Gevaert, Julia J Fink, Corby Dikeakos, Jimmy D Dekaban, Gregory A Foster, Paula J
Published in
Molecular imaging and biology
The purpose of this study was to evaluate magnetic particle imaging (MPI) as a method for the in vivo tracking of dendritic cells (DC). DC are used in cancer immunotherapy and must migrate from the site of implantation to lymph nodes to be effective. The magnitude of the ensuing T cell response is proportional to the number of lymph node-migrated D...
Liang, Nuanyi Emami, Shiva Patten, Kelley T Valenzuela, Anthony E Wallis, Christopher D Wexler, Anthony S Bein, Keith J Lein, Pamela J Taha, Ameer Y
Chronic exposure to traffic-related air pollution (TRAP) is known to promote systemic inflammation, which is thought to underlie respiratory, cardiovascular, metabolic and neurological disorders. It is not known whether chronic TRAP exposure dampens inflammation resolution, the homeostatic process for stopping inflammation and repairing damaged cel...
Hiram, Roddy
Published in
Molecular biology reports
Chronic heart diseases have in common an unresolved inflammatory status. In atherosclerosis, myocarditis, myocardial infarction, or atrial fibrillation, mounting evidence suggests that unresolved inflammation contributes to the chronicity, aggravation, and morbidity of the disease. Following cardiac injury or infection, acute inflammation is a norm...
Kain, Vasundhara Mat, Yusuf Halade, Ganesh V
Published in
GeroScience
In the process of physiological cardiac repair, splenic leukocyte-activated lipoxygenases (LOXs) are essential for the biosynthesis of specialized pro-resolving lipid mediators as a segment of an active process of acute inflammation in splenocardiac manner. In contrast, young 12/15LOX-/- mice use a compensatory mechanism that amplifies epoxyeicosat...
Albaba, Isam Medarov, Boris I.
Published in
Respiratory Medicine Case Reports
Pulmonary hypertension (PH) in cancer patients can be caused by several mechanisms. It can be a direct cancer effect through pulmonary tumor thrombotic microangiopathy, pulmonary tumor emboli, extrinsic compression, intravascular tumors, or a secondary consequence of therapy, including chemotherapy agents, radiation, and stem cell transplantation. ...
Pistorius, Kimberly Ly, Lucy Souza, Patricia R Gomez, Esteban A Koenis, Duco S Rodriguez, Ana R Foster, Julie Sosabowski, Jane Hopkinson, Mark Rajeeve, Vinothini
...
Published in
EBioMedicine
Rheumatoid arthritis (RA) is a progressive degenerative disorder that leads to joint destruction. Available treatments only target the inflammatory component with minimal impact on joint repair. We recently uncovered a previously unappreciated family of pro-resolving mediators, the maresin conjugate in tissue regeneration (MCTR), that display both ...
Wang, Xinyi Yin, Longfei Wu, Guohua Luo, Bin Yin, Pengqi
Published in
Journal of Physics: Conference Series
This paper presents a new scheme to improve the imaging resolution of optical fiber endoscope. Multimode fiber imaging is combined with correlation imaging experimental architecture, and Schmidt orthogonalization algorithm is used to reduce the correlation of light field. The simulation and experimental results show that this scheme can greatly imp...
Naqvi, Raza Ali Gupta, Meenal George, Anne Naqvi, Afsar R
Published in
Seminars in cell & developmental biology
Inflammation is a host defense mechanism orchestrated through imperative factors - acute inflammatory responses mediated by cellular and molecular events leading to activation of defensive immune subsets - to marginalize detrimental injury, pathogenic agents and infected cells. These potent inflammatory events, if uncontrolled, may cause tissue dam...
Enmark, Martin Häggström, Jakob Samuelsson, Jörgen Fornstedt, Torgny
Published in
Journal of chromatography. A
Support vector regression models are created and used to predict the retention times of oligonucleotides separated using gradient ion-pair chromatography with high accuracy. The experimental dataset consisted of fully phosphorothioated oligonucleotides. Two models were trained and validated using two pseudo-orthogonal gradient modes and three gradi...
DeBolt, Chelsea A Sarker, Minhazur Cohen, Natalie Kaplowitz, Elianna Buckley, Ayisha Stone, Joanne Bianco, Angela
Published in
European journal of obstetrics, gynecology, and reproductive biology
To determine if early-onset fetal growth restriction with abnormal individual biometric parameters, defined as head circumference, abdominal circumference and femur length less than the 10th percentile, is associated with adverse neonatal outcomes compared to fetal growth restriction with normal biometric parameters. Retrospective cohort study incl...
