Parenti, Mariana Slupsky, Carolyn M
Pregnancy is a time of high metabolic coordination, as maternal metabolism adapts to support the growing fetus. Many of these changes are coordinated by the placenta, a critical fetal endocrine organ and the site of maternal-fetal crosstalk. Dysregulation in maternal and placental metabolism during pregnancy has been linked to adverse outcomes, inc...
Kumar, Ravinder Oke, Ashwini Rockmill, Beth de Cruz, Matthew Verduzco, Rafael Shodhan, Anura Woodruff-Madeira, Xavier Abrahamsson, Dimitri P Varshavsky, Julia Lam, Juleen
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Infertility affects ∼12 % of couples, with environmental chemical exposure as a potential contributor. Of the chemicals that are actively manufactured, very few are assessed for reproductive health effects. Rodents are commonly used to evaluate reproductive effects, which is both costly and time consuming. Thus, there is a pressing need for rapid m...
Joseph Davey, Dvora Dadan, Sumaya Bheemraj, Kalisha Waitt, Catriona Khoo, Saye Myer, Landon Wiesner, Lubbe Else, Laura Thompson, Beth Castel, Sandra
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BackgroundThere are few data on tenofovir-diphosphate (TFV-DP) concentrations in pregnant and postpartum women on Tenofovir Disoproxil Fumarate-Emtricitabine (TDF-FTC) or Tenofovir Alafenamide-Emtricitabine (TAF-FTC).MethodsEligible pregnant women were randomized to TDF-FTC or TAF-FTC and followed for 16 weeks (8-weeks pregnant, 8-weeks postpartum)...
Schwarz, Eleanor Bimla Chiang, Amy Yunyu Lewis, Carrie A Gariepy, Aileen M Reeves, Matthew F
BackgroundTubal sterilization is the most commonly used method of contraception in the United States. Because contraceptive effectiveness influences contraceptive selection, we examined typical use failure rates after tubal sterilization in the United States.MethodsWe estimated rates of pregnancy after tubal sterilization using data from four waves...
Babey, Muriel E Krause, William C Chen, Kun Herber, Candice B Torok, Zsofia Nikkanen, Joni Rodriguez, Ruben Zhang, Xiao Castro-Navarro, Fernanda Wang, Yuting
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In lactating mothers, the high calcium (Ca2+) demand for milk production triggers significant bone loss1. Although oestrogen normally counteracts excessive bone resorption by promoting bone formation, this sex steroid drops precipitously during this postpartum period. Here we report that brain-derived cellular communication network factor 3 (CCN3) ...
Creinin, Mitchell D
Burns, Christina Bakaj, Angela Berishaj, Amonda Hristidis, Vagelis Deak, Pamela Equils, Ozlem
BackgroundPatients find technology tools to be more approachable for seeking sensitive health-related information, such as reproductive health information. The inventive conversational ability of artificial intelligence (AI) chatbots, such as ChatGPT (OpenAI Inc), offers a potential means for patients to effectively locate answers to their health-r...
Moy, Jeffrey Landon, Matthew Vigilante, John Lehmann, Benjamin DeChambeau, Amber Rohlfing, Frederick Marks, Robert
PurposeThe aim of this study is to prospectively evaluate whether women with copper-containing intrauterine devices (Cu-IUD), currently listed as MR conditional, can safely undergo 3.0 Tesla (3 T) magnetic resonance imaging (MRI).Methods73 women, age 18-54 years old, with a Cu-IUD who were undergoing MRI for any reason were included consecutively. ...
Ramirez, Raymi O Sung, Kyunghyun
Naciri, Ikrame Andrade-Ludena, Maria D Yang, Ying Kong, Mei Sun, Sha
The prevalence and progression of cancer differ in males and females, and thus, sexual dimorphism in tumor development directly impacts clinical research and medicine. Long non-coding RNAs (lncRNAs) are increasingly recognized as important players in gene expression and various cellular processes, including cancer development and progression. In re...