Nicotine binds to nicotinic acetylcholine receptors (nAChRs) that are overexpressed in different cancer cells, promoting tumor growth and resistance to chemotherapy. In this study, we aimed to investigate the potential of APS7-2 and APS8-2, synthetic analogs of a marine sponge toxin, to inhibit nicotine-mediated effects on A549 human lung cancer ce...
Understanding the spatial scales at which organisms can adapt to strong natural and human-induced environmental gradients is important. Salinization is a key threat to biodiversity, ecosystem functioning and the provision of ecosystem services of freshwater systems. Clusters of naturally saline habitats represent ideal test cases to study the exten...
Vapour explosions are a known hazard with potentially devastating consequences in several industries. They might occur when a hot liquid comes into direct contact with a cold and volatile liquid. Eutectic PbS-Cu2S droplet impingement experiments were performed to investigate the effect of the coolant composition on the vapour explosion behaviour. T...
Published in Skin Appendage Disorders
Introduction: Alopecia areata (AA) is an autoimmune disease characterized by T cell‐mediated attack on the hair follicle. Although there are a wide range of therapies, the majority of them are not satisfactory due to side effects, pain due to intralesional injections or limited efficacy. In this study, we sought to evaluate the efficacy, influence ...
Published in Frontiers in Disaster and Emergency Medicine
Background Triage is an initial important step in emergency medical rescues for mass casualty incidents, and different triage systems are used in practice. However, quantitative analysis-based evidence comparing these triage systems in mass casualty incidents is limited. Objective To compare the performance of three triage systems, simple triage an...
Published in The Journal of investigative dermatology
Although progress has been made in developing outcome measures for AA, the use of these measures remains unstandardized. A scoping review was conducted to identify the clinician-reported outcome measures (ClinROMs) and patient-reported outcome measures (PROMs) used in assessing and treating AA, the results of which revealed heterogeneity in AA outc...
As a facile method to facilitate the uniform lithium deposition on the lithium metal anode, a unique solid electrolyte complexion consisted of polyethylene oxide, UiO-66-NH2, and deep eutectic solvents (PEMD) with nanoconfinement significantly improves the lithium metal cycling stability. Specifically, the free amide molecules of deep eutectic solv...
Phospholipase C (PLC) has been implicated in several stress responses, including drought. Overexpression (OE) of PLC has been shown to improve drought tolerance in various plant species. Arabidopsis contains nine PLC genes, which are subdivided into four clades. Earlier, OE of PLC3, PLC5 or PLC7 was found to increase Arabidopsis' drought tolerance....
As a facile method to facilitate the uniform lithium deposition on the lithium metal anode, a unique solid electrolyte complexion consisted of polyethylene oxide, UiO-66-NH2, and deep eutectic solvents (PEMD) with nanoconfinement significantly improves the lithium metal cycling stability. Specifically, the free amide molecules of deep eutectic solv...
Simple Summary The study examined whether dietary supplements such as citrate or NaCl have an influence on the development of urinary calcium oxalate crystals in fattening pigs. There were three examination groups: a control group, a citrate group and a NaCl group. Parameters of comparison were performance (average daily gain and feed intake, feed ...
