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with Sciatic nerve lesion as keyword
Dubový, Petr Hradilová-Svíženská, Ivana Klusáková, Ilona Brázda, Václav Joukal, Marek
Published in
Histochemistry and cell biology
To assess the potential role of IL-6 in sciatic nerve injury-induced activation of a pro-regenerative state in remote dorsal root ganglia (DRG) neurons, we compared protein levels of SCG-10 and activated STAT3, as well as axon regeneration in IL-6 knockout (IL-6ko) mice and their wild-type (WT) counterparts. Unilateral sciatic nerve compression and...
Wang, Xiaolong Krebbers, Julia Charalambous, Petar Machado, Venissa Schober, Andreas Bosse, Frank Müller, Hans-Werner Unsicker, Klaus
Published in
Cell and Tissue Research
Growth/differentiation factor-15 (GDF-15) is a distant member of the transforming growth factor beta (TGF-β) superfamily. It is widely distributed in the nervous system, where it has been shown to play an important role in neuronal maintenance. The present study investigates the role of endogenous GDF-15 in sciatic nerve (SN) lesions using wild-typ...
Shim, Ho Yong Lim, Oh Kyung Bae, Keun Hwan Park, Seok Min Lee, Ju Kang Park, Ki Deok
Published in
Annals of rehabilitation medicine
Sciatic nerve injury after stretching exercise is uncommon. We report a case of an 18-year-old female trained dancer who developed sciatic neuropathy primarily involving the tibial division after routine stretching exercise. The patient presented with dysesthesia and weakness of the right foot during dorsiflexion and plantarflexion. The mechanism o...
Dallo, João Gabriel Martins Reichert, Bernardo Vergara Valladão Júnior, José Benedito Ramos Silva, Camila Luca, Bianca Aparecida de Levy, Beatriz de Freitas Azevedo Chadi, Gerson
PURPOSE: Reactive astrocytes are implicated in several mechanisms after central or peripheral nervous system lesion, including neuroprotection, neuronal sprouting, neurotransmission and neuropathic pain. Schwann cells (SC), a peripheral glia, also react after nerve lesion favoring wound/repair, fiber outgrowth and neuronal regeneration. We investig...
