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with Retinoic acid receptor γ as keyword
Koterazawa, Yasufumi Koyanagi-Aoi, Michiyo Uehara, Keiichiro Kakeji, Yoshihiro Aoi, Takashi
Published in
Journal of Gastroenterology
BackgroundThe esophagus is known to be derived from the foregut. However, the mechanisms regulating this process remain unclear. In particular, the details of the human esophagus itself have been poorly researched. In this decade, studies using human induced pluripotent stem cells (hiPSCs) have proven powerful tools for clarifying the developmental...
Kitakaze, Tomoya Yoshikawa, Miki Kobayashi, Yasuyuki Kimura, Naohiro Goshima, Naoki Ishikawa, Takahiro Ogata, Yoshiyuki Yamashita, Yoko Ashida, Hitoshi Harada, Naoki
...
Published in
Biochimica et biophysica acta. Molecular cell research
Skeletal muscle secretes biologically active proteins that contribute to muscle hypertrophy in response to either exercise or dietary intake. The identification of skeletal muscle-secreted proteins that induces hypertrophy can provide critical information regarding skeletal muscle health. Dietary provitamin A, β-carotene, induces hypertrophy of the...
Huang, Gui-Li Song, Wei Zhou, Pan Fu, Qi-Rui Lin, Chen-Lu Chen, Qing-Xi Shen, Dong-Yan
Published in
Cell cycle (Georgetown, Tex.)
Retinoic acid receptor γ (RARγ), a unique member of the nuclear receptor superfamily, plays an important role in the progression of several cancers such as hepatocellular carcinoma, esophageal cancer, and cholangiocarcinoma. However, little is known about the regulatory mechanism of the RARγ expression in colorectal cancer (CRC) progression. In the...
Sakamoto, Shuichi Kojima, Fukiko Momose, Isao Kawada, Manabu Adachi, Hayamitsu Nishimura, Yoshio
Published in
Biochemical and Biophysical Research Communications
Decalpenic acid is a natural small molecule previously isolated from the fermentation broth of fungi that induces early osteoblastic markers in pluripotent mesenchymal cells. Treatment of mouse pluripotent mesenchymal C3H10T1/2 cells with decalpenic acid gave rise to a morphological change similar to that induced by the treatment with retinoic acid...
Gordy, Claire Dzhagalov, Ivan He, You-Wen
Published in
Seminars in immunology
Retinoic acid plays a key role in the development and function of the immune system; however, the contribution of each of the three retinoic acid receptors (RARs) to the T cell immune response is not yet well understood. Of these receptors, both RARα and RARγ are expressed in T lymphocytes. While possible functional redundancy thus complicates unde...
