergic acid diethylamide (LSD), dimethyltryptamine (DMT) and psilocybin. Recent trials with single/few doses of these compounds show that they induce rapid and sustained antidepressive, anxiolytic, and antiaddictive effects. These effects are also observed in religious groups using the DMT-contai...
Curtis, Jacob J Vo, Nguyen T K Seymour, Colin B Mothersill, Carmel E
Published in
Environmental research
Ionizing radiation (IR) is an environmental carcinogen and the biological damages it elicits are mechanistically distinct between high and low doses. Non-targeted effects occurring in nonirradiated cells such as the radiation-induced bystander effect predominate at low doses of IR. However, the role of non-targeted effects in environmental radiatio...
Azevedo, Hatylas Ferreira, Marcos Costa, Renata Watanabe Russo, Valter Russo, Elisa Mascarello, Alessandra Guimarães, Cristiano Ruch Werneck
Published in
Progress in neuro-psychopharmacology & biological psychiatry
Anxiety disorders are serious and common mental diseases, yet there is still a need for the development of more effective anxiolytics with better safety profiles than benzodiazepines and serotonin reuptake inhibitors. The serotonergic and noradrenergic systems have reciprocal interactions and are intricately related to the pathogenesis of anxiety. ...
Dumont, Elodie De Bleye, Charlotte Coic, Laureen Sacre, Pierre-Yves Hubert, Philippe Ziemons, Eric
In bioanalysis, where its use has expanded over the last decades, surface-enhanced Raman scattering (SERS) still encounters a major issue: the protein corona. This corona forms due to the adsorption of serum proteins onto the SERS substrates and stabilises the latter while competing with the analyte of interest for its surface. Consequently, this w...
Cheng, Karen Y Frye, Mark A
Published in
Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology
Insects use vision to choose from a repertoire of flexible behaviors which they perform for survival. Decisions for behavioral plasticity are achieved through the neuromodulation of sensory processes, including motion vision. Here, we briefly review the anatomy of the insect motion vision system. Next, we review the neuromodulatory influences on mo...
Eid, Alaa Khoja, Sawsan AlGhamdi, Shareefa Alsufiani, Hadeil Alzeben, Faten Alhejaili, Nasim Tayeb, Haythum O Tarazi, Frank I
Published in
Metabolic brain disease
This study investigated the effects of vitamin D supplementation on Generalized Anxiety Disorder (GAD) clinical symptoms and neurochemical biomarkers including serotonin, neopterin and kynurenine. Thirty male and female patients diagnosed with GAD and had vitamin D deficiency were recruited from the psychiatric clinic at King Abdulaziz University H...
Hatini, Paul G Commons, Kathryn G
Published in
Brain research
Dravet syndrome (DS) is a genetic form of severe epilepsy often associated with mutation of the SCN1A gene encoding the voltage gated sodium channel Nav1.1. Typically refractive to conventional therapy, serotonin neurotransmission may be an innovative target for treatment. To further understand the role of serotonin in this disorder, in this study ...
