Ciappuccini, Renaud Heutte, Natacha Lasne-Cardon, Audrey Saguet-Rysanek, Virginie Leroy, Camille Le Hénaff, Véronique Vaur, Dominique Babin, Emmanuel Bardet, Stéphane
Published in
BMC Cancer
BackgroundIn patients with differentiated thyroid cancer (DTC), tumor burden of persistent disease (PD) is a variable that could affect therapy efficiency. Our aim was to assess its correlation with the 2015 American Thyroid Association (ATA) risk-stratification system, and its impact on response to initial therapy and outcome.MethodsThis retrospec...
Cristoferi, Laura Nardi, Alessandra Invernizzi, Pietro Mells, George Carbone, Marco
Published in
Surgical oncology clinics of North America
The evolving research landscape, with advances in the omics technologies, availability of large-scale patient cohorts, and forthcoming availability of novel drugs in primary biliary cholangitis (PBC), is creating a unique opportunity for developing a precision medicine (PM) program. PM has potential to change the paradigm of management. Diagnostic ...
Sannino, Giuseppina Marchetto, Aruna Ranft, Andreas Jabar, Susanne Zacherl, Constanze Alba-Rubio, Rebeca Stein, Stefanie Wehweck, Fabienne S Kiran, Merve M Hölting, Tilman L B
...
Published in
EBioMedicine
Up to 30-40% of Ewing sarcoma (EwS) patients with non-metastatic disease develop local or metastatic relapse within a time span of 2-10 years. This is in part caused by the absence of prognostic biomarkers that can identify high-risk patients and thus assign them to risk-adapted monitoring and treatment regimens. Since cancer stemness has been asso...
Khanlari, Sarah Barnett AM, Bryanne Ogbo, Felix Akpojene Eastwood, John
Published in
BMC Pregnancy and Childbirth
BackgroundGlobally, anxiety and depression are the most common complications of the perinatal period (conception to 1 year postpartum). It is now recognised that anxiety and depression are more commonly found antenatally than postnatally and represent the greatest risk factor for developing postnatal depression. Research in this space has focused o...
Moroney, Marisa R Davies, Kurtis D Wilberger, Adam C Sheeder, Jeanelle Post, Miriam D Berning, Amber A Fisher, Christine Lefkowits, Carolyn Guntupalli, Saketh R Behbakht, Kian
...
Published in
Gynecologic oncology
Stage I, grade 1 endometrial cancers have low recurrence rates and often do not receive adjuvant therapy. We compared recurrent cases to matched non-recurrent controls to evaluate for molecular markers associated with higher risk of recurrence. A case-control study including all cases of recurrent stage I, grade 1 endometrioid endometrial cancer at...
González-Pacheco, Héctor Bojalil, Rafael Amezcua-Guerra, Luis M Sandoval, Julio Eid-Lidt, Guering Arias-Mendoza, Alexandra Azar-Manzur, Francisco Álvarez-Sangabriel, Amada Altamirano-Castillo, Alfredo Briseño-Cruz, José L
...
Published in
Journal of cardiology
Accurate assessment of inflammatory status of patients during acute coronary syndrome (ACS) has become of great importance in their risk classification and in the research of new anti-inflammatory therapies. The study cohort included 7396 patients with ACS. We sought to derive and internally validate an inflammation-based score that included high-s...
Zhu, Rui Yang, Xin Guo, Wenna Xu, Xin-Jian Zhu, Liucun
Published in
PeerJ
Bladder cancer is one of the most common cancers, and its histopathological type is mainly bladder urothelial carcinoma, accounting for about 90%. The prognostic biomarkers of bladder cancer are classified into clinical features biomarkers and molecular biomarkers. Nevertheless, due to the existence of individual specificity, patients with similar ...
Kanwar, Manreet K Lohmueller, Lisa C Kormos, Robert L Teuteberg, Jeffrey J Rogers, Joseph G Lindenfeld, JoAnn Bailey, Stephen H McIlvennan, Colleen K Benza, Raymond Murali, Srinivas
...
Published in
JACC. Heart failure
This study investigates the use of a Bayesian statistical models to predict survival at various time points in patients undergoing left ventricular assist device (LVAD) implantation. LVADs are being increasingly used in patients with end-stage heart failure. Appropriate patient selection continues to be key in optimizing post-LVAD outcomes. Data us...
Pang, Peter S Collins, Sean P Gheorghiade, Mihai Butler, Javed
Published in
Cardiology clinics
The majority of patients hospitalized with acute heart failure (AHF) initially present to the emergency department (ED). Correct diagnosis followed by prompt treatment ensures optimal outcomes. Paradoxically, identification of high risk is not the unmet need, given nearly all ED AHF patients are hospitalized; rather, it is identification of low-ris...
Voscopoulos, Christopher Theos, Kimberly Tillmann Hein, H. A. George, Edward
Published in
Journal of Clinical Monitoring and Computing
Late detection of respiratory depression in non-intubated patients compromises patient safety. SpO2 is a lagging indicator of respiratory depression and EtCO2 has proven to be unreliable in non-intubated patients. A decline in minute ventilation (MV) is the earliest sign of respiratory depression. A non-invasive respiratory volume monitor (RVM) tha...
