Mallet, Romain Modzelewski, Romain Lequesne, Justine Mihailescu, Sorina Decazes, Pierre Auvray, Hugues Benyoucef, Ahmed Di Fiore, Fréderic Vera, Pierre Dubray, Bernard
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Published in
Radiation Oncology
BackgroundSarcopenia is defined by a loss of skeletal muscle mass with or without loss of fat mass. Sarcopenia has been associated to reduced tolerance to treatment and worse prognosis in cancer patients, including patients undergoing surgery for limited oesophageal cancer. Concomitant chemo-radiotherapy is the standard treatment for locally-advanc...
Chen, Yen-Chih Chen, Pei-Yun Wang, Yu-Chen Wang, Tyng-Guey Han, Der-Sheng
Published in
BMC Geriatrics
Background Sarcopenia and dysphagia are prevalent health issues as the elderly population continues to grow. However, whether sarcopenia, defined by either reduced handgrip strength or gait speed, would lead to pathological effects on swallowing function is still a matter of debate. Studies focusing on subclinical changes in the swallowing function...
Jang, Il-Young Lee, Seungjoo Kim, Jeoung Hee Lee, Eunju Lee, Jin Young Park, So Jeong Kim, Da Ae Hamrick, Mark W. Park, Jin Hoon Kim, Beom-Jun
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Published in
BMC Geriatrics
Background Apelin, an active endogenous peptide, has been recently receiving great attention as a promising target for antiaging intervention, primarily based on results from genetically altered mice. To validate previous experimental data and investigate the possible role of apelin in humans, in this study, we examined serum apelin level in relati...
Li, Xueting Xu, Fengqiang Hu, Longgang Fang, Hao An, Yi
Published in
BMC Geriatrics
Background Sarcopenia is an age-related clinical syndrome characterized by loss of muscle mass and reduced muscle function. Diseases that contribute to sarcopenia include type 2 diabetes mellitus (T2DM), chronic obstructive pulmonary disease (COPD), heart failure, chronic kidney disease, and cancer and others. Fung FY et al. (BMC Geriatrics. 2019;1...
Wang, Jia-bin Xue, Zhen Lu, Jun He, Qing-liang Zheng, Zhi-fang Xu, Bin-bin Xie, Jian-wei Li, Ping Xu, Yu Lin, Jian-xian
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Published in
BMC Cancer
BackgroundThe relationship between sarcopenia and the prognoses of patients with gastric neuroendocrine neoplasms (g-NENs) is unclear. This study was designed to explore the effects of sarcopenia on short-term and long-term outcomes of patients with g-NENs after radical gastrectomy.MethodsThis study retrospectively collected data from 138 patients ...
Xu, Xiao Yang, Zhikai Ma, Tiantian Li, Ziqian Chen, Yuan Zheng, Yingdong Dong, Jie
Published in
Nutrition & Metabolism
BackgroundSarcopenia is common and contributes to a high risk of mortality among general population. There is no consensus regarding the cut-off values for sarcopenia in terms of mortality among chronic kidney disease patients. This study aimed to explore and validate cut-off points of handgrip strength (HGS) and lean mass index (LMI) for estimatin...
Moreno-Gonzalez, Rafael Corbella, Xavier Mattace-Raso, Francesco Tap, Lisanne Sieber, Cornel Freiberger, Ellen Kostka, Tomasz Guligowska, Agnieszka Melzer, Itshak Melzer, Yehudit
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Published in
BMC Geriatrics
BackgroundLoss of muscle mass and function may be more pronounced in older adults with chronic kidney disease (CKD) and with albuminuria. Thus, we investigated the prevalence of sarcopenia among community-dwelling older adults according to kidney function and grade of albuminuria. We also explored differences in the prevalence of sarcopenia accordi...
Hu, Xu Liao, Du-Wu Yang, Zhi-Qiang Yang, Wei-Xiao Xiong, San-Chao Li, Xiang
ABSTRACT Sarcopenia, a concept reflecting the loss of skeletal muscle mass, was reported to be associated with the prognosis of several tumors. However, the prognostic value of sarcopenia in patients with renal cancer remains unclear. We carried out this metaanalysis and systematic review to evaluate the prognostic value of sarcopenia in patients w...
Erős, Adrienn Soós, Alexandra Hegyi, Péter Szakács, Zsolt Benke, Márton Szűcs, Ákos Hartmann, Petra Erőss, Bálint Sarlós, Patricia
Published in
Surgery Today
Patients with inflammatory bowel disease (IBD) are at risk of sarcopenia, which is associated with poor clinical outcomes. We conducted this study to assess whether sarcopenia predicts the need for surgery and postoperative complications in patients with IBD. We performed a systematic search of four electronic databases, last updated in March, 2019...
Sugawara, Kotaro Yamashita, Hiroharu Urabe, Masayuki Okumura, Yasuhiro Yagi, Koichi Aikou, Susumu Seto, Yasuyuki
Published in
European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
The survival impacts of the prognostic nutritional index (PNI) and sarcopenia have been separately investigated in patients with gastric carcinoma (GC), while the prognostic impact of the combination of them remains to be addressed. In total, 1166 GC patients undergoing radical gastrectomy were retrospectively reviewed. A new prognostic score (PNIS...
