Abstract: Objectives: This note describes a free online portal (www.therandomiser.co.uk) that allows researchers to design randomised controlled trials and then delegate the random assignment process to pracademics delivering the experiment. Methods: Observation of the use of this tool in repeated randomised trials in police agencies. Findings: Res...
Abstract: Research Question: Can criminal recruiters be identified and ranked by crime harm levels in a London borough, and if so, how long is the predictive window of opportunity for targeting them with crime prevention efforts? Data: This study deploys 5 years of Metropolitan Police Service crime data, relating to one of the 32 London boroughs in...
Funder: University of Cambridge / Abstract: Research Question: To what extent are victims of violent crime also offenders, and vice versa, with what concentrations of total crime harm across each person who has ever been reported as both a victim and an offender within the study period? Data: We analyse 27,233 unique individuals who were the subjec...
Funder: University of Cambridge / Abstract: Research question: Given the information available to Devon and Cornwall Police at the time when they received a missing person report, which knowable variables indicated increased odds of the person coming to serious harm? Data: The study examines all 92,681 missing reports received by Devon and Cornwall...
Published in BMC Public Health
BackgroundA wide range of diseases show some degree of clustering in families; family history is therefore an important aspect for clinicians when making risk predictions. Familial aggregation is often quantified in terms of a familial relative risk (FRR), and although at first glance this measure may seem simple and intuitive as an average risk pr...
Magnitude of intracranial pressure (ICP) elevations and their duration have been associated with worse outcomes in patients with traumatic brain injuries (TBI), however published thresholds for injury vary and uncertainty about these levels has received relatively little attention. In this study, we have analyzed high-resolution ICP monitoring data...
Small (s)RNAs play crucial roles in the regulation of gene expression and genome stability across eukaryotes where they direct epigenetic modifications, post-transcriptional gene silencing, and defense against both endogenous and exogenous viruses. It is known that Chlamydomonas reinhardtii, a well-studied unicellular green algae species, possesses...
Background: Despite a growing body of evidence suggesting that short sleep duration may be linked to adverse metabolic outcomes, how these associations differ between age groups remains unclear. We use eight years of data from the UK National Diet and Nutritional Survey (NDNS) (2008–2016) to analyse cross-sectional relationships between sleep durat...
Funder: Cancer Research UK / Funder: Breast Cancer Now / Funder: Addenbrookes Charitable Trust / Funder: Mark Foundation For Cancer Research; doi: http://dx.doi.org/10.13039/100014599 / Funder: Addenbrooke's Charitable Trust, Cambridge University Hospitals (GB) / Abstract: Background: NRG1 gene fusions may be clinically actionable, since cancers ca...
Funder: University of Cambridge / Abstract: Research Question: Based on the evidence at the end of a preliminary investigation of minor, non-domestic assault and public order cases, how accurately can the likelihood of a sanctioned detection be predicted for triage decisions while maintaining high awareness of legitimacy issues? Data: Investigative...
