Published in Journal of Polymer Research
New poly(ester ether)urethanes containing biocide chloramphenicol in the hard segments are presented. SEM microphotographs evidence highly porous morphologies which depend on the nature of polyether segments. The self-assembly ability in micellar aggregates was evidenced by TEM and DLS analyses. Critical micelle concentration values determined by s...
Published in Journal of Nanobiotechnology
BackgroundMany studies have found that ruthenium complexes possess unique biochemical characteristics and inhibit tumor growth or metastasis.ResultsHere, we report the novel dual-targeting ruthenium candidate 2b, which has both antitumor and antimetastatic properties and targets tumor sites through the enhanced permeability and retention (EPR) effe...
Published in Journal of Polymer Research
Effects of poly(ethylene glycol) (PEG) block length on the self-assembly of a series of pH-sensitive poly(N,N-diethylaminoethyl methacrylate)m-PEGn-poly(N,N-diethylaminoethyl methacrylate)m triblock copolymers (PDEAEMAm-PEGn-PDEAEMAm) have been studied. The synthesized triblock copolymers have an almost fixed PDEAEMA block length (m ≈ 65) and varyi...
Published in Journal of Leather Science and Engineering
AbstractPeptide self-assembles with bionic properties have been widely utilized for bioactive drugs and biomedical materials. Collagen mimetic peptide (CMP) gains more attention due to its unique advantages in biosecurity and function. Unfortunately, the self-assembly mechanism of CMP, particularly the effect of intermolecular forces on its self-as...
Amphiphilic peptides that induce catalysis are interesting alternatives to natural enzymes thanks to robustness of their synthesis and the ability to induce certain types of conformations by specific motifs of amino acid sequences. Various studies aimed at mimicking the activity of serine proteases by designed peptides. Here we demonstrate that the...
Published in PhotoniX
AbstractOptical waveguide of organic micro/nanocrystals is one of crucial elements in miniaturized integrated photonics. One-dimensional (1D) organic crystals with various optical features have attracted increasing interests towards promising photonic devices, such as multichannel signal converter, organic field-effect optical waveguide, sensitive ...
Published in Biology Open
Summary: Deuterosome protein 1 (Deup1) self-assembles into stable condensates that can be the structural core of the deuterosome during multiciliogenesis.
Published in eLife
The genetic code stored within DNA contains the instructions for manufacturing all the proteins organisms need to develop, grow and survive. This requires molecular machines that ‘transcribe’ regions of the genetic code into RNA molecules which are then ‘translated’ into the string of amino acids that form the final protein. However, these molecula...
Structure-forming systems are ubiquitous in nature, ranging from atoms building molecules to self-assembly of colloidal amphibolic particles. The understanding of the underlying thermodynamics of such systems remains an important problem. Here we derive the entropy for structure-forming systems that differs from Boltzmann-Gibbs entropy by a term th...
Published in Journal of Nanoparticle Research
Metabolites are essential for the normal operation of cells and fulfill various physiological functions. It was recently found that in several metabolic disorders, the associated metabolites could self-assemble to generate amyloid-like structures, similar to canonical protein amyloids that have a role in neurodegenerative disorders. Yet, assemblies...
