Teng, Alexandra E Noor, Benjamin Ajijola, Olujimi A Yang, Eric H
Published in
Current oncology reports
Cardiovascular autonomic dysfunction (AD) among cancer survivors is increasingly being recognized. However, the mechanisms and incidence are poorly understood. In this review, the clinical features, diagnostic modalities, proposed mechanisms, and currently available treatments of cardiovascular AD in cancer survivors are described. Much of our curr...
Dohm, Ammoren Diaz, Roberto Nanda, Ronica H.
Published in
Current Oncology Reports
Purpose of ReviewOlder patients represent a unique subgroup of the cancer patient population for which the role of radiation therapy (RT) requires special consideration. This review will discuss many of these considerations as well as various radiation treatment techniques in the context of a variety of disease sites.Recent FindingsSeveral recent s...
Hadoux, Julien Blanchard, Pierre Scoazec, Jean-Yves Burtin, Pascal Planchard, David Malka, David Berdelou, Amandine Boige, Valérie Duvillard, Pierre Leboulleux, Sophie
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Published in
Neuroendocrinology
Background: Cancer survivors have a 14% increased risk of developing a malignancy compared with the general population. Second radiation-induced malignancies with different histologies have been described in different organs. Based on individual observations, we hypothesized that neuroendocrine carcinoma (NEC) could arise in irradiated organs. Meth...
Kherallah, Riyad Y Harrison, Darren Preventza, Ourania Silva, Guilherme V Dougherty, Kathryn G Coulter, Stephanie A Simpson, Leo Strickman, Neil E Mortazavi, Ali Palaskas, Nicolas
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Published in
International journal of cardiology
Chest radiation therapy (CRT) for malignant thoracic neoplasms is associated with development of valvular heart disease years later. As previous radiation exposure can complicate surgical treatment, transcatheter aortic valve replacement (TAVR) has emerged as an alternative. However, outcomes data are lacking for TAVR patients with a history of CRT...
Georgescu, Mihai Teodor Georgescu, Dragos Eugen Georgescu, Teodor Florin Serbanescu, Luiza Georgia
Published in
Case Reports in Oncology
Adenocarcinoma and adenosquamous carcinoma (AS) are 2 rare histological types of cervix uteri cancer constituting almost 20% of all cervix cancers, leading to a lack in patient management guidelines. We report the case of a 32-year-old woman with an oligometastatic cervix AS for which a multimodal treatment approach was used. Despite the patient’s ...
Zhou, Wei Liu, Meiyue Li, Xia Zhang, Peng Li, Jiong Zhao, Yue Sun, Guogui Mao, Weimin
Published in
Cell & Bioscience
BackgroundIncreased reactive oxygen species (ROS) production by arsenic treatment in solid tumors showed to be effective to sensitize cancer cells to chemotherapies. Arsenic nano compounds are known to increase the ROS production in solid tumors.MethodsIn this study we developed arsenic–ferrosoferric oxide conjugated Nano Complex (As2S2–Fe3O4, AFCN...
Seo, Sung Wook Kim, Jisoo Son, Jihye Lim, Sungbin
Published in
BMC Medical Informatics and Decision Making
BackgroundThe impact of adjuvant chemotherapy or radiation therapy on the survival of patients with synovial sarcoma (SS), which is a rare soft-tissue sarcoma, remains controversial. Bayesian statistical approaches and propensity score matching can be employed to infer treatment effects using observational data. Thus, this study aimed to identify t...
Uzunparmak, Burak Gao, Meng Lindemann, Antje Erikson, Kelly Wang, Li Lin, Eric Frank, Steven J Gleber-Netto, Frederico O Zhao, Mei Skinner, Heath D
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Published in
JCI insight
Caspase-8 (CASP8) is one of the most frequently mutated genes in head and neck squamous carcinomas (HNSCCs), and CASP8 mutations are associated with poor survival. The distribution of these mutations in HNSCCs suggests that they are likely to be inactivating. Inhibition of CASP8 has been reported to sensitize cancer cells to necroptosis, a regulate...
Bravery, Benjamin D Shi, Kate Nicholls, Luke Chelvarajah, Revadhi Tieu, Minh Thi Turner, Sandra Windsor, Apsara
Published in
Journal of cancer education : the official journal of the American Association for Cancer Education
This study aimed to determine final year students' core oncology and radiation oncology knowledge and attitudes about the quality of teaching in medical programmes delivered in Australia and New Zealand. Does the modern medical programme provide core oncology skills in this leading global cause of mortality and morbidity? An online survey was distr...
Ratosa, Ivica Orazem, Miha Scoccimarro, Erika Steinacher, Mateja Dominici, Luca Aquilano, Michele Cerbai, Cecilia Desideri, Isacco Ribnikar, Domen Marinko, Tanja
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Published in
Clinical breast cancer
The cyclin-dependent kinase 4/6 inhibitors (CDK4/6i) represent the standard treatment for hormone receptor-positive, human epidermal growth factor receptor 2-negative metastatic breast cancer. Data about the balance between efficacy and toxicity of combined palliative radiotherapy (RT) and CDK4/6 inhibition are lacking. We undertook a review of 46 ...