Tse, Jeffrey D. Moore, Robert Meng, Yue Tao, Wensi Smith, Elizabeth R. Xu, Xiang-Xi
Published in
BMC Developmental Biology
BackgroundMammalian early development comprises the proliferation, differentiation, and self-assembly of the embryonic cells. The classic experiment undertaken by Townes and Holtfreter demonstrated the ability of dissociated embryonic cells to sort and self-organize spontaneously into the original tissue patterns. Here, we further explored the prin...
Zhong, Chao Yang, Baichuan Huang, Weini Huang, Huan Zhang, Shasha Yan, Xi Lu, Qiaomei Chen, Zhuling Lin, Zian
Published in
Journal of chromatography. A
Fast and highly efficient digestion of proteins is essential for high-throughput proteomic analysis. Herein, a facile approach was developed for self-assembly preparation of trypsin-immobilized capillary monolithic column and its application as an immobilized enzyme microreactor (IMER) for fast and highly efficient proteolysis was described. The pe...
Wang, Fang Cong, Hailin Xing, Jie Wang, Song Shen, Youqing Yu, Bing
Published in
Talanta
The non-specific adsorption of protein has caused many problems in the application of materials. In this paper, a tri-block copolymer PEO-PNIPAAm-PSPMAP with double effects were obtained via atom transfer radical copolymerization (ATRP). The double-effect copolymer is covalently bonded to the hydrophobic material through a photosensitizer to achiev...
Matson, Robert S
Published in
Methods in molecular biology (Clifton, N.J.)
Multiplex immunoassays are important tools in basic research and diagnostics. The ability to accurately quantify the presence of several antigens within an individual sample all at once has been useful in developing a proteomics view of biology. This in turn has enabled the development of disease-associated immunodiagnostic panels for better progno...
Yin, Mengyuan Wan, Yuqi Li, Shuai Zhao, Xiaoting Zhang, Wenwen Zhang, Yun Wang, Hua
Published in
Journal of hazardous materials
Mesoporous melamine-silver (MA-Ag) nanocomposites doped with carbon nitride quantum dots (CNQDs) were fabricated simply by the controlled supramolecular self-assembly. It was discovered that the resulting nanoflower-like [email protected] nanocomposites could exhibit the peroxidase-like catalysis, which could be specifically enhanced by Hg2+ by forming A...
Araste, Fatemeh Aliabadi, Ali Abnous, Khalil Taghdisi, Seyed Mohammad Ramezani, Mohammad Alibolandi, Mona
Published in
Journal of controlled release : official journal of the Controlled Release Society
The progress in advanced materials using nanoscale components can be conducted by an innovative idea involving combining nanotechnology approaches with supramolecular chemistry. This concept which is called self-assembly, is employed for formation of nanoscale self-assembled architectures with desirable properties. Self-assembly has emerged as a po...
Ferreira, Leonardo M B Dos Santos, Aline M Boni, Fernanda Isadora Dos Santos, Karen C Robusti, Leda M Gorla de Souza, Maurício P C Ferreira, Natália N Carvalho, Suzana G Cardoso, Valéria M O Chorilli, Marlus
...
Published in
Carbohydrate polymers
Chitosan-based particles are widely proposed as biocompatible drug delivery systems with mucoadhesive and permeation enhancing properties. However, strategies on how to modulate the intended biological responses are still scarce. Considering that particle properties affect the biological outcome, the rational design of the synthesis variables shoul...
Laroui, Nabila Coste, Maëva Su, Dandan Ali, Lamiaa Bessin, Yannick Barboiu, Mihail Gary-Bobo, Magali Bettache, Nadir Ulrich, Sebastien
Published in
Angewandte Chemie (International ed. in English)
Dynamic covalent libraries enable exploring complex chemical systems from which bioactive assemblies can adaptively emerge through template effects. In this work, we studied dynamic covalent libraries made of complementary bifunctional cationic peptides, yielding a diversity of species from macrocycles to polymers. Although polymers are typically e...
Dolid, Alona Gomes, Luciana C Mergulhão, Filipe J Reches, Meital
Published in
Colloids and surfaces. B, Biointerfaces
This paper describes the fabrication of antifouling surfaces by the combination of topography and peptide chemistry. The topography of the surface mimics the skin of the shark that can resist biofouling by having a certain microtopography. A peptide-based coating that resists fouling self-assembles on these surfaces. In biofilm formation assays, pe...
Li, Weiya Liu, Bin Hubert, Céline Perro, Adeline Duguet, Etienne Ravaine, Serge
We report the formation of colloidal polymers consisting of disk-like silica nanoparticles (NPs) with polystyrene (PS) chains at the bottom of their two cavities assembled through reduction of the solvent quality for the PS chains and linked by hydrophobic associations. We show that this NPs assembly exhibits a two-stage process involving reaction-...
