Cebere, Bogdan Pashayan, Nora Navani, Neal van der Schaar, Mihaela Janes, Sam Callender, Thomas Imrie, Fergus
BACKGROUND: Risk-based screening for lung cancer is currently being considered in several countries; however, the optimal approach to determine eligibility remains unclear. Ensemble machine learning could support the development of highly parsimonious prediction models that maintain the performance of more complex models while maximising simplicity...
Taylor, Lily C Dennison, Rebecca A Griffin, Simon J John, Stephen D Lansdorp-Vogelaar, Iris Thomas, Chloe V Thomas, Rae Usher-Smith, Juliet A
BackgroundPopulation-based cancer screening programmes are shifting away from age and/or sex-based screening criteria towards a risk-stratified approach. Any such changes must be acceptable to the public and communicated effectively. We aimed to explore the social and ethical considerations of implementing risk stratification at three different sta...
Greenhow, Tara Nguyen, Tran Young, Beverly Somers, Madeline Huang, Jie Alabaster, Amy Vinson, David Mark, Dustin Van Winkle, Patrick Sharp, Adam
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Introduction There is considerable variation in the approach to infants presenting to the emergency department (ED) with fever. The authors primary aim was to develop a robust set of algorithms using community ED data to inform modifications of broader clinical guidance. Methods The authors report the development of California Febrile Infant Risk S...
Taylor, Lily C Dennison, Rebecca A Griffin, Simon J John, Stephen D Lansdorp-Vogelaar, Iris Thomas, Chloe V Thomas, Rae Usher-Smith, Juliet A
BACKGROUND: Population-based cancer screening programmes are shifting away from age and/or sex-based screening criteria towards a risk-stratified approach. Any such changes must be acceptable to the public and communicated effectively. We aimed to explore the social and ethical considerations of implementing risk stratification at three different s...
Dakour-Aridi, Hanaa Vyas, Punit K Schermerhorn, Marc Malas, Mahmoud Eldrup-Jorgensen, Jens Cronenwett, Jack Wang, Grace Kashyap, Vikram S Motaganahalli, Raghu L
ObjectiveSignificant regional variation is known with multiple surgical procedures. This study describes regional variation in carotid revascularization within the Vascular Quality Initiative (VQI).MethodsData from the VQI carotid endarterectomy (CEA) and carotid artery stenting (CAS) databases from 2016 to 2021 were used. Nineteen geographic VQI r...
Zarrintan, Sina Malas, Mahmoud B
Carotid endarterectomy (CEA) is the gold-standard method of carotid revascularization in symptomatic patients with ≥50% and in asymptomatic patients with ≥70% stenosis. Transfemoral carotid artery stenting (TFCAS) has been associated with higher perioperative stroke rates compared to CEA in several studies. On the other hand, transcarotid artery re...
Zaorsky, Nicholas Proudfoot, James Jia, Angela Zuhour, Raed Vince, Randy Liu, Yang Zhao, Xin Hu, Jim Schussler, Nicola Stevens, Jennifer
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BACKGROUND: Management of localized or recurrent prostate cancer since the 1990s has been based on risk stratification using clinicopathological variables, including Gleason score, T stage (based on digital rectal exam), and prostate-specific antigen (PSA). In this study a novel prognostic test, the Decipher Prostate Genomic Classifier (GC), was us...
Bert, Fabrizio Cugudda, Eleonora Lo Moro, Giuseppina Devardo, Carolina Citino, Elena Faenzi, Cristina Scarmozzino, Antonio Siliquini, Roberta
Published in
Journal of public health (Oxford, England)
Untimely social interventions prolong hospitalizations, suggesting discharge planning should begin early. This study aimed to create a tool to identify, already in Emergency department, patients at risk of complex discharge for social reasons. We developed the Risk Assessment of Complex Discharge Index (RACDI). In Emergency department, we administe...
Testa, Alexander Jacobs, Benjamin Zhang, Lixia Jackson, Dylan Ganson, Kyle Nagata, Jason
OBJECTIVES: This study assesses the association between adverse childhood experiences (ACEs) and prescription opioid use during pregnancy. METHODS: This study uses data on 2,999 individuals from the 2019 and 2020 Pregnancy Risk Assessment Monitoring System (PRAMS) from North Dakota and South Dakota. The relationship between ACEs and prescription op...
Hageman, Steven HJ Petitjaen, Carmen Pennells, Lisa Kaptoge, Stephen Pajouheshnia, Romin Tillmann, Taavi Blaha, Michael J McClelland, Robyn L Matsushita, Kunihiro Nambi, Vijay
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AIMS: In clinical practice, factors associated with cardiovascular disease (CVD) like albuminuria, education level, or coronary artery calcium (CAC) are often known, but not incorporated in cardiovascular risk prediction models. The aims of the current study were to evaluate a methodology for the flexible addition of risk modifying characteristics ...