Early embryogenesis is characterized by the segregation of cell lineages that fulfill critical roles in the establishment of pregnancy and development of the fetus. The formation of the blastocyst marks the emergence of extraembryonic precursors, needed for implantation, and of pluripotent cells, which differentiate toward the major lineages of the...
Published in BMC Plant Biology
BackgroundGibberellins (GA3) are the most sprayed growth regulator for table grape production worldwide, increasing berry size of seedless varieties through pericarp cell expansion. However, these treatments also exacerbate berry drop, which has a detrimental effect on the postharvest quality of commercialized clusters. Several studies have suggest...
Interleukin-27 (IL-27) has shown promise in halting tumor growth and mediating tumor regression in several models, including prostate cancer. We describe our findings on the effects of IL-27 on the gene expression changes of TC2R prostate adenocarcinoma cells. We utilized RNAseq to assess profile differences between empty vector control, vector del...
Paratuberculosis or Johne&rsquo / s disease in cattle is a chronic granulomatous gastroenteritis caused by infection with Mycobacterium avium subspecies paratuberculosis (MAP). Paratuberculosis is not treatable / therefore, the early identification and isolation of infected animals is a key point to reduce its incidence. In this paper, we analyse R...
Published in BMC Bioinformatics
BackgroundRNA sequencing has become an increasingly affordable way to profile gene expression patterns. Here we introduce a workflow implementing several open-source softwares that can be run on a high performance computing environment.ResultsDeveloped as a tool by the Bioinformatics Shared Resource Group (BISR) at the Ohio State University, we hav...
Published in BMC Research Notes
ObjectivesWe report a transcriptome acquisition for the bath sponge Spongia officinalis, a non-model marine organism that hosts rich symbiotic microbial communities. To this end, a pipeline was developed to efficiently separate between bacterial expressed genes from those of eukaryotic origin. The transcriptome was produced to support the assessmen...
bitstream/item/206383/1/417-2764-1-PB.pdf
Published in International journal for parasitology. Drugs and drug resistance
In Brazil, cutaneous leishmaniasis is caused predominantly by L. (V.) braziliensis. The few therapeutic drugs available exhibit several limitations, mainly related to drug toxicity and reduced efficacy in some regions. Miltefosine (MF), the only oral drug available for leishmaniasis treatment, is not widely available and has not yet been approved f...
JOINTLESS (J) is a MADS-box gene that regulates inflorescence traits in tomato: its mutation reduces the number of flowers in the inflorescence, which reverts to leaf initiation, and suppresses the abscission zone (AZ) in the flower pedicels. It has been shown that the J protein physically interacts with other MADS-box transcription factors, MACROC...
Published in BMC Genomics
BackgroundMeloidogyne chitwoodi commonly known as Columbia root-knot nematode or CRKN is one of the most devastating pests of potato in the Pacific Northwest of the United States of America. In addition to the roots, it infects potato tubers causing internal as well as external defects, thereby reducing the market value of the crop. Commercial pota...
