Di Poi, Emma Colussi, GianLuca Bertoni, Martina Giovannini, Ivan Tolusso, Barbara Ferraccioli, Gian Franco Gremese, Elisa De Vita, Salvatore Romano, Giulio
Published in
Kidney and Blood Pressure Research
Introduction: If properly evaluated, chronic kidney disease can be found in up to 50% of patients with systemic sclerosis (SSc). The renal resistive index (RRI) is a marker of intrarenal vascular resistance and can predict SSc-associated vasculopathy. This study aimed to determine the impact of bosentan, a nonselective endothelin-1 receptor antagon...
Kato, Sawako Kuwatsuka, Yachiyo Ando, Masahiko Tatematsu, Yoshitaka Nishibori, Nobuhiro Maruyama, Shoichi
Published in
BMC nephrology
Sodium-glucose cotransporter 2 inhibitors (SGLT2i) are considered to have the potential to maintain renal function by correcting glomerular hypertension in patients with diabetic kidney disease (DKD). The aim of this study is to demonstrate the renoprotective effect of SGLT2i by measuring renal hemodynamics, including glomerular filtration fraction...
Williams, Jan M Murphy, Sydney R Wu, Wenjie Border, Jane J Fan, Fan Roman, Richard J
Published in
GeroScience
Diabetes, hypertension, and aging are major contributors to cardiovascular and chronic kidney disease (CKD). Sodium/glucose cotransporter 2 (SGLT2) inhibitors have become a preferred treatment for type II diabetic patients since they have cardiorenal protective effects. However, most elderly diabetic patients also have hypertension, and the effects...
Ardissino, Gianluigi Giussani, Antenore Capone, Valentina Testa, Sara Gandini, Cristiano Montini, Giovanni
Published in
Pediatric nephrology (Berlin, Germany)
Fenoldopam, a vasodilating agent, may represent a potential therapeutic opportunity to increase renal perfusion in those conditions where renal hemodynamics are severely impaired by vascular sub-occlusion, as, indeed, is the case in thrombotic microangiopathies. The renal resistance index (RRI) was measured, on and off fenoldopam, in 27 children wi...
Yang, Jing Yang, Shuohui Xu, Yizeng Lu, Fang You, Lan He, Zheng Zhan, Songhua Ye, Chaoyang Liu, Mengxiao Fu, Caixia
...
Published in
Nephron
Introduction: The basic pathophysiologic derangement of chronic kidney disease (CKD) begins with the loss of nephrons, leading to renal hemodynamic changes, eventually causing a reduced nephron count and renal hypoxia. The purpose of this study was to observe the renal oxygenation and renal hemodynamics of patients with CKD using blood oxygenation ...
Kannenkeril, Dennis Jung, Susanne Ott, Christian Striepe, Kristina Kolwelter, Julie Schmieder, Roland E. Bosch, Agnes
Published in
Kidney and Blood Pressure Research
Background: Chronic mental stress is recognized as a modifiable risk factor for cardiovascular disease. The aim of this study was to demonstrate that noise annoyance-induced stress is associated with changes in renal hemodynamics. Methods: Renal hemodynamic parameters were measured using steady-state input clearance with infusion of para-aminohippu...
Spit, Karlinde A Muskiet, Marcel H A Tonneijck, Lennart Smits, Mark M Kramer, Mark H H Joles, Jaap A de Boer, Anneloes van Raalte, Daniel H
Published in
Magma (New York, N.Y.)
Increased renal sinus fat (RSF) is associated with hypertension and chronic kidney disease, but underlying mechanisms are incompletely understood. We evaluated relations between RSF and gold-standard measures of renal hemodynamics in type 2 diabetes (T2D) patients. Fifty-one T2D patients [age 63 ± 7 years; BMI 31 (28-34) kg/m2; GFR 83 ± 16 mL/min/1...
Franco, Martha Pérez-Méndez, Oscar Kulthinee, Supaporn Navar, L Gabriel
Published in
Purinergic signalling
Glomerular arteriolar vasoconstriction and tubulointerstitial injury are observed before glomerular damage occurs in models of hypertension. High interstitial ATP concentrations, caused by the increase in arterial pressure, alter renal mechanisms involved in the long-term control of blood pressure, autoregulation of glomerular filtration rate and b...
Wolf, Victoria L. Ryan, Michael J.
Published in
Current Hypertension Reports
Purpose of ReviewTo highlight important new findings on the topic of autoimmune disease-associated hypertension.Recent FindingsAutoimmune diseases including systemic lupus erythematosus and rheumatoid arthritis are associated with an increased risk for hypertension and cardiovascular disease. A complex interaction among genetic, environmental, horm...
Bonsante, Francesco Ramful, Duksha Binquet, Christine Samperiz, Sylvain Daniel, Sandrine Gouyon, Jean-Bernard Iacobelli, Silvia
Published in
Neonatology
Background: Acute kidney injury (AKI) is a frequent complication in preterm infants, and the identification of early markers of renal hypoperfusion is a chief challenge in neonatal intensive care units. Objectives: To describe the association between early markers of cardiovascular function and renal perfusion with AKI occurrence in a cohort of pre...
