Combe, Bernard Allanore, Yannick Alten, Rieke Caporali, Roberto Durez, Patrick Iannone, Florenzo Nurmohamed, Michael T. Toumi, Mondher Lee, Sang Joon Kwon, Taek Sang
...
Published in
Arthritis Research & Therapy
BackgroundA subcutaneous (SC) formulation of infliximab biosimilar CT-P13 is approved in Europe for the treatment of adult patients with rheumatoid arthritis (RA). It may offer improved efficacy versus intravenous (IV) infliximab formulations.MethodsA network meta-regression was conducted using individual patient data from two randomised trials in ...
Rayner, Fiona Anderson, Amy E. Baker, Kenneth F. Buckley, Christopher D. Dyke, Bernard Fenton, Sally Filer, Andrew Goodyear, Carl S. Hilkens, Catharien M. U. Hiu, Shaun
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Published in
BMC Rheumatology
BackgroundOur knowledge of immune-mediated inflammatory disease (IMID) aetiology and pathogenesis has improved greatly over recent years, however, very little is known of the factors that trigger disease relapses (flares), converting diseases from inactive to active states. Focussing on rheumatoid arthritis (RA), the challenge that we will address ...
Wu, Rui Long, Li Zhou, Qiao Su, Jiang Su, Wei Zhu, Jing
Published in
Journal of Orthopaedic Surgery and Research
BackgroundRheumatoid arthritis (RA) is a common chronic autoimmune disease characterized by inflammation of the synovial membrane. However, the etiology and underlying molecular events of RA are unclear. Here, we applied bioinformatics analysis to identify the key genes involved in RA.MethodsGSE77298 was downloaded from the Gene Expression Omnibus ...
Mathias, Kristen Amarnani, Abhimanyu Pal, Neha Karri, Jay Arkfeld, Daniel Hagedorn, Jonathan M. Abd-Elsayed, Alaa
Published in
Current Pain and Headache Reports
Purpose of ReviewChronic pain is highly prevalent in patients with rheumatoid arthritis (RA) and can cause various physical and psychological impairments. Unfortunately, the appropriate diagnosis of chronic pain syndromes in this population can be challenging because pain may be primary to RA-specific inflammation and/or secondary to other conditio...
Hu, Chao-Jun Zhang, Li Zhou, Shuang Jiang, Nan Zhao, Jiu-Liang Wang, Qian Tian, Xin-Ping Zeng, Xiao-Feng
Published in
Journal of Orthopaedic Surgery and Research
BackgroundThis study aims to evaluate the efficacy and safety of the iguratimod (IGU) as monotherapy or combined therapy in patients with rheumatoid arthritis (RA) by using meta-analysis.MethodsWe searched Medline, EMBASE, Cochrane library, CNKI, Wanfang medical network from initial to 30 June, 2020, for randomized clinical trials (RCTs). Two autho...
Luo, Huifang Peng, Jie Ma, Qing Wei, Zhihua Lin, Changsong Zhang, Mingying Li, Peiwu Song, Yang Yang, Xiangwei
Published in
Trials
BackgroundRheumatoid arthritis (RA) is a common autoimmune disease that severely impacts quality of life. Currently available medications for the treatment of RA have adverse side effects. Emerging evidence suggests that intradermal acupuncture (IA) is feasible and safe for patients, but its application in RA patients has not been examined. Our stu...
Andonian, Brian J. Johannemann, Andrew Hubal, Monica J. Pober, David M. Koss, Alec Kraus, William E. Bartlett, David B. Huffman, Kim M.
Published in
Arthritis Research & Therapy
BackgroundExercise training, including high-intensity interval training (HIIT), improves rheumatoid arthritis (RA) inflammatory disease activity via unclear mechanisms. Because exercise requires skeletal muscle, skeletal muscle molecular pathways may contribute. The purpose of this study was to identify connections between skeletal muscle molecular...
Huang, Yu Zhang, Zheng Zheng, Youli Zhao, Zhulan Zhong, Yang Zhang, Qingyu Xia, Degeng Ma, Ning Zhang, Li
Published in
BMC Oral Health
BackgroundsTo date, there is still no consensus about the clinical efficacy of non-surgical periodontal therapy in rheumatoid arthritis (RA) patients with periodontitis. Therefore, the aim of this study was to summarize clinical data regarding the efficacy of scaling and root planing (SRP) in patients with RA and periodontitis compared to non-RA pe...
Jung, Sang Youn Koh, Jung Hee Kim, Ki-Jo Park, Yong-Wook Yang, Hyung-In Choi, Sung Jae Lee, Jisoo Choi, Chan-Bum Kim, Wan-Uk
Published in
Arthritis Research & Therapy
BackgroundTapering or stopping biological disease-modifying anti-rheumatic drugs has been proposed for patients with rheumatoid arthritis (RA) in remission, but it frequently results in high rates of recurrence. This study evaluates the efficacy and safety of tacrolimus (TAC) as maintenance therapy in patients with established RA in remission after...
Ruscitti, Piero Conforti, Alessandro Cipriani, Paola Giacomelli, Roberto Tasso, Marco Costa, Luisa Caso, Francesco
Published in
Advances in Rheumatology
As the coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to spread rapidly, there are still many unresolved questions of how this virus would impact on autoimmune inflammatory joint diseases and autoinflammatory disorders. The main aim of this paper is to describe the main ...
