Liu, Zixuan Xia, Xiaomin Lv, Xuying Song, Erqun Song, Yang
Published in
Environmental pollution (Barking, Essex : 1987)
Iron-bearing nanoparticles (IBNPs) were abundant in particulate matter (PM). Due to their high reactivity, IBNPs were considered hazardous to human health, however, their toxic mode-of-action(s) are highly unclear. Ferroptosis is a novel programmed cell death (PCD) that highly associated with intracellular iron. However, the pro-ferroptotic effect ...
Kononenko, Veno Drobne, Damjana
The use of titanium suboxides, known as Magnéli phase TiO$_x$, is expected to increase in the near future due to their desirable properties. In order to use Magnéli phase TiO$_x$ nanoparticles safely, it is necessary to know how nanoparticles interact with biological systems. In this study, the cytotoxicity of three different Magnéli TiO$_x$ nanopa...
Yu, Xiao-Zhang Chu, Yun-Peng Zhang, Hua Lin, Yu-Juan Tian, Peng
Published in
Ecotoxicology (London, England)
It is evident that the plasma membrane NADPH oxidases (NOXs) play an important role in the generation of superoxide radicals (O2-•) in plants during defense responses. This study was to clarify activation of NOXs in oxidative damage in Oryza sativa during SCN- exposure, particularly in the roles of jasmonic acid (JA) and hydrogen sulfide (H2S) on t...
PLEŠKO, ERIK
V magistrskem delu je predstavljen razvoj robotskega mehanizma za pobiranje stebelne zelenjave. Najprej so predstavljene uveljavljene rešitve, obravnavani različni pristopi in utemeljena izbira mehanizma. Sledi opis teoretične analize ter zasnove in izdelave mehanizma. Opisani sta zasnova in izdelava orodja za pobiranje rastlin. Predstavljena je st...
He, Jianbo Chen, Kai Deng, Tiancheng Xie, Jiewei Zhong, Kunjing Yuan, Jinbo Wang, Ziyi Xiao, Zhifeng Gu, Ronghe Chen, Delong
...
Published in
Frontiers in Pharmacology
The extravagant osteoclast formation and resorption is the main cause of osteoporosis. Inhibiting the hyperactive osteoclastic resorption is considered as an efficient treatment for osteoporosis. Rhaponticin (RH) is a small molecule that has been reported to possess anti-inflammatory, anti-allergic, anti-fibrotic, and anti-diabetic activities. Howe...
lin, mei-yi cheng, wan-ting cheng, hui-ching chou, wan-ching chen, hsiu-i hsiu-chung, ou tsai, kun-ling
Doxorubicin (Dox) is an effective anthracycline anticancer drug. However, recent studies have revealed that Dox resistance is a highly critical issue, and a significant reason for treatment failure. Baicalin is a flavonoid component in the roots of Scutellaria baicalensis Georgi / however, whether baicalin can increase chemosensitivity in breast ca...
antognelli, cinzia marinucci, lorella frosini, roberta macchioni, lara talesa, vincenzo nicola
Bone metastases from prostate cancer (PCa) result from a complex cross-talk between PCa cells and osteoblasts (OB). Thus, targeting this interplay has become an attractive strategy to interfere with PCa bone dissemination. The agents currently used in clinical trials have proved ineffective, boosting research to identify additional mechanisms that ...
dyshlovoy, sergey a. pelageev, dmitry n. jakob, lea s. borisova, ksenia l. hauschild, jessica busenbender, tobias kaune, moritz khmelevskaya, ekaterina a. graefen, markus bokemeyer, carsten
...
Development of resistance to currently available standard therapies in advanced prostate cancer (PCa) emphasizes the need for novel therapeutic options. Here, we report the synthesis of new hybrid molecules consisting of 2-chloroethylthio and 1,4-naphthoquinone pharmacophores and describe their activity in PCa. In screening analyses, the introducti...
Savio, Luiz Eduardo Baggio Leite-Aguiar, Raíssa Alves, Vinícius Santos Coutinho-Silva, Robson Wyse, Angela T.S.
Published in
Redox Biology
• Purine metabolism contribute to oxidative stress via xanthine oxidase activity. • P2X7 receptor activation induces NADPH oxidase activation and superoxide production. • P2Y1 triggers the expression of antioxidant enzymes reducing oxidative stress. • Free radicals reduce CD39 and CD73 functionality.
Wang, Jing Luo, Yuan Gu, Yilin Wei, Hai-Lei
Published in
Frontiers in Microbiology
Pseudomonas fluorescens 2P24 is a plant growth-promoting rhizobacterium (PGPR) isolated from wheat take-all decline soil. Genomic analysis of strain 2P24 revealed the presence of a complete SPI-1 type III secretion system (T3SS) gene cluster on the chromosome with an organization and orientation similar to the SPI-1 T3SS gene clusters of Salmonella...
