AUMENTO DE LA RESILIENCIA DE LAS CARRETERAS MEDIANTE EL USO COMBINADO DE TECNOLOGÍA MULTISENSOR Y MODELOS CLIMÁTICOS
VI Congreso Cuidades Inteligentes, MADRID, ESPAGNE, 15-/09/2020 - 15/09/2020
Perceived utility and feasibility of pathogen genomics for public health practice: a survey among public health professi...
Published in BMC Public Health
BackgroundPathogen genomics is increasingly being translated from the research setting into the activities of public health professionals operating at different levels. This survey aims to appraise the literacy level and gather the opinions of public health experts and allied professionals working in the field of infectious diseases in Belgium conc...
A Practical Method to Implement Strain-Level Metagenomics-Based Foodborne Outbreak Investigation and Source Tracking in ...
Published in Microorganisms
The management of a foodborne outbreak depends on the rapid and accurate identification of the responsible food source. Conventional methods based on isolation of the pathogen from the food matrix and target-specific real-time polymerase chain reactions (qPCRs) are used in routine. In recent years, the use of whole genome sequencing (WGS) of bacter...
The Benefits of Whole Genome Sequencing for Foodborne Outbreak Investigation from the Perspective of a National Referenc...
...Published in Foods (Basel, Switzerland)
Gradually, conventional methods for foodborne pathogen typing are replaced by whole genome sequencing (WGS). Despite studies describing the overall benefits, National Reference Laboratories of smaller countries often show slower uptake of WGS, mainly because of significant investments required to generate and analyze data of a limited amount of sam...
Targeted next-generation sequencing of sputum for diagnosis of drug-resistant TB: results of a national survey in Democr...
The surveillance of drug resistance among tuberculosis (TB) patients is central to preventing the spread of antimicrobial resistance. The Democratic Republic of the Congo (DR Congo) is classified by the World Health Organization (WHO) as a country with a high burden of TB and multidrug-resistant TB (MDR-TB), but there are no nationally representati...
T cells engineered to target senescence
Senescence is a hallmark of cellular ageing and contributes to many diseases. A new method enabling immune cells to target senescent cells might offer improved therapeutic options.
Introducing PIONEER: a project to harness big data in prostate cancer research
...
Prostate Cancer Diagnosis and Treatment Enhancement Through the Power of Big Data in Europe (PIONEER) is a European network of excellence for big data in prostate cancer, consisting of 32 private and public stakeholders from 9 countries across Europe. Launched by the Innovative Medicines Initiative 2 and part of the Big Data for Better Outcomes Pro...
Guidelines for the Li-Fraumeni and heritable TP53-related cancer syndromes
Fifty years after the recognition of the Li-Fraumeni syndrome (LFS), our perception of cancers related to germline alterations of TP53 has drastically changed: (i) germline TP53 alterations are often identified among children with cancers, in particular soft-tissue sarcomas, adrenocortical carcinomas, central nervous system tumours, or among adult ...
Female sex is associated with comparable 5-year outcomes after contemporary endovascular aneurysm repair despite more ch...
Published in Journal of vascular surgery
Women with abdominal aortic aneurysms less often meet anatomic criteria for endovascular repair and experience worse perioperative and long-term survival. We compared long-term survival, aneurysm-related mortality, and rates of endoleaks and reinterventions between male and female patients in the Endurant Stent Graft Natural Selection Global Postma...
Efficacy, immunogenicity, and safety of IC43 recombinant Pseudomonas aeruginosa vaccine in mechanically ventilated inten...
...Published in Critical Care
BackgroundPseudomonas aeruginosa infections are a serious threat in intensive care units (ICUs). The aim of this confirmatory, randomized, multicenter, placebo-controlled, double-blind, phase 2/3 study was to assess the efficacy, immunogenicity, and safety of IC43 recombinant Pseudomonas aeruginosa vaccine in non-surgical ICU patients.MethodsEight ...
