Worboys, Michael Toon, Elizabeth
Published in
History and Philosophy of the Life Sciences
Since the arrival of Translational Medicine (TM), as both a term and movement in the late 1990s, it has been associated almost exclusively with attempts to accelerate the “translation” of research-laboratory findings to improve efficacy and outcomes in clinical practice (Krueger et al. in Hist Philos Life Sci 41:57, 2019). This framing privileges o...
Alsharief, Alaa N. Laxer, Ronald M. Wang, Qiuyan Stimec, Jennifer Man, Carina Babyn, Paul Doria, Andrea S.
Published in
Insights into Imaging
Purpose1. To review the contemporary literature and present a list of the imaging findings for patients with autoinflammatory diseases from our hospital. All these patients are found to have a genetic mutation that is responsible for their disease.2. To present follow-up imaging findings, when available, and correlate those with symptoms and type o...
Bech, Bianca Lykkegaard, Jens Jørgen Lundbak, Tine Schrøder, Heidi Morsø Birkeland, Line Mette Schlyter, Mette Lund Hansen, Lotte Hanne Dalsgaard, Lillian Esbensen, Bente Appel
Published in
BMC Rheumatology
BackgroundInflammatory Arthritis is characterized by lifelong medical treatment and an unpredictable trajectory because of the fluctuating nature of the diseases. Proactive disease management is recommended, which includes close monitoring of disease activity that traditionally has been ensured by outpatient visits to rheumatologists at various fix...
Caffarelli, Carlo Santamaria, Francesca Mirra, Virginia Bacchini, Ermanno Santoro, Angelica Bernasconi, Sergio Corsello, Giovanni
Published in
Italian Journal of Pediatrics
We highlight the main developments that have been published during the first semester of the last year in the Italian Journal of Pediatrics. We have carefully chosen information from numerous exciting progresses issued in the Journal in the field of allergy, endocrinology, gastroenterology, neonatology, nutrition, nephrology, neurology, public heal...
Harkey, Matthew S. Lapane, Kate L. Liu, Shao-Hsien Lo, Grace H. McAlindon, Timothy E. Driban, Jeffrey B.
OBJECTIVE: To determine if a one-year change in walking speed is associated with receiving an incident knee replacement during the following year in adults with and at risk for knee osteoarthritis (OA). METHODS: Using data from the Osteoarthritis Initiative, we determined a one-year change in 20- meter walk speed from three observation periods (i.e...
Joo, Woojin Almario, Christopher V. Ishimori, Mariko Park, Yujin Jusufagic, Alma Noah, Benjamin Gensler, Lianne S. Venuturupalli, R. Swamy Kay, Jonathan Weisman, Michael H.
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OBJECTIVE: The number of therapies for axial spondyloarthritis (axSpA) is increasing. Thus, it has become more challenging for patients and physicians to navigate the risk-benefit profiles of the various treatment options. In this study, we used conjoint analysis-a form of trade-off analysis that elucidates how people make complex decisions by bala...
Bergstra, Sytske Anne Allaart, Cornelia F. Vega-Morales, David De Buck, Marieke Murphy, Elizabeth Salomon-Escoto, Karen I. Huizinga, Tom W. J.
OBJECTIVES: To study whether there is an association between body mass index (BMI) category and survival of various tumour necrosis factor inhibitors (TNFi) in rheumatoid arthritis (RA) patients in a real-life longitudinal international registry. METHODS: Data from 5230 patients with RA starting treatment with any TNFi were selected from the METEOR...
Sinha, Shubhadeep Ghosh, Biswadip Bandyopadhyay, Syamasis Fatima, Firdaus Bandi, Vamsi Krishna Thakur, Pankaj Reddy, Bala Chary, Sreenivasa Talluri, Leela Gupta, Ajay
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Published in
BMC Rheumatology
BackgroundOur study aimed to compare efficacy and safety of Hetero’s adalimumab (Mabura®, Hetero Biopharma Limited) versus reference adalimumab (Humira®, Abbvie Inc.) in Indian patients with active rheumatoid arthritis (RA) concomitant on methotrexate (MTX) therapy.MethodsPatients (n = 168) were randomized (2:1) to receive either test or reference ...
Nicolaou, O Sokratous, K Makowska, Z Morell, M De Groof, A Montigny, P Hadjisavvas, A Michailidou, K Oulas, A Spyrou, GM
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Background Approximately 50% of systemic lupus erythematosus (SLE) patients develop nephritis, which is among the most severe and frequent complications of the disease and a leading cause of morbidity and mortality. Despite intensive research, there are still no reliable lupus nephritis (LN) markers in clinical use that can assess renal damage and ...
Smolen, Josef S; Landewe, Robert BM; Bijlsma, Johannes WJ; Burmester, Gerd R; Dougados, Maxime; Kerschbaumer, Andreas; McInnes, Iain B; Sepriano, Alexandre; van Vollenhoven, Ronald F; de Wit, Maarten;
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OBJECTIVES: To provide an update of the European League Against Rheumatism (EULAR) rheumatoid arthritis (RA) management recommendations to account for the most recent developments in the field. METHODS: An international task force considered new evidence supporting or contradicting previous recommendations and novel therapies and strategic insights...
