Yang, Tong Ng, Derry Minyao Du, Nannan He, Ning Dai, Xiaoyu Chen, Ping Wu, Feng Chen, Bo Fan, Xiaoxiang Yan, Kun
...
Published in
Surgical endoscopy
The goal of this study is to evaluate the safety and efficacy of high intensity focused ultrasound (HIFU) for patients with colorectal liver metastases (CRLM) but were contraindicated for resection and radiofrequency ablation. Patients between 20 and 80 years of age with 1-3 liver metastases from colorectal cancer were selected. Included patients h...
Levy, Sharon Tennermann, Nicole Marin, Alexandra C Wiseblatt, Aria Shrier, Lydia A Garvey, Katharine Dedeoglu, Fatma Fishman, Laurie N Weitzman, Elissa R
Published in
The Journal of adolescent health : official publication of the Society for Adolescent Medicine
Research involving adolescent risk behaviors must balance data confidentiality with participant safety when risky behaviors are revealed. This report details a safety protocol and reports the experience of two contemporaneous studies that used it with variant safety thresholds. We developed a safety protocol for research with adolescent patients an...
Chng, Bee Ling Kelly Hon, Jin Shing Chan, Hong Zheng, Yiliang Gao, Fei Teo, Loon Yee Louis Sim, Kheng Leng David
Published in
Heart, lung & circulation
The Comparison of Pre- and Post-discharge Initiation of LCZ696 Therapy in HFrEF Patients After an Acute Decompensation Event (TRANSITION) and PIONEER-HF trialsa have shown that sacubitril/valsartan can be initiated early and safely in patients with heart failure with reduced ejection fraction (HFrEF) shortly after an acute heart failure episode dur...
Bengtsson, Mariette Ekedahl, Ann-Britt Ivarsson Sjöström, Karin
Published in
BMC Nursing
BackgroundThe number of errors in medication management in nursing homes is increasing, which may lead to potentially life-threatening harm. Few studies on this subject are found in the municipal nursing home setting, and causes need to be identified. The aim of this study was to explore perceptions of errors connected to medication management in n...
Martinelli, Massimo Quaglietta, Lucia Banderali, Giuseppe Ferrara, Pietro Romano, Claudio Staiano, Annamaria
Published in
Italian Journal of Pediatrics
BackgroundDespite ibuprofen widely recognized safety profile, an increase of suspected adverse events has been reported in the last decade in parallel with its growing over-the-counter use. The aims of this study were to assess the therapeutic approach to the feverish child and to evaluate the main indications and the most frequent adverse events r...
Bakker, Charlotte Tasker, Tim Liptrot, Jan Hart, Ellen P. Klaassen, Erica S. Doll, Robert Jan Brown, Giles A. Brown, Alastair Congreve, Miles Weir, Malcolm
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Published in
Alzheimer's Research & Therapy
BackgroundThe cholinergic system and M1 receptor remain an important target for symptomatic treatment of cognitive dysfunction. The selective M1 receptor partial agonist HTL0018318 is under development for the symptomatic treatment of Dementia’s including Alzheimer’s disease (AD) and dementia with Lewy bodies (DLB). We investigated the safety, tole...
Xia, Lin-Yu Hu, Qing-Lin Zhou, Qing
Published in
BMC Women's Health
BackgroundTrastuzumab is currently the standard treatment for human epidermal growth factor receptor 2 (HER2)-positive breast cancer. However, it is not recommended for HER2-positive breast cancer patients during pregnancy as it may jeopardize safety of the fetus. Nevertheless, there is evidence that fetuses exposed to trastuzumab in early stages o...
Mihretu, Fassil
Published in
Patient Safety in Surgery
BackgroundImproving patient safety during anesthesia and surgery becomes a major global public health issue due to the increasing in surgical burden. Anesthesia is delivered safely in developed countries, but its safety is hampered by complex problems in third world countries. This survey assesses the unmet anesthesia needs of one of a third world ...
Romano, C
Published in
Journal of investigational allergology & clinical immunology
Serai, Suraj D. Ho, Mai-Lan Artunduaga, Maddy Chan, Sherwin S. Chavhan, Govind B.
Published in
Pediatric Radiology
Magnetic resonance imaging (MRI) is a powerful diagnostic tool that can be optimized to display a wide range of clinical conditions. An MRI system consists of four major components: a main magnet formed by superconducting coils, gradient coils, radiofrequency (RF) coils, and computer systems. Each component has safety considerations. Unless careful...
