Association between the Average Ratio of Platelet Volume and the Presence of Mural Thrombus in Post-Myocardial Infarctio...
Transcatheter Aortic Valve Implantation: Where are we in 2020?
Abstract Aortic stenosis is an insidious disease of rapid progression after the onset of symptoms. Aortic valve replacement surgery is a well-established therapy that reduces symptoms and increases survival rates. However, the procedure may be associated with high operative mortality rates and promote comorbidity. Depending on the local reality, th...
Inflammation in Cardiovascular Disease: From Basic Concepts to Clinical Application
Abstract Although low-density lipoprotein cholesterol is central to the development and progression of atherosclerosis, the role of inflammation in the atherosclerotic process is becoming better understood and appreciated. Chronic inflammatory conditions such as rheumatoid arthritis, lupus, psoriasis, HIV infection, and inflammatory bowel disease h...
Intestinal Microbiota and Cardiovascular Diseases
Abstract Recently, gut microbiota has emerged as an important mediator of several diseases such as diabetes, atherosclerosis, arterial hypertension, obesity, cancers and neuropsychiatric diseases including Alzheimer, autism and depression. Intestinal microbiota is formed by bacteria, fungi and viruses and its main function is to facilitate the abso...
The shape of the global causes of death
BACKGROUND: World maps can provide an instant visual overview of the distribution of diseases and deaths. RESULTS: There is a particular geography to each type of death: in some places many thousands of deaths are caused by a particular condition, whilst other equally populous areas have few to no deaths from the same cause. CONCLUSION: Physicians ...
Pan-cancer study detects genetic risk variants and shared genetic basis in two large cohorts.
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Deciphering the shared genetic basis of distinct cancers has the potential to elucidate carcinogenic mechanisms and inform broadly applicable risk assessment efforts. Here, we undertake genome-wide association studies (GWAS) and comprehensive evaluations of heritability and pleiotropy across 18 cancer types in two large, population-based cohorts: t...
Relation Between Neck Pain and Modic Changes in Cervical Spondylotic Myelopathy
Published in Medical Science Monitor : International Medical Journal of Experimental and Clinical Research
Background Modic changes on magnetic resonance imaging (MRI) represent lesions in the bone marrow of the vertebral body that may be associated with pain. This study investigated the relationship between neck pain and cervical Modic changes, and risk factors for neck pain (NP). Material/Methods This study included 168 patients diagnosed with cervica...
Older Adults With Coronavirus Disease 2019; A Nationwide Study in Turkey
...Published in The Journals of Gerontology Series A: Biological Sciences and Medical Sciences
Background A novel coronavirus (severe acute respiratory syndrome coronavirus 2 [SARS-CoV-2]) occurred in China in December 2019 and has spread globally. In this study we aimed to describe the clinical characteristics and outcomes of hospitalized older adults with coronavirus disease 2019 (COVID-19) in Turkey. Methods We retrospectively analyzed th...
Is Increased Sleep Responsible for Reductions in Myocardial Infarction During the COVID-19 Pandemic?
The COVID-19 pandemic caused by the highly contagious SARS-CoV-2 virus has had devastating consequences across the globe. However, multiple clinics and hospitals have experienced a decrease in rates of acute myocardial infarction and corresponding cardiac catheterization lab activations, raising the question: Has the risk of myocardial infarction d...
Call to Action: SARS-CoV-2 and CerebrovAscular DisordErs (CASCADE).
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BACKGROUND AND PURPOSE:The novel severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2), now named coronavirus disease 2019 (COVID-19), may change the risk of stroke through an enhanced systemic inflammatory response, hypercoagulable state, and endothelial damage in the cerebrovascular system. Moreover, due to the current pandemic, some count...
