Interdisciplinary weight loss and lifestyle intervention for obstructive sleep apnoea: the INTERAPNEA randomised clinica...
Published in British journal of sports medicine
Off-pump lung re-transplantation avoiding clamshell thoracotomy is feasible and safe: a single-center experience
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BACKGROUND: Lung re-transplantation (re-LTx) is the only therapeutic option for selected patients with advanced allograft dysfunction. This study aims to describe our center's experience to illustrate the feasibility and safety of off-pump re-LTx avoiding clamshell incision. METHODS: We performed a retrospective analysis of 42 patients who underwen...
Pacemaker after Sutureless and Rapid-Deployment Prostheses: A Progress Report from the SURD-IR
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OBJECTIVES: The aim of this study was to investigate the need for postoperative permanent pacemaker implantation (PPI) following sutureless and rapid-deployment aortic valve replacement (SuRD-AVR) in the context of a progress report from a large multicenter international registry (SURD-IR). METHODS: We retrospectively analyzed 4,166 patients who un...
A LASSO-DERIVED PREDICTIVE MODEL FOR POSTOPERATIVE RESPIRATORY FAILURE IN A HETEROGENEOUS ADULT ELECTIVE SURGERY PATIENT...
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The contribution of microvascular free flaps and pedicled flaps to successful chest wall surgery
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OBJECTIVE: Pedicled flaps (PFs) have historically served as the preferred option for reconstruction of large chest wall defects. More recently, the indications for microvascular-free flaps (MVFFs) have increased, particularly for defects in which PFs are inadequate or unavailable. We sought to compare oncologic and surgical outcomes between MVFFs a...
Effects of inspiratory muscle training on exertional breathlessness in patients with unilateral diaphragm dysfunction: a...
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BACKGROUND: Unilateral diaphragm dysfunction (UDD) is an underdiagnosed cause of dyspnoea. Inspiratory muscle training (IMT) is the only conservative treatment for UDD, but the mechanisms of improvement are unknown. We characterised the effects of IMT on dyspnoea, exercise tolerance and respiratory muscle function in people with UDD. METHODS: 15 pe...
Prevalence of dyspnea in general adult populations: a systematic review and meta-analysis
Introduction Dyspnea is a commonly described symptom in various chronic and acute conditions. Despite its frequency, relatively little is known about the prevalence and assessment of dyspnea in general populations. The aims of this review were: 1) to estimate the prevalence of dyspnea in general adult populations; 2) to identify associated factors;...
In vivo performance of a tri-leaflet mechanical heart valve prosthesis in an ovine model
OBJECTIVES: We present the long-term results of a trileaflet (Triflo) versus bileaflet (On-X) mechanical valve in both aortic and pulmonary positions in a sheep model. METHODS: The Triflo valve was implanted in 21 female sheep in aortic (n = 8) and pulmonary position (n = 13). The On-X valve was implanted in 7 female sheep in aortic (n = 1) and pul...
Work of Breathing During Proportional Assist Ventilation as a Predictor of Extubation Failure.
BackgroundDespite decades of research on predictors of extubation success, use of ventilatory support after extubation is common and 10-20% of patients require re-intubation. Proportional assist ventilation (PAV) mode automatically calculates estimated total work of breathing (total WOB). Here, we assessed the performance of total WOB to predict ex...
COVID-19 progression in hospitalized patients using follow-up in vivo CT and ex vivo microCT
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BACKGROUND: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes coronavirus disease-19 (COVID-19) which can lead to acute respiratory distress syndrome (ARDS) and evolve to pulmonary fibrosis. Computed tomography (CT) is used to study disease progression and describe radiological patterns in COVID-19 patients. This study aimed to as...
