Pompilus, Farrah Ciesluk, Anna Strzok, Sara Ciaravino, Valerie Harris, Kristina Szegvari, Boglarka Mountian, Irina Cleanthous, Sophie Meunier, Juliette
Published in
Health and Quality of Life Outcomes
BackgroundPatient-reported outcome (PRO) instruments provide robust and effective means of evaluating patients’ treatment experience; however, none adequately cover experience using self-injection devices with enhanced features, such as an electromechanical autoinjector (e-Device). The aim of this study was to develop a PRO instrument that accurate...
Bonfá, Eloisa Gossec, Laure Isenberg, David A. Li, Zhanguo Raychaudhuri, Soumya
Published in
Nature Reviews. Rheumatology
Eloisa Bonfá is a full professor of rheumatology and the clinical director of the largest tertiary public hospital of Latin America. Her main clinical and research interests are systemic lupus erythematosus and autoimmunity, with relevant contributions in the fields of autoantibodies, vaccines and drug monitoring in autoimmune diseases. She graduat...
Bender, Tim T. A. Leyens, Judith Sellin, Julia Kravchenko, Dmitrij Conrad, Rupert Mücke, Martin Seidel, Matthias F.
Published in
Orphanet Journal of Rare Diseases
BackgroundRare diseases (RDs) in rheumatology as a group have a high prevalence, but randomized controlled trials are hampered by their heterogeneity and low individual prevalence. To survey the current evidence of pharmacotherapies for rare rheumatic diseases, we conducted a systematic review and meta-analysis. Randomized controlled trials (RCTs) ...
Hayashi, Keigo Sada, Ken-Ei Asano, Yosuke Asano, Sumie Hiramatsu Yamamura, Yuriko Ohashi, Keiji Morishita, Michiko Watanabe, Haruki Narazaki, Mariko Matsumoto, Yoshinori
...
Published in
Scientific Reports
Renal impairment is a major concern in patients taking high-dose methotrexate (MTX) for malignancy, but it has not been fully explored in rheumatoid arthritis (RA) patients taking low-dose MTX. This study aimed to elucidate the dose-dependent effects of MTX on the renal function of patients with RA. We retrospectively reviewed 502 consecutive RA pa...
Shih, Liang-Chun Hsieh, Hua-Hsin Tsay, Gregory J. Lee, Ivan T. Tsou, Yung-An Lin, Cheng-Li Shen, Te-Chun Bau, Da-Tian Tai, Chih-Jaan Lin, Chia-Der
...
Published in
Scientific Reports
Evidence shows that chronic rhinosinusitis (CRS) is associated with prior presence of autoimmune diseases; however, large-scale population-based studies in the literature are limited. We conducted a population-based case–control study investigating the association between CRS and premorbid autoimmune diseases by using the National Health Insurance ...
Abuhelwa, Ahmad Y. Hopkins, Ashley M. Sorich, Michael J. Proudman, Susanna Foster, David J. R. Wiese, Michael D.
Published in
Scientific Reports
The aim of this study was to investigate the association between body-mass index (BMI) and remission in RA patients receiving conventional synthetic (cs-) or the biological Disease-Modifying Antirheumatic Drug (DMARD), tocilizumab. Individual participant data (IPD) were pooled from five trials investigating tocilizumab and/or csDMARDs therapy (prim...
Ciaffi, Jacopo Meliconi, Riccardo Ruscitti, Piero Berardicurti, Onorina Giacomelli, Roberto Ursini, Francesco
Published in
BMC Rheumatology
BackgroundDifferent proportions of musculoskeletal or autoimmune manifestations associated with COVID-19 have been reported in literature. We performed a systematic review and meta-analysis with the aim of assessing the prevalence of rheumatic manifestations in patients affected by COVID-19, as initial symptom or during disease course.MethodsA data...
Romano, Micol Piskin, David Berard, Roberta A. Jackson, Bradley C. Acikel, Cengizhan Carrero, Juan J. Lachmann, Helen J. Yilmaz, Mahmut I. Demirkaya, Erkan
Published in
Scientific Reports
Chronic inflammation and proteinuria is a risk factor for cardiovascular disease (CVD) in patients with chronic kidney diseases and rheumatologic disorders. Our aim was to investigate the CVD events (CVDEs) and survival between the patients with FMF-related AA amyloidosis and glomerulonephropathies (GN) to define possible predictors for CVDEs. A pr...
Triguero-Martínez, Ana de la Fuente, Hortensia Montes, Nuria Ortiz, Ana María Roy-Vallejo, Emilia Castañeda, Santos González-Alvaro, Isidoro Lamana, Amalia
Published in
Scientific Reports
Galectin 1 (Gal1) is a lectin with a wide cellular expression that functions as a negative regulator of the immune system in several animal models of autoimmune diseases. Identification of patients with rheumatoid arthritis (RA) has improved during the last decade, although there is still a need for biomarkers allowing an early diagnosis. In this r...
Dey, Mrinalini Zhao, Sizheng Steven
Published in
Rheumatology International
Patient and public involvement is essential in the design and implementation of research studies to ensure research remains relevant and in line with public priorities. Public views on a given area of research may be sought via platforms such as focus groups or surveys. Here, we present the use of an openly available Google search data query tool, ...
