An interlaboratory comparison of mid-infrared spectra acquisition: Instruments and procedures matter
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status: published
Visual comet scoring revisited: a guide to scoring comet assay slides and obtaining reliable results.
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Published in Mutagenesis
Measurement of DNA migration in the comet assay can be done by image analysis or visual scoring. The latter accounts for 20%-25% of the published comet assay results. Here we assess the intra- and inter-investigator variability in visual scoring of comets. We include three training sets of comet images, which can be used as reference for researcher...
An interlaboratory comparison of mid-infrared spectra acquisition : instruments and procedures matter
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Diffuse reflectance spectroscopy has been extensively employed to deliver timely and cost-effective predictions of a number of soil properties. However, although several soil spectral laboratories have been established worldwide, the distinct characteristics of instruments and operations still hamper further integration and interoperability across ...
An interlaboratory comparison of mid-infrared spectra acquisition : Instruments and procedures matter
...
Diffuse reflectance spectroscopy has been extensively employed to deliver timely and cost-effective predictions of a number of soil properties. However, although several soil spectral laboratories have been established worldwide, the distinct characteristics of instruments and operations still hamper further integration and interoperability across ...
An OECD TG 428 study ring trial with 14C-Caffeine demonstrating repeatability and robustness of the dermal absorption in...
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Published in Regulatory toxicology and pharmacology : RTP
The dermal absorption potential of 14C-Caffeine applied as a 4 mg/mL concentration (10 μL/cm2 finite dose) was investigated in six laboratories under Good Laboratory Practice conditions using an OECD TG 428-compliant in vitro assay with flow-through cells and split-thickness human skin. Potential sources of variation were reduced by a standardized ...
Immunohistochemistry as a screening tool for NTRK gene fusions: results of a first Belgian ring trial.
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Published in Virchows Archiv : an international journal of pathology
A Belgian ring trial for pan-TRK immunohistochemistry (IHC) staining was organised to harmonise pan-TRK IHC staining protocols and interpretation. As a reference method, the VENTANA pan-TRK Assay (clone EPR17341) on the Benchmark Ultra platform was selected. Six samples were selected: 2 negative, 2 fusion positive and 2 samples with wild-type endog...
Immunohistochemistry as a screening tool for NTRK gene fusions: results of a first Belgian ring trial
...
A Belgian ring trial for pan-TRK immunohistochemistry (IHC) staining was organised to harmonise pan-TRK IHC staining protocols and interpretation. As a reference method, the VENTANA pan-TRK Assay (clone EPR17341) on the Benchmark Ultra platform was selected. Six samples were selected: 2 negative, 2 fusion positive and 2 samples with wild-type endog...
Validation of an antimicrobial susceptibility testing protocol for Brachyspira hyodysenteriae and Brachyspira pilosicoli...
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Brachyspira hyodysenteriae and Brachyspira pilosicoli cause economically important enteric disease in pigs. Treatment of these infections often includes antimicrobial administration, which can be most effective when therapeutic options are informed by antimicrobial susceptibility testing data. Here we describe a method for broth dilution antimicrob...
A European interlaboratory trial to evaluate the performance of different PCR methods for Mycoplasma bovis diagnosis
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Published in BMC Veterinary Research
BackgroundSeveral species-specific PCR assays, based on a variety of target genes are currently used in the diagnosis of Mycoplasma bovis infections in cattle herds with respiratory diseases and/or mastitis. With this diversity of methods, and the development of new methods and formats, regular performance comparisons are required to ascertain diag...
Interlaboratory Validation of a Method for Hepatitis E Virus RNA Detection in Meat and Meat Products
...Published in Food and Environmental Virology
Increasing numbers of hepatitis E cases are currently recognized in many European countries. The zoonotic hepatitis E virus (HEV) genotype 3 mainly circulates in domestic pigs and wild boars, and can be transmitted to humans via consumption of insufficiently heated meat or meat products produced from those animals. Here, a detailed protocol for det...
