The conventional perception asserts that immunology is the science of ‘discrimination’ between Self and Non-Self. This concept is however no longer tenable as effector cells of the adaptive immune system are first conditioned to be tolerant to the body’s own antigens, collectively known as Self until now. Only then attain these effectors the respon...
Cet ouvrage propose aux étudiants des premières années d’études supérieures une méthode progressive et conviviale pour comprendre et appliquer les concepts fondamentaux de la biologie cellulaire. À la suite de rappels de cours, sous forme de fiches, chaque chapitre propose des exercices de difficulté croissante pour s’évaluer : QCM, questions Vrai/...
The few works on audition in sharks and rays concern only adult specimens. We report the hearing abilities in the dogfish Scyliorhinus canicula at different stages, from embryos that still have their yolk sac inside their egg, to juveniles. Hearing development corresponds to an increase in the frequency range from 100−300 Hz in early pre-hatching s...
Palaeopathology is the study of ancient pathologies preserved in the fossil record. While fossil pathologies have caught interests over the last decades, only those featuring externally-visible manifestations have been extensively studied. A study initially aimed at analysing growth dynamics of two basal sauropods (cf. Isanosaurus and Spinophorosau...
Florin, AntoineLambert, CécileSanchez, ChristelleZappia, JérémieDurieux, NancyTieppo, Antonio MartinsMobasheri, AliHenrotin, Yves
Background Proteomic studies of the secretome of skeletal muscle cells can help us understand the processes that govern the synthesis, systemic interactions and organization of skeletal muscle and identify proteins that are involved in muscular adaptations to exercise, ageing and degeneration. In this systematic review, we aimed to summarize recent...
The absence of preserved soft tissues in the fossil record is frequently a hindrance for palaeontologists wishing to investigate morphological shifts in key skeletal systems, such as the limbs. Understanding the soft tissue composition of modern species can aid in understanding changes in musculoskeletal features through evolution, including those ...
Le virus SARS-CoV-2 provoque un syndrome de détresse respiratoire aiguë, le symptôme principal de l’infection COVID-19 (pour «COronaVIrus Disease 2019»). Cette maladie infectieuse provoque une pandémie de gravité sanitaire et socio-économique majeure depuis décembre 2019. La cible principale du SARS-CoV-2 serait l’alvéole pulmonaire. Néanmoins, ce ...