A microemulsion system based on ionic liquid (IL) and deep eutectic compound was proposed to improve the transdermal delivery of artemisinin. Deep eutectic lidocaine ibuprofen (Lid center dot Ibu) was selected as the oil phase, and the imidazolium ionic liquid, 1-hydroxyethyl-3-methylimidazolium chloride ([HOEmim]Cl), was incorporated into the aque...
A microemulsion system based on ionic liquid (IL) and deep eutectic compound was proposed to improve the transdermal delivery of artemisinin. Deep eutectic lidocaine ibuprofen (Lid center dot Ibu) was selected as the oil phase, and the imidazolium ionic liquid, 1-hydroxyethyl-3-methylimidazolium chloride ([HOEmim]Cl), was incorporated into the aque...
pH-sensitive hydrogels have developed greatly over the past few years. This has been possible due to the synthesis of new hydrogel systems with increased sensitivity - the sensitivity of up to 10-5 pH units have already been established. Recently, pH-sensitive hydrogels have shown to be very useful for biomedical applications, such as targeted canc...
Deep tissue injuries are pressure ulcers which initiate in the subcutaneous tissues and extend through a bottom-up pathway. Once deep tissue injuries are visual at skin level, serious irreversible tissue damage has already occurred. In pressure ulcer development, inflammation and edema are coupled physiological processes associated with tissue dama...
Iontronic graphene tactile sensors (i-GTS) composed of a top floating graphene electrode and an ionic liquid droplet pinned on a bottom graphene grid, which can dramatically enhance the performance of capacitive-type tactile sensors, are presented. When mechanical stress is applied to the top floating electrode, the i-GTS operates in one of the fol...
A highly flexible, stretchable, and mechanically robust low‐cost soft composite consisting of silicone polymers and water (or hydrogels) is reported. When combined with conventional acoustic transducers, the materials reported enable high performance real‐time monitoring of heart and respiratory patterns over layers of clothing (or furry skin of an...
status: published
Sourdough starters are naturally occurring microbial communities in which the environment, ingredients, and bakers are potential sources of microorganisms. The relative importance of these pools remains unknown. Here, bakers from two continents used a standardized recipe and ingredients to make starters that were then baked into breads. We characte...
Abundant corneocyte surface protrusions, observed in patients with atopic dermatitis with filaggrin loss-of-function mutations, are inversely associated with levels of natural moisturizing factors (NMFs) in the stratum corneum. To dissect the etiological role of NMFs and filaggrin deficiency in surface texture alterations, we examined mouse models ...
This study proposes the development of a landscape-scale multitemporal soil pattern analysis (MSPA) method for organic matter (OM) estimation using RapidEye time series data analysis and GIS spatial data modeling, which is based on the methodology of Blasch et al. The results demonstrate (i) the potential of MSPA to predict OM for single fields and...
