Furashova, Olga Strassburger, Patrick Becker, Klio Ai Engelmann, Katrin
Published in
BMC Ophthalmology
BackgroundTo evaluate if a combination therapy with micropulse diode laser (MPL) shows non-inferiority on visual acuity (BCVA) within 12 months in comparison to standard therapy, i.e. intravitreal injection of ranibizumab alone.SettingInstitutional. Prospective randomized single-center trial.MethodsPatients with diabetic macular edema (DME) receive...
Song, Shuang Yu, Xiaobing Zhang, Peng Gu, Xiaoya Dai, Hong
Published in
BMC Ophthalmology
BackgroundIt is not clear whether macular laser combined with anti-vascular endothelial growth factor (VEGF) can reduce the number of anti-VEGF injections in the treatment of macular edema (ME) secondary to branch retinal vein occlusion (BRVO). Our study aimed to investigate the effects of intravitreal ranibizumab with or without macular laser for ...
Lai, Kunbei Huang, Chuangxin Li, Longhui Gong, Yajun Xu, Fabao Zhong, Xiaojing Lu, Lin Jin, Chenjin
Published in
BMC Ophthalmology
BackgroundTo evaluate the anatomical and functional responses in eyes with diabetic macular edema (DME) treated with ranibizumab under “1 + pro re nata (PRN)” regimen.MethodsThis prospective interventional case series included 69 eyes of 69 patients with DME treated with intravitreal injections of 0.5 mg ranibizumab followed by repeated injections ...
Melo, Gustavo Barreto Ferreira, Magno Maia, Maurício
ABSTRACT Purpose: This survey aimed at assessing the clinical characteristics of patients with inflammatory reactions after intravitreal injection of antiangiogenic agents and the techniques employed by Brazilian retina specialists. Methods: We sent an 18-item questionnaire electronically to retina specialists who are using antiangiogenic agents. W...
Chatziralli, Irini Theodossiadis, George Dimitriou, Eleni Kazantzis, Dimitrios Theodossiadis, Panagiotis
Published in
International ophthalmology
To analyze photoreceptors' condition after intravitreal ranibizumab treatment according to the pattern of diabetic macular edema (DME) on spectral-domain optical coherence tomography (SD-OCT). Retrospective study includes 58 treatment naïve patients with DME, treated with intravitreal ranibizumab injections and followed up for at least 12 months. P...
de Sá Quirino-Makarczyk, Luciana Sainz Ugarte, Maria de Fátima Viana Vieira, Bruna Kniggendorf, Sérgio Saito Regatieri, Caio Vinicius
Published in
International Journal of Retina and Vitreous
BackgroundTo evaluate the change in best corrected visual acuity (VA) and central macular thickness (CMT) following treatment with intravitreal aflibercept (AFL) in patients poorly responders or non responders to ranibizumab (RBZ).MethodsCharts of patients injected with RBZ from January 2016 to December 2018 (548 cases) due to neovascular age-relat...
Pielen, Amelie Feltgen, Nicolas Hattenbach, Lars-Olof Hoerauf, Hans Bertelmann, Thomas Quiering, Claudia Vögeler, Jessica Priglinger, Siegfried Lang, Gabriele E Schmitz-Valckenberg, Steffen
...
Published in
Current eye research
Purpose: To compare ischemia-related clinical outcomes in patients treated with either ranibizumab pro re nata (PRN) or single dexamethasone implant in the Branch Retinal Vein Occlusion (COMRADE-B) or Central Retinal Vein Occlusion (COMRADE-C) trials.Methods: A post-hoc analysis of the Phase IIIb, 6-month, multicenter, double-masked, randomized, CO...
Stewart, Stephen Yeong, Jian Lee Virgili, Gianni Azuara-Blanco, Augusto Lois, Noemi
Published in
Retina (Philadelphia, Pa.)
To evaluate the pragmatism and generalizability of randomized clinical trials (RCTs) on ranibizumab for diabetic macular edema and determine whether clinical outcomes would differ based on whether or not patients fulfill the eligibility criteria of these RCTs. Pragmatism and generalizability of three RCTs on ranibizumab for diabetic macular edema (...
Ryu, Sun Young Kim, Jiwon Kim, Dong Wook Chung, Eun Jee
Published in
Korean Journal of Ophthalmology : KJO
Purpose This study aimed to evaluate the risk of acute myocardial infarction (AMI) associated with intravitreal ranibizumab in age-related macular degeneration (AMD). Methods This nationwide retrospective case-crossover study using data from the Korean National Health Insurance Service database included patients diagnosed with exudative AMD using t...
Kim, Se Young Yoon, Myung Hun Chin, Hee Seung
Published in
Korean Journal of Ophthalmology : KJO
Purpose To investigate the effect of intravitreal anti-vascular endothelial growth factor (VEGF) injections on ganglion cell-inner plexiform layer (GCIPL) thickness in patients with age-related macular degeneration (AMD). Methods This retrospective study included patients with continuous anti-VEGF treatment who were administered at least three cons...
