Cao, Zhicheng Wang, Hongmei Chen, Jialin Zhang, Yanan Mo, Qingyun Zhang, Po Wang, Mingyue Liu, Haoyang Bao, Xueyang Sun, Yuzhi
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Published in
Bioactive materials
Osteochondral defects (OCD) cannot be efficiently repaired due to the unique physical architecture and the pathological microenvironment including enhanced oxidative stress and inflammation. Conventional strategies, such as the control of implant microstructure or the introduction of growth factors, have limited functions failing to manage these co...
Kim, Da Hye Lee, Hyesook Hwangbo, Hyun Kim, So Young Ji, Seon Yeong Kim, Min Yeong Park, Seh-Kwang Park, Sung-Ho Kim, Mi-Young Kim, Gi-Young
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Published in
Cutaneous and ocular toxicology
Numerous studies have linked particulate matter2.5 (PM2.5) to ocular surface diseases, but few studies have been conducted on the biological effect of PM2.5 on the cornea. The objective of this study was to evaluate the harmful effect of PM2.5 on primary rat corneal epithelial cells (RCECs) in vitro and identify the toxic mechanism involved. Primar...
Ovayolu, Ali Bostancieri, Nuray Turksoy, Vugar Ali Dogan, Ilkay Bulgan, Gonca Goksu Turkcuoglu, Ilgin
Published in
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
Preeclampsia (PrE) is a pregnancy-related disorder. PrE affects the health of the mother and/or the fetus binomial with short and/or long-term consequences. The role of oxidant/antioxidant molecules and aberrant maternal inflammation in PrE has been documented. However, the importance of antioxidant molecules such as thiols has been poorly document...
Toropitsyn, Evgeniy Pravda, Martin Rebenda, David Ščigalková, Ivana Vrbka, Martin Velebný, Vladimír
Published in
Journal of biomedical materials research. Part B, Applied biomaterials
Osteoarthritis (OA) is one of the most common musculoskeletal disorders in the world. OA is often associated with the loss of viscoelastic and tribological properties of synovial fluid (SF) due to degradation of hyaluronic acid (HA) by reactive oxygen species (ROS) and hyaluronidases. Viscosupplementation is one of the ways how to effectively resto...
Kim, So-Hee Lee, Seung-Eun Yoon, Jae-Wook Park, Hyo-Jin Oh, Seung-Hwan Lee, Do-Geon Pyeon, Da-Bin Kim, Eun-Young Park, Se-Pill
Published in
Animal bioscience
The present study investigated whether protodioscin (PD), a steroidal saponin mainly found in rhizome of Dioscorea species, alleviates oxidative stress-induced damage of porcine oocytes during in vitro maturation. Oocytes were treated with different concentrations of PD (0, 1, 10, 100, and 200 μM) in the presence of 200 μM H2O2 during in vitro matu...
Berner, Julia Bekeschus, Sander
Published in
Japanese Journal of Applied Physics
Cold physical plasma is a partially ionized gas that generates various components identified as potential anticancer compounds. Due to its topical application, cold plasmas are suitable, especially in dermatological applications. We, therefore, tested the cold plasma effects in skin cancer cells in vitro. An atmospheric pressure argon plasma jet wa...
Ge, Weipeng Guo, Xiaoxiao Song, Xiaomin Pang, Junling Zou, Xuan Liu, Yonglin Niu, Yongliang Li, Zhengqing Zhao, Hongmei Gao, Ran
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Published in
Cardiovascular research
Hypertension is the major cause of cardiovascular diseases and global mortality. Immunoglobulin E (IgE), which plays crucial roles in allergic diseases, has been implicated in the pathogenesis of vascular and cardiac remodelling via its receptor (FcεR1). In this study, we aimed to reveal the role of IgE and FcεR1 in hypertension. Herein, we reporte...
Wang, Jianquan Hao, Lingyun Li, Xinhua Liu, Sen
Published in
Frontiers in Bioengineering and Biotechnology
Insufficient oxygen supply at the tumor site and hypoxia caused during tumor treatment lead to a poor therapeutic effect and poor prognosis. Therefore, effectively overcoming the problem of hypoxia in tumors and avoiding hypoxia that compromises the efficacy of the treatment could improve the anti-tumor therapeutic effect. Thus, this study reports ...
Kuroyanagi, Yunato Tsuchiya, Jiro Jiang, Chunqi Mino, Sayaka Kasai, Hisae Motooka, Daisuke Iida, Tetsuya Satomi, Masataka Sawabe, Tomoo
Published in
Frontiers in Marine Science
Light is one of the most critical stimuli in the majority of living organisms. In the last two decades, blue light (BL) has become a major subject of attention because of developments in light-emitting diodes (LED). The effects of BL on eukaryotic organisms and phototrophic prokaryotes have been well studied, but the knowledge of its effects on non...
Lin, Yijun Wang, Yan Li, Pei-feng
Published in
Frontiers in Physiology
The nature of redox is electron transfer; in this way, energy metabolism brings redox stress. Lactate production is associated with NAD regeneration, which is now recognized to play a role in maintaining redox homeostasis. The cellular lactate/pyruvate ratio could be described as a proxy for the cytosolic NADH/NAD ratio, meaning lactate metabolism ...
