Published in Cell Death & Disease
Acute respiratory distress syndrome (ARDS) is common in intensive care units (ICUs), although it is associated with high mortality, no effective pharmacological treatments are currently available. Despite being poorly understood, the role of programmed cell death protein 1 (PD-1) and PD-ligand 1 (PD-L1) axis in ARDS may provide significant insights...
Published in Scientific Reports
Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, and fatal lung disease. This disease is characterized by an excessive accumulation of extracellular matrix deposition that modify normal lung physiology. Up to date, there are not efficient therapeutic tools to fight IPF. Glucagon-like peptide-1 receptor (GLP-1R) activation plays an ess...
Published in Journal of Hydrology and Hydromechanics
Dew is commonly regarded as an important water source for lichens. This is also the case for crustose lichens that are attached to the substrate, whether rocks or soil. While being verified during ample research on rock-dwelling lichens in the Negev, the findings from soil-dwelling lichens (lichen biocrusts) are not conclusive. In the Tabernas Dese...
Published in Nature Communications
Functional connectivity measured from fMRI data is widely used in neuroscience. Here the authors report an association between two types of breathing signature and obtained BOLD data, and associated sex differences.
Published in Communications Biology
Minako Okazaki et al. show that blockade of cystathionine β-synthase, which produces H2S gas, evoked gasping in an in situ arterially perfused preparation of decerebrated rats, whereas inhibition of cystathionine γ-lyase produced no response. These results highlight the importance of endogenous H2S in maintaining eupnea at the respiratory center.
Published in Scientific Reports
The mutualistic relationship existing between scleractinian corals and their photosynthetic endosymbionts involves a complex integration of the metabolic pathways within the holobiont. Respiration and photosynthesis are the most important of these processes and although they have been extensively studied, our understanding of their interactions and...
Published in Scientific Reports
The use of inhalational anaesthesia is ubiquitous in terrestrial vertebrates. Given the dependence of these agents on delivery by the cardiorespiratory system, we developed a new computational model predicting equilibration of inhaled anaesthetics in mammalian and ectotherm conditions including the ability of reptiles to maintain vascular shunts. A...
Published in Scientific Reports
Trace metal contamination in the aquatic ecosystem occurs worldwide: although copper is an essential trace metal, it is considered as a pollutant at certain levels in China. Freshwater crayfish Cambaroides dauricus is a commercially important wild species in northeastern China, in which is an important heavy industry area. The population of C. daur...
Published in Scientific Reports
Area under expiratory flow-volume curve (AEX) has been proposed recently to be a useful spirometric tool for assessing ventilatory patterns and impairment severity. We derive here normative reference values for AEX, based on age, gender, race, height and weight, and by using artificial neural network (ANN) algorithms. We analyzed 3567 normal spirom...
Published in Microbial ecology
Invasive terrestrial isopods are likely to have altered leaf litter decomposition processes in North American forests, but the mechanisms underlying these alterations and the degree to which they differ among isopod species are poorly characterized. Using mixed-deciduous leaf litter microcosms, we quantified the effects of two common, invasive isop...
