Mallet, Romain Modzelewski, Romain Lequesne, Justine Mihailescu, Sorina Decazes, Pierre Auvray, Hugues Benyoucef, Ahmed Di Fiore, Fréderic Vera, Pierre Dubray, Bernard
...
Published in
Radiation Oncology
BackgroundSarcopenia is defined by a loss of skeletal muscle mass with or without loss of fat mass. Sarcopenia has been associated to reduced tolerance to treatment and worse prognosis in cancer patients, including patients undergoing surgery for limited oesophageal cancer. Concomitant chemo-radiotherapy is the standard treatment for locally-advanc...
Gupta, Tejpal Sinha, Shwetabh Ghosh-Laskar, Sarbani Budrukkar, Ashwini Mummudi, Naveen Swain, Monali Phurailatpam, Reena Prabhash, Kumar Agarwal, Jai Prakash
Published in
Radiation Oncology
PurposeTo compare long-term disease-related outcomes and late radiation morbidity between intensity-modulated radiation therapy (IMRT) and three-dimensional conformal radiotherapy (3D-CRT) in head and neck squamous cell carcinoma (HNSCC) in the setting of a prospective randomized controlled trial.MethodsPreviously untreated patients with early to m...
do Nascimento Santos Lima, Emanuelle Ferreira, Isabela Borges Lajolo, Paula Philbert Paiva, Carlos Eduardo de Paiva Maia, Yara Cristina das Graças Pena, Geórgia
Published in
Health and Quality of Life Outcomes
BackgroundQuality of life (QoL) is influenced in head and neck cancer (HNC) patients by a set of factors related to diagnosis, treatment and tumor impacts. The aim of this study was to evaluate the Quality of Life (QoL) changes in Head and Neck cancer (HNC) patients during treatment (radiotherapy and/or chemoradiotherapy).MethodsQoL was evaluated p...
Yang, Yilan Luo, Jurui Chen, Xingxing Yang, Zhaozhi Mei, Xin Ma, Jinli Zhang, Zhen Guo, Xiaomao Yu, Xiaoli
Published in
Journal of Experimental & Clinical Cancer Research
Recently, the focus of enhancing tumor radiosensitivity has shifted from chemotherapeutics to targeted therapies. Cyclin-dependent kinase 4 and 6 (CDK4/6) inhibitors are a novel class of selective cell cycle therapeutics that target the cyclin D-CDK4/6 complex and induce G1 phase arrest. These agents have demonstrated favorable effects when used as...
Mehrzadi, Mohammad Hossein Hosseinzadeh, Azam Juybari, Kobra Bahrampour Mehrzadi, Saeed
Published in
Cancer Cell International
Urological cancers are responsible for thousands of cancer-related deaths around the world. Despite all developments in therapeutic approaches for cancer therapy, the absence of efficient treatments is a critical and vital problematic issue for physicians and researchers. Furthermore, routine medical therapies contribute to several undesirable adve...
Kim, Kyung Nam Hwangbo, Yonghun Jeon, Seok-gy Kim, Jaehoon Han, Soorim Kim, Kum Bae
Published in
Journal of the Korean Physical Society
A cancer treatment device using a very high energy electron beam has been studied as a new radiation therapy method because of its deep penetration depth, dose characteristics that are better than those of the existing X-ray method, and easy adjustment of the irradiation direction compared to existing equipment. For this treatment, compact high-ene...
Bi, Jianping Wei, Wei Hu, Desheng Han, Guang
Published in
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
Choi, Jinyeong Kim, Gaeun Cho, Su Bin Im, Hyung-Jun
Published in
Journal of Nanobiotechnology
Radiotherapy is an essential step during the treatment of glioblastoma multiforme (GBM), one of the most lethal malignancies. The survival in patients with GBM was improved by the current standard of care for GBM established in 2005 but has stagnated since then. Since GBM is a radioresistant malignancy and the most of GBM recurrences occur in the r...
Rijken, James Crowe, Scott Trapp, Jamie Kairn, Tanya
Radiation therapy of the spine, as recourse for spinal tumours, is an effective method of achieving pain reduction and local control. Hypofractionated techniques like stereotactic body radiation therapy and especially stereotactic radiosurgery are quickly becoming more popular as studies are published demonstrating their superior outcomes. This rev...
Lorat, Yvonne Fleckenstein, Jochen Görlinger, Patric Rübe, Christian Rübe, Claudia E
Published in
Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al]
53BP1 foci detection in peripheral blood lymphocytes (PBLs) by immunofluorescence microscopy (IFM) is a sensitive and quantifiable DNA double-strand break (DSB) marker. In addition, high-resolution transmission electron microscopy (TEM) with immunogold labeling of 53BP1 and DSB-bound phosphorylated Ku70 (pKu70) can be used to determine the progress...
