Kaur, Avinash Ruhela, Ankur Sharma, Priyanka Khariwal, Harshit Seth, Sagar Kumar, Adarsh Kapil, Arti Elangovan, Ravikrishnan Kalyanasundaram, Dinesh
Published in
Biomedical Microdevices
Enteric fever is one of the leading causes of infection and subsequent fatality (greater than 1.8 million) (WHO 2018), especially in the developing countries due to contaminated water and food inter twinned with unhygienic practices. Clinical gold standard technique of culture-based method followed by biochemical tests demand 72+ hours for diagnosi...
Oli, Angus Nnamdi Obaji, Monday Enweani, Ifeoma Bessie
Published in
BMC Research Notes
ObjectivesThis study examines the rationale, if any, behind combining the extracts from the fruits of Alchornea cordifolia and Pterocarpus santalinoides and aerial parts of Cassytha filiformis in the traditional treatment of diarrhoegenic bacterial infections.ResultsFour diarrhoegenic bacterial isolates: Salmonella typhi, Shigellae dysenteriae, Esc...
López-Segura, Nuria Corberó-Rivali, Carla Maldonado-Fernández, Maria Cristina Calpe-Fraile, Sara Peyra-Ros, Jorge Martínez-Roig, Antoni
Published in
Journal of travel medicine
Jindal, Ankur Kumar Suri, Deepti Guleria, Sandesh Rawat, Amit Garg, Sumit Bal, Amanjit Casanova, Jean-Laurent Bustamante, Jacinta Singh, Surjit
Published in
Journal of Clinical Immunology
Harrison, Jerry Joe E.K. Ayine-Tora, Moscoh Daniel Appiagyei, Benjamin Mills-Robertson, Felix C. Asomaning, William A. Achel, Daniel G. Ishida, Hiroyuki Kingsford-Adaboh, Robert
Published in
Zeitschrift für Kristallographie - Crystalline Materials
We report a systematic study of the antibacterial inhibitory potential of isoflavone natural products isolated from the seeds extracts of Millettia thonningii. In an effort to gain bond topological information which may have consequences for the observed bioactivities, the crystal structure of robustic acid was solved and refined using the independ...
Samykannu, Gopinath Vijayababu, Princy Antonyraj, Christian Bharathi Perumal, Perumal Narayanan, Sundarabaalaji Basheer Ahamed, Syed Ibrahim Natarajan, Jeyakumar
Published in
Journal of computational biology : a journal of computational molecular cell biology
Typhoid fever is an acute illness in humans, caused by Salmonella typhi, a gram-negative bacterium. Outer membrane proteins of S. typhi have strong potential for its use in the development of subunit vaccine against typhoid. In the current study, peptide-based subunit vaccine was constructed from outer membrane protease E (PgtE) against S. typhi. B...
Subramaniam, Sivaraman Müller, Volker S Hering, Nina A Mollenkopf, Hans Becker, Daniel Heroven, Ann Kathrin Dersch, Petra Pohlmann, Anne Tedin, Karsten Porwollik, Steffen
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The Cpx-envelope stress system regulates the expression of virulence factors in many Gram-negative pathogens. In Salmonella enterica serovar Typhimurium deletion of the sensor kinase CpxA but not of the response regulator CpxR results in the down regulation of the key regulator for invasion, HilA encoded by the Salmonella pathogenicity island 1 (SP...
Park, Se Eun Pham, Duy Thanh Boinett, Christine Wong, Vanessa K Pak, Gi Deok Panzner, Ursula Espinoza, Ligia Maria Cruz von Kalckreuth, Vera Im, Justin Schütt-Gerowitt, Heidi
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Kingsley, Robert A Langridge, Gemma Smith, Sarah E Makendi, Carine Fookes, Maria Wileman, Thomas El Ghany, Moataz Abd Keith Turner, A Dyson, Zoe A Sridhar, Sushmita
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Mutter, Natalie L Soskine, Misha Huang, Gang Albuquerque, Inês S Lopes Bernardes, Goncalo Maglia, Giovanni
Immunotoxins are proteins containing a cell-targeting element linked to a toxin that are under investigation for next-generation cancer treatment. These agents, however, are difficult to synthesize, chemically heterogeneous, expensive and show toxicity towards healthy cells. In this work, we describe the synthesis and characterization of a new kind...
